Sanotac S0160 High-Pressure Precision Metering Pump (10 mL/min, 60 MPa)

Overview

The Sanotac S0160 High-Pressure Precision Metering Pump is an isocratic liquid delivery system engineered for demanding analytical and process-critical applications requiring stable, pulse-free flow under extreme pressure conditions. Operating on a dual-piston series architecture with floating piston design, the pump delivers precise volumetric displacement across its full range of 0.001–10 mL/min while maintaining continuous operation up to 60 MPa (8,700 psi). Its fundamental principle relies on positive displacement via synchronized reciprocating sapphire-rubbed pistons, minimizing compressibility effects and ensuring high reproducibility in low-compressibility solvents (e.g., water, methanol, acetonitrile) and moderately compressible media (e.g., CO₂-expanded liquids). Designed for integration into HPLC, SFC, catalytic evaluation reactors, microfluidic synthesis platforms, and supercritical fluid processing systems, the S0160 meets functional requirements aligned with ISO 9001-manufactured instrumentation and supports traceable calibration protocols compliant with GLP and GMP laboratory practices.

Key Features

• Dual-piston series configuration with floating piston mechanism ensures mechanical stability and reduces wear-induced drift over extended duty cycles.
• Flow accuracy of ±0.1% and repeatability ≤0.1% RSD—validated per ASTM D3487 and ISO 5725-2 guidelines using gravimetric verification at multiple setpoints (0.1, 1.0, 5.0, and 10.0 mL/min).
• Active pressure pulsation suppression (<0.1 MPa) achieved through cam-profile compensation and real-time electronic flow modulation, critical for UV/VIS detector stability in chromatographic applications.
• Integrated plunger back-flush function minimizes particulate accumulation and seal degradation, extending maintenance intervals beyond 6,000 operating hours under typical aqueous/organic solvent conditions.
• Multi-protocol communication stack (Modbus RTU/ASCII, Sanotac proprietary protocol) enables deterministic control within PLC-based DCS environments and SCADA-level supervisory architectures.
• Configurable analog input (0–5 V / 4–20 mA) and digital I/O support closed-loop mass-flow control when interfaced with inline load cells or Coriolis meters in reactor feed systems.

Sample Compatibility & Compliance

The S0160 accommodates a broad chemical compatibility envelope due to its wetted-path construction: 316L stainless steel housing, sapphire check valves, PTFE seals, and ceramic piston coatings resist corrosion from strong acids (e.g., 6 M HCl), bases (e.g., 2 M NaOH), and halogenated solvents (e.g., chloroform, dichloromethane). It is rated for use with supercritical CO₂ (up to 60 °C, 30 MPa) and subcritical water (≤350 °C, ≤25 MPa) when paired with optional high-temperature column heaters and thermal shielding. The pump complies with CE electromagnetic compatibility directives (2014/30/EU), RoHS 2011/65/EU, and carries factory-certified conformity to IEC 61000-6-2/6-4 immunity and emission standards. While not FDA 21 CFR Part 11–certified out-of-the-box, audit-ready data logging (with timestamped event records, parameter change logs, and method execution history) can be enabled via optional firmware upgrade for regulated QC/QA laboratories.

Software & Data Management

The embedded firmware supports local parameter configuration via intuitive menu navigation on the 256×64 monochrome LCD. Optional PC-based software provides full remote orchestration—including gradient programming (linear, step, custom profile), real-time pressure/flow curve plotting, and CSV export of time-stamped operational datasets (flow rate, pressure, temperature, error codes). All methods are stored in non-volatile memory with version tagging and user-access controls (admin/operator levels). Calibration coefficients are stored separately per flow channel and may be updated without firmware reflash. Audit trails record operator ID, timestamp, and action type for every parameter modification—supporting ALCOA+ data integrity principles. Integration with LabArchives ELN or Thermo Fisher SampleManager LIMS is achievable via RESTful API wrapper (available upon request).

Applications

• HPLC and preparative LC systems requiring stable isocratic elution at pressures >40 MPa (e.g., sub-2 µm particle columns, core-shell media).
• Catalytic screening rigs where stoichiometric reagent dosing must be maintained across variable backpressure profiles (e.g., fixed-bed reactors, trickle-bed systems).
• Supercritical fluid chromatography (SFC) and extraction platforms utilizing CO₂/methanol mobile phases at 10–30 MPa.
• Microreactor and flow chemistry setups demanding <1% CV flow precision at microliter-per-minute rates for kinetic studies or residence time distribution analysis.
• Electrochemical synthesis cells requiring inert, pulse-free electrolyte delivery under elevated pressure to suppress gas bubble formation.
• High-pressure rheometry sample loading where volumetric consistency directly impacts shear-rate fidelity.

FAQ

What is the minimum programmable flow increment?
The S0160 supports 0.001 mL/min resolution across its entire 0.001–10.000 mL/min range.
Can the pump operate continuously at 60 MPa?
Yes—rated for continuous operation at 60 MPa with appropriate solvent compatibility and thermal management; derating is recommended above 55 °C ambient.
Is the flow path compatible with hydrofluoric acid (HF)?
No—HF attacks both 316L stainless steel and sapphire components; alternative materials (e.g., Hastelloy C-276, fused silica) require custom engineering and are not covered under standard warranty.
Does the pump include built-in leak detection?
Not as a hardware feature; however, pressure deviation alarms (configurable threshold ±0.5 MPa) and flow error detection (±2% deviation for >5 s) trigger relay outputs for external interlock integration.
How is calibration traceability established?
Factory calibration uses NIST-traceable gravimetric standards; users may perform field recalibration using certified flow meters (e.g., Bronkhorst EL-FLOW Select) and store correction factors per flow segment.