Suying SY-150L Temperature and Humidity Controlled Environmental Test Chamber

Overview

The Suying SY-150L Temperature and Humidity Controlled Environmental Test Chamber is an engineered platform for precise, long-term simulation of controlled climatic conditions in compliance with international stability testing protocols. Designed around a dual-loop PID-controlled refrigeration-heating system and a steam-based humidification mechanism with independent dehumidification, the chamber maintains stable thermal and hygric environments through continuous real-time feedback from high-accuracy Pt100 sensors and capacitive RH transducers. Its 150-liter internal volume (500 × 600 × 500 mm W×D×H) supports standardized ICH Q1A(R2), WHO TRS 953 Annex 2, and USP stability study configurations—including long-term storage at 25 °C/60 %RH and accelerated testing at 40 °C/75 %RH over six-month durations. The unit’s stainless-steel interior, insulated double-wall construction (100 mm polyurethane foam), and leak-tight door seal ensure minimal thermal bridging and consistent chamber-wide uniformity.

Key Features

• Robust chamber architecture with 304 stainless-steel interior and electrostatically coated steel exterior for corrosion resistance and cleanroom compatibility
• Dual-stage cooling system using environmentally compliant R134a refrigerant, coupled with adjustable electric heating elements for rapid temperature ramping and recovery
• Steam-generator-based humidification with condensate drainage management and anti-dry-burn protection to prevent sensor drift and chamber contamination
• Independent solid-state dehumidification module—operational without compressor cycling—to maintain low-RH setpoints with high repeatability
• Integrated data logging capability (optional Ethernet or USB interface) supporting time-stamped temperature and humidity records at user-defined intervals (1–60 min)
• Compliance-ready design: meets mechanical and electrical safety requirements per IEC 61010-1; includes hardware-level password protection and audit trail enablement for GLP/GMP-aligned operation

Sample Compatibility & Compliance

The SY-150L accommodates standard stability test packages including ICH-compliant trays (e.g., 300 × 400 mm aluminum racks), pharmaceutical blister packs, vials on shelving, and electronic PCB assemblies mounted on non-outgassing fixtures. Internal airflow is optimized via rear-mounted centrifugal fans with laminar flow diffusers to minimize localized gradients—validated per ISO 16750-4 (automotive), ASTM D4332 (conditioning of plastics), and ISO 14644-1 Class 8 cleanroom-compatible operation. All control firmware and calibration documentation support traceability to NIST-traceable standards. Optional IQ/OQ documentation packages are available to facilitate FDA 21 CFR Part 11–compliant validation in regulated pharmaceutical and medical device environments.

Software & Data Management

The embedded controller features a 7-inch color TFT touchscreen with intuitive menu navigation and multilingual UI (English, German, Spanish). Real-time trend graphs display concurrent temperature/humidity profiles, alarm history, and deviation alerts. Logged data exports in CSV format are compatible with LIMS integration and statistical process control (SPC) tools such as JMP or Minitab. For networked labs, optional Ethernet connectivity enables remote monitoring via Modbus TCP or HTTP API endpoints—supporting centralized fleet management and automated report generation. All system events—including door openings, power interruptions, and parameter changes—are recorded with timestamps and operator IDs, fulfilling ALCOA+ data integrity principles.

Applications

• Pharmaceutical stability studies: long-term, intermediate, and accelerated testing per ICH Q1 guidelines
• Biological sample conditioning prior to assay—e.g., cell culture media equilibration, enzyme reconstitution
• Electronics reliability testing: moisture sensitivity level (MSL) evaluation per JEDEC J-STD-020
• Food packaging shelf-life modeling under variable RH conditions to assess barrier performance
• Material aging tests for polymers, adhesives, and composites under combined thermal-hygrometric stress
• Calibration reference environments for hygrometers, thermistors, and environmental sensors

FAQ

What regulatory standards does the SY-150L comply with for pharmaceutical stability testing?
It supports execution of ICH Q1A(R2), WHO TRS 953 Annex 2, and USP protocols; full qualification documentation (IQ/OQ) is available upon request.
Can the chamber operate continuously at 10 °C and 98 %RH?
Yes—the refrigeration and humidification subsystems are independently controllable, enabling simultaneous low-temperature/high-humidity operation without condensation risk due to active dew-point management.
Is calibration certificate included with shipment?
A factory calibration report (traceable to national metrology institutes) is provided; on-site UKAS/NIST-accredited calibration services are available as an add-on.
What is the maximum allowable load mass without compromising uniformity?
For optimal performance, total payload should not exceed 30 kg; exceeding this may require extended stabilization time and impact uniformity margins per ISO 16750-4 Annex B.
Does the system support 21 CFR Part 11 compliance?
With optional software upgrade and user access control configuration, full electronic signature, audit trail, and role-based permissions can be enabled to meet Part 11 requirements.