Masterflex B/T Series Peristaltic Pump (Fixed-Speed and Variable-Speed Models)

Overview

The Masterflex^® B/T^® Series Peristaltic Pump (Model 77111-67) is an industrial-grade, variable-speed peristaltic pump engineered for high-flow, high-reliability fluid transfer in demanding laboratory, pilot-scale, and production environments. Operating on the principle of positive displacement via roller compression of elastomeric tubing, this pump delivers precise, pulse-free flow without fluid contact with mechanical components—ensuring contamination-free handling of shear-sensitive, viscous, abrasive, or sterile media. With a maximum flow capacity of 42 L/min (11.1 GPM) and a speed range of 12–321 rpm, the B/T platform supports applications requiring both volumetric accuracy and robust throughput, including bioprocessing, chemical dosing, fermentation feed control, and continuous analytical sample delivery.

Key Features

• High-capacity motor (½ hp / 0.37 kW) optimized for sustained operation with viscosities up to 10,000 cP
• IP56-rated motor housing—dust-tight and protected against powerful water jets—enabling washdown-capable installation in regulated manufacturing areas
• Rapid-Load^® pump head design minimizes tubing installation time and eliminates “tube wrapping” during operation through precision-machined occlusion geometry
• Integrated safety interlock: power is automatically cut when the pump head cover is opened, complying with IEC 61800-5-2 functional safety requirements
• Bidirectional motor operation supports forward/reverse pumping for tube cleaning, priming, and backflush protocols
• Digital speed control with ±5% repeatability across full speed range; compatible with analog 0–10 VDC or 4–20 mA external signals for PLC integration
• Factory-calibrated Tygon^® E-LFL B/T 91 tubing (included) certified for USP Class VI, FDA 21 CFR 177.2600, and EC 1935/2004 compliance

Sample Compatibility & Compliance

The B/T 77111-67 accommodates a broad spectrum of fluid types—including cell cultures, protein solutions, polymer emulsions, slurries, and aggressive solvents—without risk of cross-contamination or catalytic degradation. Its tubing-based architecture eliminates valves, seals, and wetted metal parts, making it ideal for GLP/GMP workflows where validation and traceability are critical. The system meets ATEX Zone 2 (EEx II 3G c IIC T6) and NEC Class I, Division 2 (Groups A, B, C, D, T6) standards for use in potentially explosive atmospheres. All electrical components comply with UL 61010-1 and CSA C22.2 No. 61010-1 for laboratory equipment safety. Tubing selection adheres to ISO 8536-4 for infusion sets and ASTM D2990 for elastomer aging performance.

Software & Data Management

While the 77111-67 operates as a standalone analog-controlled unit, it integrates seamlessly into automated systems via its 0–10 VDC speed input and direction control terminals. For enhanced process documentation, optional digital controllers (e.g., Masterflex Model 77111-70/77) provide RS-232/RS-485 communication, real-time flow monitoring, programmable dispensing by volume or time, and audit-trail-enabled operation compliant with FDA 21 CFR Part 11 requirements. Controller firmware supports configurable start/stop sequences, ramp profiles, and fault logging—including overtemperature, stall detection, and tubing wear alerts. All configurations support IQ/OQ documentation templates aligned with ISO/IEC 17025 calibration frameworks.

Applications

• Continuous feeding of nutrient media in mammalian cell culture bioreactors
• Accurate metering of catalysts or inhibitors in fine chemical synthesis
• Recirculation and filtration loops in pharmaceutical water-for-injection (WFI) systems
• Automated sampling for online HPLC or ICP-MS analysis with minimal carryover
• Transfer of shear-thinning hydrogels in biomaterial 3D printing prep stations
• Sanitary CIP (clean-in-place) circulation with caustic or acidic solutions

FAQ

What tubing sizes and materials are validated for use with the B/T 77111-67?
Masterflex certifies Tygon® E-LFL B/T 91 (ID 3.2 mm, OD 6.4 mm) as standard. Alternative chemically resistant options include PharMed® BPT and Norprene® A-60-F, all available in ISO-certified lot traceability.

Can the pump be integrated into a SCADA or MES environment?
Yes—via analog signal interface (0–10 VDC) or optional digital controller with Modbus RTU protocol support for seamless data exchange with supervisory systems.

Is validation support available for GMP installations?
Masterflex provides IQ/OQ protocol templates, factory calibration certificates (NIST-traceable), and material compliance dossiers for all wetted components.

How often should tubing be replaced under continuous operation?
Typical service life ranges from 100–500 hours depending on speed, pressure, and fluid abrasiveness; built-in wear indicators and predictive maintenance logs are available with digital controller upgrades.