Masterflex Reglo Miniflex Digital Multifunction Peristaltic Pump Model 78018-40

Overview

The Masterflex Reglo Miniflex Digital Multifunction Peristaltic Pump Model 78018-40 is an engineered solution for precise, repeatable, and low-flow fluid handling in analytical laboratories, bioprocessing workflows, and quality control environments. Based on the positive displacement principle of peristaltic pumping—where rollers compress flexible tubing to create a sealed, contamination-free fluid path—the 78018-40 delivers high reproducibility without requiring valves, seals, or wetted pump components beyond the tubing itself. Its compact benchtop footprint (147 × 229 × 157 mm) and robust ABS/aluminum chassis support integration into automated workstations, laminar flow hoods, and modular process skids. The pump operates across an exceptionally wide dynamic range—from 0.004 mL/min at 0.1 rpm to 365 mL/min at 350 rpm—enabling applications from nanoliter-scale reagent dosing to continuous media delivery in cell culture systems.

Key Features

• 5-inch capacitive TFT/RGB touchscreen interface with 1280 × 720 resolution, offering intuitive navigation, real-time parameter visualization, and multi-angle viewing under varied lab lighting conditions.
• Dual-mode dispensing architecture: volume-based (with programmable batch count, interval timing, and pause duration) and time-based (with adjustable run/stop cycles), both supporting drip prevention and speed ramping to minimize overshoot and sample loss.
• Miniflex L/S® pump head with 180° occlusion angle and self-lubricating thermoplastic polyester rollers ensures uniform compression, extended tubing life, and reliable backflow prevention up to 3 bar (45 psi).
• Three-tier user access control (Operator, Supervisor, Administrator) enables role-based parameter locking, method protection, and compliance with internal SOPs and regulatory frameworks such as FDA 21 CFR Part 11 when paired with MasterflexLive audit trails.
• Integrated safety interlocks: automatic motor stop upon pump head opening, thermal overload protection, and stall detection via current monitoring.
• Full I/O flexibility—including RJ45 Ethernet, onboard Wi-Fi, USB firmware update port, and DB-25 analog/digital interface (0–10 V, 4–20 mA, TTL start/stop/direction)—supports PLC synchronization, SCADA integration, and centralized fleet management.

Sample Compatibility & Compliance

The 78018-40 accepts standard L/S®-series silicone, Viton®, C-Flex®, and PharMed® BPT tubing sizes (L/S 13, 14, 16, and 25), enabling chemical compatibility mapping across aqueous buffers, organic solvents, acids, bases, and shear-sensitive biological fluids. No fluid contact occurs with metal or elastomeric pump components other than the tubing—eliminating cross-contamination risk and simplifying cleaning validation. The device is CE-marked and UL-listed, conforming to IEC 61000-6-2 (EMC immunity) and IEC 61000-6-4 (EMC emissions). When operated with MasterflexLive cloud connectivity and configured with timestamped operation logs, event history, and user authentication, the system supports GLP and GMP documentation requirements, including electronic record integrity per ALCOA+ principles.

Software & Data Management

MasterflexLive—a secure, ISO 27001-aligned cloud platform—provides remote configuration, real-time telemetry, and historical analytics for individual or networked Reglo pumps. Users can adjust speed, dispense volume, cycle count, and ramp profiles from any web-enabled device; receive push notifications for errors (e.g., tubing fatigue, flow deviation >±1.5%), power interruptions, or maintenance alerts; and export CSV-formatted logs for trending analysis or regulatory submission. Firmware updates are delivered over-the-air or via USB, ensuring long-term compatibility with evolving IT infrastructure and cybersecurity policies. Local data retention on the pump’s embedded memory includes last 100 operational events with timestamps, user IDs, and parameter snapshots—fully traceable without cloud dependency.

Applications

• Automated liquid handling in HPLC mobile phase delivery, IC eluent generation, and autosampler rinsing protocols.
• Controlled feeding of nutrients, inducers, or pH-adjusting agents in fed-batch bioreactors and microbioreactor arrays.
• Precision metering of standards, dyes, or calibration solutions in clinical chemistry analyzers and environmental testing instruments.
• Low-shear transfer of primary cells, organoids, or extracellular vesicles where laminar flow and minimal pulsation are critical.
• Integration into ISO 17025-accredited testing labs for volumetric verification of pipettes and burettes using gravimetric or conductivity-based flow calibration methods.

FAQ

What tubing sizes are compatible with the Miniflex pump head?
The 77220-20 and 77220-30 Miniflex heads accept L/S® tubing sizes 13, 14, 16, and 25—covering inner diameters from 0.13 mm to 3.2 mm.
Does the pump support bidirectional flow?
Yes—the integrated reversible DC motor allows forward/reverse operation, programmable via touchscreen or MasterflexLive for backflush or priming routines.
Can the pump be validated for use in regulated pharmaceutical manufacturing?
When deployed with MasterflexLive audit logging, user access controls, and electronic signature capability (via optional enterprise license), the 78018-40 meets foundational requirements for use in GMP environments per Annex 11 and USP .
Is analog signal input supported for external speed control?
Yes—0–10 VDC and 4–20 mA inputs are available on the DB-25 connector for seamless integration with PID controllers, DAQ systems, or legacy automation hardware.
What is the maximum allowable backpressure during operation?
The pump maintains rated accuracy up to 3 bar (45 psi) with appropriate tubing selection; exceeding this may reduce flow linearity and accelerate tubing wear.