Sanotac SPF0502 PTFE-Lined Constant Flow Pump
| Brand | Sanotac |
|---|---|
| Model | SPF0502 |
| Flow Range | 0.01–50.00 mL/min |
| Flow Increment | 0.01 mL/min |
| Flow Accuracy | ±0.5% |
| Flow Precision (RSD) | ≤0.1% |
| Maximum Pressure | 2 MPa |
| Pressure Pulsation | ≤0.2 MPa |
| Fluid Path Materials | PTFE, PCTFE, Sapphire, Ceramic |
| Tubing Connection | 1/16" Standard |
| Display | 256×64 Dot Matrix Backlit LCD |
| Control | Front Panel or Open-Protocol Computer Remote Control (RS232/USB) |
| Power Supply | 85–264 VAC, 50 Hz |
| Dimensions | 370 × 240 × 152 mm |
| Compliance | Designed for GLP/GMP-aligned lab environments |
Overview
The Sanotac SPF0502 PTFE-Lined Constant Flow Pump is an engineered solution for precise, chemically inert fluid delivery in demanding analytical and process-critical laboratory applications. Based on dual parallel plunger architecture with floating plunger design, it operates via positive displacement to deliver stable volumetric flow across a wide dynamic range—from trace-level additions (0.01 mL/min) to high-throughput delivery (50.00 mL/min). Its fluid path is constructed entirely from fluoropolymer materials (PTFE and PCTFE), sapphire check valves, and ceramic components, ensuring exceptional resistance to aggressive solvents, strong acids, alkalis, and oxidizing reagents. Unlike stainless-steel or titanium alternatives, the SPF0502 eliminates metal ion leaching and surface catalytic effects—making it indispensable for ultra-trace analysis, catalyst dosing, supercritical fluid systems, and corrosion-prone reaction workflows.
Key Features
- Dual Parallel Plunger System with Floating Design: Minimizes seal wear under sustained pressure (up to 2 MPa), extending service life of critical sealing elements and maintaining long-term flow stability.
- Microprocessor-Controlled Flow Compensation: Integrates solvent compressibility correction and multi-point flow calibration curves to ensure accuracy across viscosity and temperature gradients.
- Low-Pressure Pulsation Architecture: Combines optimized cam profile geometry with real-time electronic pulse suppression, achieving pressure ripple ≤0.2 MPa—critical for baseline stability in LC detection and sensitive reactor feed control.
- Open Communication Protocol: Supports RS232 and USB interfaces with documented ASCII command set, enabling seamless integration into third-party chromatography data systems (CDS), LIMS, or custom SCADA environments without proprietary software lock-in.
- Intuitive Human-Machine Interface: Features a 256×64 backlit monochrome LCD with 10 programmable user methods for flow rate, gradient shape (isocratic, linear, step), and start/stop timing—accessible via tactile keypad or remote command.
Sample Compatibility & Compliance
The SPF0502 is validated for continuous operation with halogenated solvents (e.g., chloroform, DCM), concentrated HNO₃/HF mixtures, peroxides, and supercritical CO₂. Its all-fluoropolymer wetted path meets USP Class VI biocompatibility requirements for non-leaching contact surfaces. While not certified to FDA 21 CFR Part 11 out-of-the-box, its audit-ready event logging (via optional firmware update) supports GLP-compliant record retention when deployed with timestamped method execution and error reporting. Manufacturing adheres to ISO 9001:2015 quality management standards at Sanotac’s Shanghai facility.
Software & Data Management
The pump operates natively via front-panel controls but is fully controllable through open ASCII protocol—enabling direct scripting in Python, LabVIEW, or MATLAB. Optional PC-based configuration utility provides graphical gradient editor, flow calibration wizard, and system diagnostics dashboard. All operational parameters—including flow rate, pressure reading, error codes, and method execution logs—are timestamped and exportable as CSV for traceability. When integrated into regulated environments, users may implement external audit trail mechanisms compliant with Annex 11 and ALCOA+ principles.
Applications
- HPLC/UHPLC auxiliary solvent delivery and mobile phase blending
- Catalyst injection in batch and continuous-flow reactors (e.g., Fischer-Tropsch, hydrogenation)
- Supercritical fluid chromatography (SFC) and extraction (SFE) co-solvent metering
- Electrolyte dosing in battery R&D (Li-ion, solid-state, flow batteries)
- Controlled reagent addition in microreactor and photochemical synthesis platforms
- Calibration standard delivery for flowmeter validation per ISO 4064
FAQ
Is the SPF0502 suitable for use with hydrofluoric acid (HF)?
Yes—the PTFE/PCTFE fluid path and sapphire valves provide full compatibility with concentrated HF solutions up to 48%, provided operating temperature remains below 80°C.
Can this pump be integrated into a GMP-regulated QC lab workflow?
It supports GMP alignment when paired with validated software layers that enforce user authentication, electronic signatures, and change-controlled method storage—though standalone hardware does not include 21 CFR Part 11 features.
What maintenance intervals are recommended for the plunger seals?
Under typical usage (≤1.5 MPa, ambient temperature, non-abrasive solvents), seal replacement is recommended every 6,000–8,000 hours of operation, with visual inspection advised every 1,000 hours.
Does the pump support gradient elution with multiple solvents?
The SPF0502 is a single-channel constant-flow unit; gradient formation requires external low-dead-volume mixing modules or integration with multi-pump systems via synchronized command protocols.
Is firmware upgrade capability available?
Yes—field-upgradable firmware is distributed via Sanotac’s technical support portal, including enhancements to communication robustness, extended error diagnostics, and enhanced logging granularity.
