Sanotac QP0010 Micro High-Pressure Liquid Chromatography Pump
| Key | Brand: Sanotac |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | OEM/ODM Manufacturer |
| Model | QP0010 |
| Pump Type | Quaternary HPLC Pump |
| Max Pressure | 42 MPa |
| Flow Range | 0.001–10 mL/min |
| Flow Accuracy | ±0.1% |
| Flow Precision (RSD) | ≤0.1% |
| Pump Head Material Options | 316L Stainless Steel or Full PEEK |
| Drive Mechanism | Dual-Piston Series with Floating Piston Design |
| Flow Pulsation | ≤0.1 MPa |
| Display | 256×64 Dot Matrix Backlit LCD |
| Communication Interfaces | RS232/RS485/RS422, USB, Ethernet (wired), Optional Wireless |
| Control Protocols | Custom, Modbus RTU/ASCII, Profibus DP, Profinet |
| Power Supply | 85–264 VAC, 50 Hz |
| Dimensions | 260 × 110 × 110 mm³ |
| Fluidic Connections | 1/16″ Standard Fittings |
| Wetted Materials | 316L SS, Sapphire, PTFE, Ceramic |
Overview
The Sanotac QP0010 Micro High-Pressure Liquid Chromatography Pump is an engineered precision fluid delivery module designed for integration into analytical and process-critical chromatographic systems. Operating on a dual-piston series architecture with floating piston design, the pump delivers stable, pulse-minimized solvent flow across its full range of 0.001–10 mL/min at pressures up to 42 MPa. Its core principle relies on positive displacement via high-precision ceramic-coated sapphire plungers and wear-resistant seals, enabling long-term reproducibility in demanding environments such as UHPLC, ion chromatography (IC), gel permeation chromatography (GPC), post-column derivatization, and clinical diagnostic instrumentation—including hemoglobin A1c analyzers, amino acid analyzers, and IVD platforms compliant with ISO 13485 and FDA 21 CFR Part 820.
Key Features
- Precision Flow Delivery: Achieves ±0.1% flow accuracy and ≤0.1% RSD across the entire range (0.001–9.999 mL/min) through multi-point volumetric calibration and real-time electronic pulse suppression using cam-profile compensation.
- Robust Fluidic Architecture: Wetted path options include corrosion-resistant 316L stainless steel or chemically inert full-PEEK construction—validated for compatibility with aggressive mobile phases including strong acids, bases, and organic solvents.
- Extended Service Life Design: Integrated plunger back-flush function reduces seal wear; floating piston alignment minimizes mechanical stress and thermal drift during extended operation.
- Multi-Protocol Industrial Connectivity: Native support for RS232/485/422, USB, and Ethernet interfaces enables seamless integration into SCADA, DCS, and PLC-based control infrastructures. Protocol stacks include Modbus RTU/ASCII, Profibus DP, Profinet, and user-definable ASCII commands.
- Flexible Control Modes: Supports local keypad operation, analog voltage input (0–5 V / 0–10 V), digital I/O triggering, and remote software control with audit-trail-capable parameter logging—aligned with GLP/GMP data integrity requirements.
Sample Compatibility & Compliance
The QP0010 accommodates diverse sample matrices and eluent chemistries common in regulated laboratories. Its fluidic materials meet USP Class VI biocompatibility standards for PEEK and ASTM F2129 corrosion resistance specifications for 316L SS components. The pump complies with electromagnetic compatibility per IEC 61326-1 and safety standards under IEC 61010-1. When deployed in pharmaceutical QC workflows, it supports method validation per ICH Q2(R2) and can be configured with electronic signatures and 21 CFR Part 11-compliant audit trails when paired with validated host software.
Software & Data Management
Built-in firmware provides real-time visualization of flow rate vs. pressure curves, program progress tracking, and timestamped event logging. Data export is supported in CSV and XLSX formats with optional graphical overlay for comparative analysis. User-defined methods—including linear gradients, step profiles, and custom ramp sequences—can be saved, recalled, and version-controlled. Calibration parameters are stored per method, allowing traceable recalibration without system reconfiguration. Remote monitoring and control are available via optional web-based HMI with TLS-secured communication and role-based access control.
Applications
- Ultra-High-Performance Liquid Chromatography (UHPLC) gradient systems requiring sub-mL/min stability
- Ion chromatography with low-conductivity eluents and suppressed detection
- Gel filtration and size-exclusion chromatography for macromolecular characterization
- Post-column reaction modules for derivatization prior to fluorescence or electrochemical detection
- In vitro diagnostic (IVD) instruments including automated HbA1c analyzers and amino acid quantification platforms
- Lab-scale preparative chromatography and continuous-flow synthesis reactors with closed-loop mass feedback
FAQ
What is the minimum programmable flow increment?
The QP0010 supports flow resolution down to 0.001 mL/min across its full operating range.
Can this pump be used in GMP-regulated environments?
Yes—when integrated with validated software and configured with electronic audit trail, user authentication, and parameter change logging, it meets core requirements of FDA 21 CFR Part 11 and EU Annex 11.
Is PEEK-compatible tubing included with the full-PEEK configuration?
Standard 1/16″ PTFE and PEEK capillary tubing kits are available as optional accessories; wetted-path certification documentation is provided upon request.
Does the pump support gradient mixing internally?
No—the QP0010 is a single-channel quaternary-capable pump; gradient formation requires external low-dead-volume mixing modules or upstream solvent selection valves.
How is pressure protection implemented?
Programmable overpressure cutoff, zero-point pressure offset correction, and real-time pressure deviation alerts ensure system integrity during column blockage or temperature-induced viscosity shifts.
