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Masterflex 95664-14 High-Pressure Peristaltic Pump Head

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Brand Cole-Parmer
Origin USA
Manufacturer Type Authorized Distributor
Origin Category Imported
Model 95664-14
Pricing Upon Request
Rotor/Bearing/Spindle/Disc Material 316 Stainless Steel
Bed Material Polyphenylsulfone (PPS)
Max. Outlet Pressure 10.2 bar (Pharmed 14HP tubing)
Flow Range 0.006–30 mL/min (at 0.02–100 rpm)
Tubing Length per Roll 7.6 m
ATEX Certification II 3G c II C T6 (for 77250-82 variant)

Overview

The Masterflex 95664-14 High-Pressure Peristaltic Pump Head is an engineered component designed for integration into precision fluid handling systems requiring sustained pressure delivery and high chemical compatibility. Based on the fundamental principle of peristaltic displacement—where rollers compress elastomeric tubing against a rigid occlusion bed to generate unidirectional flow—the 95664-14 head delivers controlled, pulse-free, and contamination-free transfer without exposing internal mechanical parts to the process fluid. Its architecture supports operation with Pharmed® 14HP high-pressure tubing, enabling maximum outlet pressures up to 10.2 bar while maintaining structural integrity and dimensional stability across extended duty cycles. Unlike standard pump heads, this model features a robust 316 stainless steel rotor assembly—including spindle, bearing housing, and disc—as well as a chemically resistant polyphenylsulfone (PPS) occlusion bed, ensuring long-term reliability in aggressive solvent environments and elevated temperature applications.

Key Features

  • High-pressure capability: Rated for continuous operation at up to 10.2 bar with Pharmed 14HP tubing (model 95664-14), supporting demanding applications such as HPLC mobile phase delivery, high-viscosity reagent dosing, and pressurized bioreactor feed systems.
  • Corrosion-resistant construction: All rotating and load-bearing components—including rotor, spindle, disc, and bearings—are fabricated from ASTM F138-certified 316 stainless steel, providing resistance to chloride-induced pitting and crevice corrosion.
  • Chemically inert occlusion bed: Precision-machined PPS (polyphenylsulfone) bed ensures dimensional stability at temperatures up to 180 °C and compatibility with strong acids, bases, and organic solvents including acetone, THF, and DMSO.
  • Optimized roller geometry: Patented dual-roller design minimizes tubing fatigue and extends service life of high-performance tubing by distributing compression force more evenly across the occlusion zone.
  • Modular integration: Designed for seamless mounting onto Masterflex I/P or E/S series drive units; compatible with analog and digital speed controllers featuring 0–10 VDC or 4–20 mA input interfaces.

Sample Compatibility & Compliance

The 95664-14 pump head is validated for use with Masterflex Pharmed HP series tubing (95664-14, -15, -16, -24), each selected for specific pressure–flow trade-offs and chemical exposure profiles. Tubing selection must align with ISO 8536-4 (infusion sets), USP (biological reactivity), and FDA-compliant manufacturing under 21 CFR Part 211 (for pharmaceutical-grade applications). The optional 77250-82 variant carries ATEX certification (II 3G c II C T6), permitting safe deployment in Zone 2 hazardous locations where flammable vapors may be present during intermittent operation. All configurations comply with RoHS 2015/863/EU and REACH SVHC screening requirements.

Software & Data Management

When paired with Masterflex E/S-series programmable drives or third-party PLC-controlled motion systems, the 95664-14 enables traceable, auditable fluid delivery protocols. Drive firmware supports time-stamped flow logs, ramped acceleration profiles, and error-triggered shutdown events—features essential for GLP and GMP environments. Integration with LabVIEW™, MATLAB® Instrument Control Toolbox, or OPC UA–compliant SCADA platforms allows real-time parameter monitoring and remote calibration verification. Audit trails meet FDA 21 CFR Part 11 requirements when deployed with electronic signature-enabled control software and secure user access tiers.

Applications

  • High-pressure liquid chromatography (HPLC) and UHPLC mobile phase delivery where backpressure tolerance exceeds 80 bar at the column inlet.
  • Continuous feeding of viscous polymer solutions (e.g., PEG, hyaluronic acid) in bioprocess scale-up studies.
  • Controlled dosing of caustic cleaning agents (e.g., NaOH, peracetic acid) in CIP systems compliant with ASME BPE-2022 standards.
  • Automated sampling loops in environmental water analysis systems requiring precise sub-mL aliquoting under elevated line pressure.
  • Pressurized nutrient delivery in perfusion-based cell culture bioreactors operating at 0.5–2.0 bar gauge pressure.

FAQ

What tubing sizes are compatible with the 95664-14 pump head?

The 95664-14 is optimized exclusively for Pharmed 14HP tubing (ID 0.76 mm, OD 2.39 mm); other HP variants (15HP, 16HP, 24HP) require corresponding pump heads (95664-15, 95664-16, 95664-24) due to differing occlusion geometries.
Can this pump head be used with non-Masterflex tubing?

While mechanically possible, using non-certified tubing voids pressure ratings and compromises compliance with ISO 8536-4 and USP ; Masterflex does not validate performance or safety with third-party tubing.
Is the 95664-14 suitable for sterile applications?

Yes—when assembled with gamma-irradiated Pharmed HP tubing (sterility assurance level 10⁻⁶) and installed in ISO Class 5 laminar flow hoods, it meets requirements for aseptic fluid transfer in cell therapy manufacturing.
Does the pump head include a drive motor?

No—the 95664-14 is a standalone pump head module; it must be mounted onto a compatible Masterflex drive unit (e.g., I/P 77400-60 or E/S 77400-70) to function.
How often should the rotor bearings be serviced?

Under continuous operation at ≤80% of max rated speed and ambient temperatures <40 °C, the sealed 316 SS bearings require no scheduled maintenance for ≥15,000 hours; visual inspection is recommended every 6 months in corrosive atmospheres.

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