Luer Connector, Model 45500-00
| Origin | USA |
|---|---|
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | 45500-00 |
| Pricing | Available Upon Request |
Overview
The Luer Connector Model 45500-00 is a precision-engineered fluidic interface component designed for reliable, leak-tight connections in peristaltic pump systems and other low-to-medium pressure laboratory fluid handling applications. Based on the ISO 594-1 and ISO 594-2 standards for conical fittings, this connector features a standardized 6% taper (Luer taper) with nominal internal and external diameters of 6.0 mm at the base and 4.8 mm at the tip. It operates via a friction-based locking mechanism—either slip-fit (non-locking) or screw-type (Luer lock)—to ensure secure coupling between tubing, syringes, valves, and pump heads. Its primary function is to maintain consistent flow path integrity while minimizing dead volume, pressure drop, and contamination risk during continuous or intermittent fluid transfer operations.
Key Features
- ISO-compliant 6% Luer taper geometry for universal compatibility with standard laboratory consumables including syringes, filters, chromatography columns, and peristaltic pump tubing adapters.
- Manufactured from medical-grade polypropylene (PP), offering chemical resistance to common aqueous buffers, alcohols, and dilute acids/bases; suitable for repeated sterilization via autoclaving (121 °C, 20 min).
- Dimensionally stable under mechanical compression—designed to withstand axial insertion forces up to 35 N without deformation or thread stripping (for Luer lock variants).
- Low dead volume (< 5 µL) and smooth internal bore surface finish (Ra < 0.8 µm) to reduce sample carryover and support accurate volumetric delivery in QC and analytical workflows.
- Traceable lot numbering and RoHS/REACH compliance documentation provided with each shipment for GLP and GMP-regulated environments.
Sample Compatibility & Compliance
This Luer connector supports a wide range of fluid types—including cell culture media, HPLC mobile phases, buffer solutions, and viscous reagents up to 500 cP—when used within its rated pressure limit of ≤100 kPa (14.5 psi) static pressure. It is compatible with silicone, Tygon®, PharMed® BPT, and PVC peristaltic pump tubing (ID 0.8–3.2 mm). The component meets ISO 594-1:2015 (taper dimensions), ISO 594-2:2015 (locking torque requirements), and USP for elastomeric closures. For regulated laboratories, it supports audit-ready documentation packages including material certificates, biocompatibility data (USP Class VI), and extractables testing reports upon request.
Software & Data Management
As a passive mechanical interface, the Model 45500-00 does not incorporate embedded electronics or firmware. However, it integrates seamlessly into digitally controlled peristaltic pump systems (e.g., Watson-Marlow, Cole-Parmer, and Masterflex platforms) where connection integrity directly impacts flow accuracy and system-level error logging. When deployed in automated liquid handling workflows governed by FDA 21 CFR Part 11–compliant software, its use is documented in instrument configuration records and maintenance logs to satisfy traceability requirements for calibration and change control procedures.
Applications
- Connecting inlet/outlet lines to peristaltic pump heads in continuous-flow synthesis, fermentation feed control, and dialysis systems.
- Interfacing syringe pumps with microfluidic chips or capillary electrophoresis modules requiring precise low-volume dispensing.
- Adapting filtration manifolds, vacuum manifolds, and gas sampling loops in environmental and pharmaceutical QC labs.
- Enabling modular reconfiguration of multi-channel peristaltic pump arrays in method development studies compliant with ICH Q2(R2) guidelines.
- Supporting single-use bioprocessing assemblies where rapid, sterile connector exchange is required between upstream and downstream unit operations.
FAQ
What is the maximum recommended operating pressure for this Luer connector?
The connector is rated for continuous use at pressures up to 100 kPa (14.5 psi); transient spikes up to 150 kPa are permissible for durations under 5 seconds.
Is this connector suitable for sterile filtration applications?
Yes—when assembled with sterile-filtered tubing and used with pre-sterilized components, it maintains aseptic integrity; validation protocols for filter integrity testing (e.g., bubble point or diffusion tests) remain unaffected.
Can it be reused after autoclaving?
Yes—polypropylene construction allows for up to 50 autoclave cycles at 121 °C without measurable dimensional drift or seal degradation, provided mechanical stress during installation is controlled.
Does it comply with FDA or EU MDR requirements?
While the component itself is not a medical device, its materials and manufacturing process conform to FDA 21 CFR 177.1520 (food-contact polymers) and EU Regulation (EC) No 1935/2004, supporting its use in Class I and IIa device manufacturing environments.
How is lot traceability managed for quality assurance?
Each package includes a unique lot number linked to raw material batch records, injection molding parameters, and dimensional inspection reports—available electronically upon request for internal QA audits.
