Labotery ZQPW-70/300 Horizontal Orbital Incubator Shaker

Overview

The Labotery ZQPW-70/300 is a high-performance horizontal orbital incubator shaker engineered for precise temperature-controlled agitation of biological and microbiological samples in research, quality control, and bioprocess development laboratories. Designed around a robust dual-function architecture—integrating refrigerated temperature control (4–65°C) with programmable orbital shaking—it supports aerobic culture growth, enzyme kinetics, solubility studies, and suspension-based cell expansion under tightly regulated thermal and mechanical conditions. Its core operational principle combines Peltier-assisted or compressor-based active cooling with PID-driven microprocessor temperature regulation and brushless DC motor–driven eccentric cam oscillation, delivering stable thermal homogeneity (±0.8°C at 37°C) and mechanical reproducibility (±1 rpm frequency accuracy). Unlike vertical shakers, the horizontal configuration minimizes shear stress on sensitive cell cultures while maximizing usable shelf area and volumetric loading capacity—up to 5000 mL × 8 flasks or equivalent multi-vessel arrangements.

Key Features

• Refrigerated operation down to 4°C enabled by an imported CFC-free hermetic compressor, paired with a dedicated dust filtration system for extended service life and reduced maintenance intervals.
• Orbital motion driven by a maintenance-free, high-efficiency brushless DC motor with integrated encoder feedback—ensuring precise speed control, programmable forward/reverse/stop sequencing, and >20,000-hour operational lifespan.
• Large-capacity stainless steel chamber (940 × 570 × 680 mm) with electropolished mirror-finish interior, seamless welds, and autoclavable corner radii for ISO Class 5–7 cleanroom-compatible cleaning protocols.
• Double-layer tempered glass observation door with argon-filled interlayer for thermal insulation and real-time visual monitoring without compromising temperature stability.
• Multi-mode programmability: users may define up to 16-step time-temperature-shake profiles—including alternating direction cycles, dwell periods, and ramp rates—with non-volatile memory retention during power interruption.
• Comprehensive safety architecture including door interlock (instantaneous motor stop), over-temperature cutoff (hardware + software redundant logic), and self-diagnostic firmware that reports fault codes for temperature sensor drift, motor stall, or compressor overload.

Sample Compatibility & Compliance

The ZQPW-70/300 accommodates standard laboratory vessels—including Erlenmeyer flasks (100–5000 mL), test tubes, deep-well plates, and custom bioreactor bags—via adjustable universal spring clamps or optional platform adapters. Its chamber design includes a Ø30 mm pass-through port for external probe insertion (e.g., dissolved oxygen, pH, or CO₂ sensors), supporting closed-loop process monitoring per ASTM D5540 or USP environmental control guidelines. The unit complies with IEC 61010-1:2010 for laboratory electrical safety and meets EMC requirements per EN 61326-1:2013. While not certified for GMP manufacturing environments out-of-the-box, its audit-ready features—including password-protected parameter locking, electronic log export (CSV), and timestamped event history—support alignment with FDA 21 CFR Part 11 when deployed with validated SOPs and periodic IQ/OQ/PQ documentation.

Software & Data Management

The embedded PID controller provides local setpoint management via a 5.7-inch backlit LCD interface with tactile navigation keys. For advanced integration, the optional true-color touchscreen controller adds Ethernet/RS485 connectivity, enabling remote monitoring through Labotery’s L-Link™ software suite (Windows/Linux compatible). This platform supports real-time graphing of temperature and RPM traces, automated report generation (PDF/Excel), and secure user role assignment (admin/operator/auditor). All logged data—including timestamps, setpoints, deviations, and alarm events—are stored with SHA-256 hash integrity verification, fulfilling ALCOA+ principles for data reliability in GLP-compliant workflows.

Applications

• Microbial culture expansion for antibiotic susceptibility testing (CLSI M07-A10) and bioburden analysis.
• Recombinant protein expression in E. coli or yeast using controlled aeration and temperature ramping protocols.
• Suspension-based mammalian cell line adaptation prior to bioreactor scale-up.
• Enzymatic reaction optimization under varied thermal and mixing conditions (e.g., lipase activity assays).
• Environmental simulation studies requiring long-term stability at sub-ambient temperatures (e.g., cold-adapted psychrophile cultivation).
• Quality assurance of liquid media sterility and homogeneity prior to dispensing.

FAQ

Does the ZQPW-70/300 support GLP-compliant data integrity requirements?
Yes—when equipped with the optional touchscreen controller and operated under defined access controls, it records tamper-evident audit trails meeting ALCOA+ criteria and aligns with Annex 11 and 21 CFR Part 11 expectations for electronic records.
Can the unit maintain 4°C continuously during summer ambient conditions above 35°C?
Yes—the compressor cooling system is rated for continuous operation at full load under 40°C/80% RH ambient conditions, verified per ISO 16770:2021 environmental testing standards.
Is the oscillation amplitude adjustable?
No—the Ø26 mm fixed orbit is optimized for culture aeration efficiency and mechanical stability across the full 30–300 rpm range; variable amplitude would compromise thermal uniformity and motor longevity.
What validation documentation is provided with shipment?
Each unit ships with a Factory Acceptance Test (FAT) report, calibration certificate traceable to NIST standards for temperature and speed sensors, and a complete set of mechanical drawings and electrical schematics for IQ/OQ protocol development.
Are third-party vessel holders (e.g., Infors HT MultiTrak) compatible?
Mechanical compatibility is confirmed for ISO-standard 940 × 570 mm platforms; however, electrical or communication integration with proprietary controllers requires Labotery’s OEM interface module (part #LZ-QI-MT).