Sanotac TSP0510 Medium-Pressure Precision Reciprocating Pump

Overview

The Sanotac TSP0510 is a medium-pressure, dual-plunger reciprocating pump engineered for high-accuracy, low-pulsation fluid delivery in demanding laboratory and pilot-scale applications. It operates on the principle of positive displacement via synchronized cam-driven pistons, with real-time solvent compressibility compensation and dynamic flow calibration across its full operational range. Designed to meet the rigorous demands of preparative liquid chromatography, catalytic reaction feeding, supercritical fluid processing, and continuous-flow synthesis, the TSP0510 delivers stable volumetric flow rates from 10 mL/min up to 10,000 mL/min at a maximum rated pressure of 10 MPa (1450 psi). Its robust mechanical architecture—featuring a floating plunger mechanism, precision-ground cam profile, and imported Swiss single-use check valves—ensures long-term seal integrity and minimal maintenance under sustained high-pressure operation.

Key Features

• Microprocessor-controlled dual-piston synchronization with adaptive solvent compressibility correction for consistent volumetric accuracy across varying mobile phase compositions.
• Multi-point flow calibration algorithm enabling traceable, NIST-traceable flow accuracy (±0.5% RSD over 10–100% of full scale) without external flow meters.
• Programmable gradient generation combining isocratic, linear, and step profiles into custom composite curves—supporting method development for complex separations and multi-stage reaction control.
• Integrated electronic pulse damping and optimized cam geometry reducing pressure ripple to < ±0.2% of set pressure—critical for column stability in preparative HPLC and packed-bed reactors.
• Modular wetted-material options (316L stainless steel, titanium, PTFE, PCTFE, Hastelloy C-276, and PEEK) certified for compatibility with aggressive solvents, acids, bases, and supercritical CO₂.
• Open communication protocol (ASCII-based RS-485/RS-232) compliant with ASTM E1381 and ISO/IEC 11179 metadata standards—enabling seamless integration into third-party chromatography data systems and LIMS environments.

Sample Compatibility & Compliance

The TSP0510 supports a broad spectrum of process fluids—from aqueous buffers and organic solvents (acetonitrile, THF, DMF) to corrosive reagents (HF,浓H₂SO₄), molten salts, and supercritical carbon dioxide. All wetted-path configurations comply with ISO 8503-2 surface roughness requirements (<0.4 µm Ra) for critical pharmaceutical and catalyst-handling applications. The pump’s mechanical design conforms to CE Machinery Directive 2006/42/EC and carries IP54 ingress protection rating for laboratory ambient use. For regulated environments, audit trail logging (via optional external controller) supports GLP/GMP compliance per FDA 21 CFR Part 11 when paired with validated CDS software.

Software & Data Management

The embedded firmware includes a non-volatile memory bank supporting ten user-defined methods—each storing flow rate, pressure limit, gradient time program, and valve switching sequence. Real-time status telemetry (flow deviation, pressure deviation, motor temperature, valve actuation count) is accessible via serial interface and loggable to CSV or XML formats. Optional Ethernet gateway modules enable OPC UA server deployment for Industry 4.0 lab automation frameworks. All calibration coefficients and firmware revisions are digitally signed and version-locked to prevent unauthorized modification—meeting ALCOA+ data integrity principles.

Applications

• Preparative and semi-preparative liquid chromatography (LC) systems requiring stable flow at 5–10 MPa for fraction collection and purification.
• Catalyst dosing in continuous-flow hydrogenation, oxidation, and cross-coupling reactors—where stoichiometric precision directly impacts selectivity and yield.
• Supercritical fluid extraction (SFE) and impregnation setups using CO₂ or ethane as working media.
• Foam extrusion and polymer processing lines requiring metered co-injection of blowing agents and stabilizers.
• Electrolyte delivery in flow battery R&D and electrochemical cell testing rigs.
• Feedstock metering in fixed-bed and slurry-phase catalytic cracking (FCC) and hydrodesulfurization (HDS) bench-scale reactors.

FAQ

What is the minimum programmable flow rate with acceptable accuracy?
The TSP0510 maintains ≤1.0% RSD at 10 mL/min when operated with 50 mL pump heads and calibrated for the specific solvent viscosity and compressibility.
Can the pump be used with aggressive halogenated solvents such as anhydrous HF or ClF₃?
Yes—when configured with Hastelloy C-276 or PCTFE wetted components and chemically resistant seals; consult the Material Compatibility Matrix (MCM-2024 Rev. B) for solvent-specific exposure limits.
Is gradient delay volume characterized and compensatable?
Gradient dwell volume is instrument-specific and measured per installation; the firmware supports user-input dwell correction to align observed gradient elution with programmed timepoints.
Does the pump support remote start/stop and fault reporting via digital I/O?
Yes—standard 24 VDC dry-contact inputs/outputs allow integration with PLCs and safety interlock circuits per IEC 61508 SIL1 requirements.
Are calibration certificates provided with each unit?
A factory-as-tested performance report (including flow accuracy, pressure linearity, and pulse amplitude at three load points) is supplied; UKAS-accredited calibration is available as an optional service.