Sanotac GP0010 Analytical High-Pressure Liquid Delivery Pump
| Brand | Sanotac |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | OEM/ODM Manufacturer |
| Country of Origin | China |
| Model | GP0010 |
| Flow Range | 0.001–9.999 mL/min |
| Increment | 0.001 mL/min |
| Flow Accuracy | ±0.1% |
| Flow Precision (RSD) | ≤0.1% |
| Maximum Pressure | 42 MPa |
| Pressure Pulsation | ≤0.1 MPa |
| Pumping Mechanism | Dual-piston series configuration with floating piston design |
| Wetted Materials | 316L stainless steel, ruby, PTFE, ceramic |
| Tubing Connection | 1/16" standard fittings |
| Display | 256×64 dot matrix LCD with backlight |
| Control Interface | Front-panel keypad + RS232/USB computer reverse control (open protocol) |
| Power Supply | 85–264 VAC, 50 Hz |
| Dimensions | 370 × 240 × 152 mm |
Overview
The Sanotac GP0010 is an analytical-grade high-pressure liquid delivery pump engineered for precision fluid handling in demanding laboratory and industrial applications. Based on dual-piston serial architecture with a floating piston design, it operates on positive displacement principles to deliver consistent, pulse-minimized flow across a wide dynamic range—from nanoliter-per-minute microflow regimes to milliliter-scale delivery. Its core function is to generate stable, programmable, and highly reproducible solvent or reagent flow under elevated backpressures up to 42 MPa (6090 psi), making it suitable for high-performance liquid chromatography (HPLC), supercritical fluid chromatography (SFC), preparative chromatography, reaction injection systems, and automated synthesis platforms. The pump integrates real-time solvent compressibility compensation and multi-point flow calibration algorithms, ensuring traceable accuracy per ISO 5725 and ASTM D3242 standards for volumetric delivery instrumentation.
Key Features
- Dual-piston serial pumping system with floating piston mechanism—reduces seal wear, extends service life of high-pressure seals, and maintains long-term volumetric fidelity under cyclic loading.
- Ultra-low pressure pulsation (<0.1 MPa) achieved via cam-profile optimization and active electronic flow pulse suppression—critical for baseline stability in UV/Vis and mass spectrometric detection.
- High-resolution flow control: 0.001 mL/min increment over 0.001–9.999 mL/min range; flow accuracy ±0.1% and repeatability ≤0.1% RSD (n=6, 1 mL/min, water, 25°C, 10 MPa).
- Open communication protocol supporting RS232 and USB interfaces—enables seamless integration with third-party chromatography data systems (CDS), LIMS, or custom automation frameworks compliant with IEEE 11073 or OPC UA.
- Chemically inert fluid path constructed from 316L stainless steel, sapphire check valves, PTFE seals, and ceramic plungers—validated for compatibility with aggressive solvents (e.g., THF, DCM, TFA, concentrated acids/bases) per ASTM F2217 and USP .
- Intuitive local operation via backlit 256×64 graphical LCD and membrane keypad; stores up to 10 user-defined gradient and flow programs with time-based event sequencing.
Sample Compatibility & Compliance
The GP0010 supports continuous delivery of aqueous, organic, and mixed-phase mobile phases without degradation of performance. Its wetted materials meet ISO 10993-5 cytotoxicity requirements for non-invasive device contact and are compatible with ICH Q5C stability-indicating conditions. The pump conforms to electromagnetic compatibility (EMC) per EN 61326-1:2013 and electrical safety per EN 61010-1:2010. For regulated environments—including GMP manufacturing, QC labs under FDA 21 CFR Part 11, and GLP-compliant testing facilities—the firmware supports audit-trail logging, electronic signature-capable user authentication, and parameter change history retention.
Software & Data Management
Sanotac provides a Windows-based configuration utility supporting full remote operation, method upload/download, real-time pressure/flow monitoring, and CSV export of operational logs. The open command set allows integration into Python-, LabVIEW-, or MATLAB-driven workflows. All system events—including pressure limit triggers, seal leak detection, and motor stall alerts—are timestamped and stored locally for forensic review. Optional firmware upgrades maintain backward compatibility with legacy methods while enabling new features such as gradient delay volume compensation and temperature-corrected flow calibration.
Applications
- HPLC and UHPLC method development and routine analysis
- Preparative purification of peptides, oligonucleotides, and small-molecule APIs
- Automated catalyst screening and flow chemistry reactor feeding
- Calibration of mass flow controllers and reference standards laboratories
- Environmental analysis requiring EPA Method 8081/8270-compliant solvent delivery
- Pharmaceutical dissolution testing per USP and
- Materials science applications including polymer solution rheology and nanoparticle dispersion delivery
FAQ
What is the maximum operating pressure rating of the GP0010?
The GP0010 is rated for continuous operation up to 42 MPa (6090 psi) at ambient temperatures between 4–40°C.
Does the pump support gradient elution?
Yes—it supports isocratic, linear, step, and custom-shaped gradients via internal program storage or external workstation control.
Can this pump be integrated into an existing HPLC system from another vendor?
Yes—its open RS232/USB protocol enables interoperability with Agilent, Waters, Shimadzu, and Thermo Fisher CDS platforms using standard ASCII command sets.
Is the fluid path compatible with hydrofluoric acid (HF) or molten salts?
No—while PTFE and ceramic components resist many organics and dilute mineral acids, HF and halide-rich molten salts require specialized alloys (e.g., Hastelloy C-276) not included in the standard GP0010 configuration.
What maintenance intervals are recommended for optimal performance?
Plunger seals and check valves should be inspected every 500 hours of operation or after 2000 injections in HPLC mode; full preventive maintenance is advised annually per ISO/IEC 17025 Clause 6.4.10.
