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Cole-Parmer CPC Quick-Connect Fitting, Model 06363-55

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Brand Cole-Parmer
Origin USA
Distributor Type Authorized Distributor
Origin Category Imported
Model 06363-55
Pricing Available Upon Request

Overview

The Cole-Parmer CPC Quick-Connect Fitting (Model 06363-55) is a precision-engineered fluidic coupling component designed for rapid, leak-tight connection and disconnection of tubing in peristaltic pump systems and other low-to-medium pressure laboratory fluid handling applications. Unlike threaded or barbed fittings, CPC fittings utilize a push-to-connect mechanism with an integrated stainless-steel collet and EPDM or silicone sealing elements—enabling secure engagement under typical peristaltic pump operating pressures (up to 100 psi / 6.9 bar, depending on tubing material and size). This design eliminates the need for tools, reduces assembly time, and minimizes risk of overtightening or tubing deformation—critical factors in maintaining flow consistency and preventing sample cross-contamination in QC, bioprocessing, and analytical workflows.

Key Features

  • Tool-free operation: One-handed push-and-lock engagement with audible click feedback for positive confirmation.
  • Chemical compatibility: Sealing materials (EPDM standard; optional silicone or Viton variants) rated for compatibility with aqueous buffers, alcohols, mild acids/bases, and common organic solvents used in lab-scale pumping.
  • Tubing retention: Stainless-steel collet provides uniform radial compression across tubing OD, ensuring consistent grip without kinking or flattening—preserving peristaltic pump tube integrity and service life.
  • Pressure rating: Validated for continuous use up to 100 psi (6.9 bar) at 23°C with compatible tubing (e.g., PharMed BPT, Tygon® 2001, or Norprene®).
  • Reusability: Designed for ≥1000 mating cycles without degradation in sealing performance or mechanical integrity when used within specified operating conditions.
  • Traceable documentation: Each batch conforms to ISO 9001 manufacturing controls; RoHS and REACH compliance documented per EU Directive 2011/65/EU and Regulation (EC) No. 1907/2006.

Sample Compatibility & Compliance

The 06363-55 fitting is dimensionally optimized for 1/4″ (6.35 mm) OD tubing—a standard size widely used with medium-flow peristaltic pump heads (e.g., Masterflex L/S® 16 or I/P® 16 series). It supports single-use and reusable tubing configurations and maintains seal integrity across temperature ranges from –40°C to +100°C. While not a regulated medical device, its construction and material certifications align with general laboratory good practice (GLP) requirements for equipment used in method validation, stability testing, and process transfer. Where applicable in regulated environments (e.g., pharmaceutical QC labs), integration into systems subject to FDA 21 CFR Part 11 requires validation of the entire fluid path—including fitting installation torque equivalence, leak integrity, and cleaning verification protocols.

Software & Data Management

As a passive mechanical component, the CPC Quick-Connect Fitting does not incorporate electronics, firmware, or embedded software. Its role in data integrity lies in operational reliability: consistent connection repeatability contributes directly to volumetric accuracy and flow stability in automated peristaltic pump systems. When deployed with programmable pumps (e.g., Cole-Parmer Masterflex I/P® or IPC® series), the fitting supports traceable fluid path configuration—enabling audit-ready records of tubing type, replacement date, and connection point mapping within LabVantage, Empower, or custom LIMS environments. Documentation packages include material certificates of conformance (CoC) and dimensional inspection reports upon request.

Applications

  • Peristaltic pump manifold assembly for multi-channel reagent dispensing in ELISA, cell culture media preparation, and buffer exchange systems.
  • In-line filtration and sterile transfer setups where rapid tubing changeout between batches is required.
  • Modular fluidic interconnections in custom-built analytical sample introduction systems (e.g., ICP-MS autosampler interfaces, HPLC gradient mixing modules).
  • Bioreactor feed/perfusion lines requiring frequent sterilization-in-place (SIP) and tubing replacement without disassembly of fixed manifolds.
  • Educational lab kits demonstrating fluid circuit design principles, flow control, and system modularity.

FAQ

What tubing sizes are compatible with model 06363-55?
This fitting is specified for 1/4″ (6.35 mm) outer diameter tubing. Inner diameter varies based on wall thickness; common pairings include 1/8″ ID (3.2 mm) and 3/16″ ID (4.8 mm) tubing.
Can this fitting be used with aggressive solvents like acetone or THF?
Standard EPDM seals are not recommended for ketones or chlorinated hydrocarbons. For such applications, specify silicone or fluorocarbon (Viton®) seal variants—available under custom part numbers.
Is the fitting autoclavable?
No. The EPDM seal and plastic housing are not rated for repeated steam sterilization. For SIP-compatible applications, consider alternative metal-bodied CPC variants or validated disposable fluid path solutions.
Does Cole-Parmer provide installation validation support?
Yes—application engineers can supply torque-equivalence guidelines, leak test protocols (per ASTM F2391), and tubing insertion depth specifications to support IQ/OQ documentation.

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