Titan LRC-5K Plus Benchtop Low-Speed Refrigerated Centrifuge
| Brand | Titan |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Manufacturer |
| Product Category | Domestic |
| Model | LRC-5K Plus |
| Instrument Type | Benchtop Centrifuge |
| Speed Range | Up to 6000 rpm |
| Max RCF | 5150 × g |
| Max Capacity | 15 × 32 mL (horizontal rotor configuration) |
| Cooling Capability | Refrigerated (−20 °C to +40 °C) |
| Dimensions | 560 × 680 × 376 mm (W × D × H) |
Overview
The Titan LRC-5K Plus is a benchtop low-speed refrigerated centrifuge engineered for routine separation tasks in clinical laboratories, biotechnology facilities, and academic research settings. It operates on the principle of sedimentation under controlled gravitational force (RCF), where differential density and particle size enable phase separation of biological suspensions—including whole blood, cell cultures, tissue homogenates, and polymer solutions. Unlike high-speed or ultracentrifuges, the LRC-5K Plus is optimized for gentle yet effective pelleting of intact cells, organelles, and large macromolecular complexes at speeds up to 6000 rpm and RCF values reaching 5150 × g. Its integrated refrigeration system maintains precise temperature control between −20 °C and +40 °C during operation, minimizing thermal denaturation of heat-sensitive samples such as plasma, serum, lymphocytes, and enzyme preparations. The unit’s compact footprint (560 × 680 × 376 mm) allows seamless integration into standard laboratory cabinetry without compromising accessibility or serviceability.
Key Features
- Refrigerated operation with independent compressor-based cooling system ensuring stable thermal environment across all speed ranges
- Microprocessor-controlled brushless DC motor delivering high torque, low vibration, and extended service life
- Intuitive LCD interface with real-time display of speed (rpm), RCF, time, temperature, and rotor identification
- Automatic rotor recognition and speed limitation based on installed rotor geometry and tube configuration
- Soft acceleration/deceleration profiles to prevent sample resuspension and tube breakage
- Five-stage imbalance detection with automatic shutdown and audible/visual alerts
- Stainless steel chamber and rotor housing for corrosion resistance and ease of decontamination
- Compliance with IEC 61010-1 safety standards for laboratory electrical equipment
Sample Compatibility & Compliance
The LRC-5K Plus supports horizontal rotor configurations accommodating up to fifteen 32 mL conical tubes—ideal for blood bank processing, urine sediment analysis, and large-volume buffer exchanges. Compatible tube formats include polypropylene, polycarbonate, and glass vessels rated for centrifugal loads up to 5150 × g. All rotors are dynamically balanced and certified per ISO 15195 for calibration traceability. The system meets essential regulatory expectations for GLP-compliant environments, including audit-ready operational logs (via optional USB data export), temperature stability verification per ISO 13485 Annex A, and mechanical safety certification aligned with EN 61010-2-020. While not FDA 21 CFR Part 11–validated out-of-the-box, its firmware architecture supports secure user authentication and electronic record retention when integrated with validated LIMS platforms.
Software & Data Management
The LRC-5K Plus includes embedded firmware supporting programmable method storage (up to 99 protocols), cycle counter logging, and runtime diagnostics. Optional USB interface enables transfer of run history—including start/stop timestamps, actual vs. setpoint deviations, and error codes—to external PCs for quality documentation. No proprietary software installation is required; exported CSV files are compatible with Excel, LabArchives, and most ELN systems. Firmware updates are delivered via encrypted USB key to maintain integrity and version control. Audit trail functionality records operator ID (when paired with external RFID badge reader), parameter changes, and emergency stop events—facilitating internal QA reviews and external inspections.
Applications
- Clinical diagnostics: Separation of serum/plasma from whole blood, urinalysis sediment preparation, CSF clarification
- Cell biology: Harvesting adherent and suspension mammalian cells, isolation of peripheral blood mononuclear cells (PBMCs)
- Industrial microbiology: Clarification of fermentation broths, yeast/bacterial pellet recovery
- Food & beverage QA: Fat separation in milk homogenates, particulate removal in juice concentrates
- Environmental testing: Sedimentation of suspended solids in wastewater samples prior to TOC or metal analysis
FAQ
What is the minimum operating temperature, and how quickly does the chamber reach setpoint?
The refrigeration system achieves −20 °C nominal chamber temperature; pre-cool time to −10 °C at ambient 25 °C is approximately 18 minutes.
Is rotor calibration required before first use?
No—each rotor is factory-balanced and serialized. However, users must verify rotor identification via the LCD menu upon installation.
Can the LRC-5K Plus be used for density gradient centrifugation?
Yes, when equipped with compatible swing-out rotors and appropriate tube carriers, it supports sucrose, Ficoll, and Percoll gradients for subcellular fractionation.
Does the unit support continuous operation mode?
No—it is designed for batch-mode operation with programmable run durations up to 99 hours, 59 minutes, and 59 seconds.
Are replacement rotors and adapters available through authorized distributors?
Yes—Titan provides full rotor lifecycle support, including spare parts, recalibration services, and compatibility documentation for ISO-certified replacements.
