Sanotac IAP-0010 Intelligent High-Pressure Constant Flow Pump
| Brand | Sanotac |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Direct Manufacturer |
| Model | IAP-0010 |
| Max. Flow Rate | 10 mL/min |
| Max. Operating Pressure | 42 MPa |
| Flow Accuracy | < ±0.5% |
| Communication Interfaces | RS-232, RS-485, RS-422, USB |
| Protocols | Modbus RTU, Modbus ASCII, Custom Serial Protocol |
| Analog Input Support | 0–5 V DC, 4–20 mA |
| Control Modes | Constant Flow, Gradient Flow |
| Data Export Format | Excel (.xlsx) |
| Compliance | Designed for GLP-compliant lab environments and compatible with FDA 21 CFR Part 11 audit trail requirements (when integrated with validated software) |
Overview
The Sanotac IAP-0010 Intelligent High-Pressure Constant Flow Pump is an engineered precision fluid delivery system designed for applications demanding stable, programmable, and traceable volumetric or mass-based flow control under elevated pressure conditions. Utilizing a dual-piston positive displacement architecture with active pressure compensation and real-time closed-loop feedback, the pump operates on the principle of reciprocating displacement with electronic motion synchronization—ensuring minimal pulsation (<2% peak-to-peak at rated flow) and high reproducibility across extended operational cycles. Its 42 MPa maximum pressure rating enables compatibility with high-backpressure analytical systems including preparative HPLC, supercritical fluid chromatography (SFC), catalytic reaction screening rigs, and high-pressure microreactors. Unlike basic peristaltic or syringe pumps, the IAP-0010 delivers true constant-flow performance independent of system resistance changes, making it suitable for dynamic process environments where inlet pressure fluctuates—such as in gravimetric feed control loops interfaced with balance-based mass-loss monitoring.
Key Features
- Real-time dual-curve visualization: Simultaneous graphical display of pressure (MPa) and flow rate (mL/min or g/min) on integrated touchscreen interface, updated at 10 Hz sampling frequency
- Configurable protection logic: Programmable upper/lower pressure limits with automatic shutdown and audible alarm; pre-run pressure zeroing function to eliminate baseline drift
- Dual-unit flow definition: Seamless switching between volumetric (mL/min) and gravimetric (g/min) output modes using user-defined fluid density inputs
- On-device flow calibration: Dedicated calibration wizard allowing multi-point linearization against reference flow meters or gravimetric standards
- Two operational profiles: Constant-flow mode for steady-state delivery; gradient-flow mode supporting up to 16 programmable time/flow segments with ramp, step, or hold functions
- Industrial-grade connectivity: Native support for RS-232, RS-485, RS-422, and USB 2.0 interfaces; configurable baud rates (1200–115200 bps); hardware flow control (RTS/CTS)
- Protocol flexibility: Built-in Modbus RTU and Modbus ASCII slave functionality; optional custom ASCII command set for OEM integration
- Analog I/O compatibility: 0–5 V DC and 4–20 mA input channels for external PLC coordination or analog setpoint modulation
- Data integrity assurance: Local storage of time-stamped pressure and flow curves with export to .xlsx format; timestamped configuration snapshots including port settings, protection thresholds, and program sequences
- Closed-loop mass-feed capability: Direct integration with laboratory balances via serial or analog interface for real-time feed rate adjustment based on mass-loss feedback
Sample Compatibility & Compliance
The IAP-0010 is chemically compatible with a broad range of solvents, acids, bases, and slurries when equipped with standard PTFE, sapphire, and 316L stainless steel wetted components. It meets ISO 8573-1:2010 Class 4 purity requirements for compressed air–driven auxiliary systems (if applicable) and conforms to IEC 61000-6-3:2019 for electromagnetic emissions. For regulated environments, the pump’s firmware supports audit-trail-enabling features—including user login tracking, parameter change logging, and electronic signature prompts—when deployed within a validated software ecosystem compliant with FDA 21 CFR Part 11 and EU Annex 11. All mechanical and electrical design follows IEC 61010-1:2010 safety standards for laboratory equipment.
Software & Data Management
The pump operates standalone via its embedded GUI or integrates into centralized control platforms using native Modbus registers (holding registers 40001–40100 for flow setpoint, pressure readback, status flags, and error codes). Sanotac’s SanoFlu PC software (Windows 10/11, x64) provides remote configuration, multi-pump synchronization, batch script execution, and automated report generation. All recorded datasets include ISO 8601 timestamps, operator ID metadata, and instrument serial number tagging—enabling full traceability per GLP and GMP documentation requirements. Raw curve data exports retain millisecond-level temporal resolution and are structured for direct import into MATLAB, Python (pandas), or LabVIEW for advanced statistical process analysis.
Applications
- Preparative liquid chromatography requiring stable eluent delivery at pressures up to 42 MPa
- In-line catalytic reaction studies with automated reagent dosing and pressure-resilient solvent delivery
- Supercritical CO₂ extraction systems needing precise co-solvent metering under variable backpressure
- High-pressure material synthesis reactors where stoichiometric feed accuracy directly impacts crystallinity and yield
- Automated quality control workflows integrating with balance-based loss-in-weight feeding for API manufacturing
- Method development labs validating flow stability across viscosity gradients (e.g., polymer solutions, nanoparticle dispersions)
FAQ
What is the minimum controllable flow rate of the IAP-0010?
The pump achieves stable delivery down to 0.001 mL/min with <±0.5% repeatability, verified using calibrated glass capillary flowmeters traceable to NIST standards.
Can the IAP-0010 be used in explosion-proof environments?
The base model is rated for general laboratory use (IEC 60529 IP20). For hazardous area deployment, consult Sanotac Engineering for ATEX/IECEx-certified variants with intrinsically safe barrier configurations.
Does the pump support automatic viscosity compensation?
No. Viscosity-dependent flow deviation is corrected manually via the built-in calibration routine using known reference fluids; real-time viscosity sensing requires external inline viscometer integration.
Is firmware update capability available over USB?
Yes—field-upgradable firmware is distributed as signed binary packages via Sanotac’s secure customer portal, with version rollback and checksum verification included.
How is compliance with 21 CFR Part 11 achieved?
The pump itself does not store electronic signatures. Full Part 11 compliance is realized only when paired with validated third-party SCADA or LIMS software that implements audit trails, role-based access, and digital signature workflows per §11.10 and §11.200.

