Sanotac LP0310 High-Pressure Dual-Piston Constant-Flow Pump (3000 mL/min, 10 MPa)

Overview

The Sanotac LP0310 is a high-performance dual-piston constant-flow pump engineered for demanding industrial and laboratory fluid delivery applications requiring precise, stable, and corrosion-resistant high-pressure operation. Designed around Couette-type parallel dual-piston architecture with floating piston mechanics and cam-profiled drive compensation, the LP0310 delivers consistent volumetric displacement across its full dynamic range—from 0.1 mL/min to 3000 mL/min—while maintaining pressure stability up to 10 MPa (1450 psi). Its operating principle relies on synchronized reciprocating motion of two independently driven pistons, combined with real-time solvent compressibility correction and multi-point flow calibration algorithms. This architecture minimizes dead volume, eliminates flow discontinuity at stroke transitions, and ensures repeatable delivery under variable backpressure conditions typical in supercritical fluid processing, catalytic reactor feeding, and high-flow preparative chromatography systems.

Key Features

• Dual-piston parallel pumping mechanism with floating piston design reduces seal wear and extends service life of high-pressure sealing components.
• Microprocessor-based control system supports programmable flow profiles, gradient generation (isocratic, linear, step, and composite gradients), and automatic solvent compressibility compensation.
• Low-pressure pulsation performance (≤0.5 MPa) achieved via optimized cam curve profiling and active electronic flow pulse suppression.
• Chemically inert wetted path constructed from 316L stainless steel, sapphire check valves, PTFE seals, and ceramic piston components—compatible with aggressive solvents, acids, bases, and supercritical CO₂.
• Open communication protocol (RS232/RS485) enables seamless integration with third-party chromatography data systems (CDS), LIMS, or custom SCADA platforms without proprietary driver dependencies.
• Front-panel interface with 256×64 backlit LCD provides real-time monitoring of flow rate, pressure, gradient status, error codes, and user-programmable method storage (10 built-in methods).

Sample Compatibility & Compliance

The LP0310 is validated for use with low-to-medium viscosity liquids (up to 500 cP) including organic solvents (acetonitrile, methanol, THF), aqueous buffers, ionic liquids, catalyst slurries, and supercritical fluids. Its wetted materials comply with USP Class VI biocompatibility standards for elastomers and meet ASTM F2136 for metallic component corrosion resistance in chloride-rich environments. While not certified for GMP production environments out-of-the-box, the pump’s deterministic control logic, audit-trail-capable firmware (via optional logging module), and deterministic gradient reproducibility support alignment with FDA 21 CFR Part 11 requirements when deployed within validated system architectures. It conforms to IEC 61000-6-2 (immunity) and IEC 61000-6-3 (emission) for electromagnetic compatibility.

Software & Data Management

The LP0310 operates natively via front-panel controls but is fully controllable through ASCII-based serial commands over RS232 or RS485 interfaces. Command sets are publicly documented and support full remote configuration of flow rate, gradient slope, hold time, pressure limits, and system diagnostics. When integrated into chromatographic workflows, it interoperates with open-source tools (e.g., Python PySerial scripts) and commercial CDS platforms—including Chromeleon, Empower, and OpenLab—using standard instrument driver frameworks. Optional firmware upgrades enable timestamped event logging (start/stop, pressure alarms, flow deviation alerts) compatible with CSV export for GLP-compliant record retention.

Applications

• Preparative and process-scale liquid chromatography (prep-HPLC, flash chromatography) requiring high-flow mobile phase delivery.
• Catalyst and reagent metering in continuous-flow reactors and fixed-bed catalytic systems.
• Supercritical fluid extraction (SFE) and supercritical fluid chromatography (SFC) where CO₂ or CO₂/co-solvent mixtures demand stable high-pressure delivery.
• Chemical dosing in polymerization, foaming extrusion, and battery electrolyte formulation processes.
• High-throughput screening systems requiring programmable gradient elution across multiple parallel reaction vessels.
• R&D in renewable energy sectors, including hydrogen carrier synthesis, electrocatalyst testing, and biomass conversion reactors.

FAQ

What is the minimum and maximum flow rate supported by the LP0310?
The LP0310 operates from 0.1 mL/min to 3000.0 mL/min in increments of 0.1 mL/min.
Does the pump support gradient elution in chromatographic applications?
Yes—it implements composite gradient capability combining isocratic, linear, and step profiles with user-defined dwell volume compensation.
Can the LP0310 be integrated into an existing LIMS or automated lab platform?
Yes—its open ASCII command protocol and RS232/RS485 interface allow integration without proprietary middleware.
What materials are used in the fluidic path to ensure chemical compatibility?
Wetted components include 316L stainless steel housings, sapphire inlet/outlet check valves, PTFE seals, and ceramic-coated piston surfaces.
Is pressure feedback and overpressure protection included?
The pump monitors outlet pressure continuously and triggers automatic shutdown if preset limits (configurable up to 10 MPa) are exceeded.