Cole-Parmer Masterflex L/S PTFE Peristaltic Pump Head (Model 77390-00)

Overview

The Cole-Parmer Masterflex L/S PTFE Peristaltic Pump Head (Model 77390-00) is a chemically inert, precision-engineered peristaltic pump head designed for demanding laboratory and industrial fluid transfer applications where compatibility with aggressive solvents, high-purity requirements, and pressure resilience are critical. Based on the proven Masterflex L/S modular drive platform, this pump head employs a six-roller, adjustable occlusion mechanism to compress PTFE tubing—ensuring repeatable flow control while minimizing mechanical stress on the tubing. Unlike elastomeric pump heads, the PTFE-compatible design eliminates chemical degradation pathways by restricting wetted contact exclusively to high-purity polytetrafluoroethylene (PTFE), including tubing, valve components (in optional diaphragm variants), and housing surfaces. The principle of peristalsis—where rollers sequentially compress flexible tubing to displace fluid—is maintained, but with enhanced chemical resistance and pressure capability up to 6.9 bar continuous, making it suitable for pressurized filtration, reagent dosing into closed systems, and high-integrity sampling protocols.

Key Features

• Chemically inert wetted path: PTFE tubing is the sole fluid-contact component; housing combines anodized aluminum and acetal for structural integrity and corrosion resistance.
• Six-roller geometry with fine-adjustable occlusion: Enables precise tuning between pressure generation (tight occlusion) and tubing service life (loose occlusion), supporting both high-head and extended-duty operation.
• Stainless steel rotor assembly: Ensures dimensional stability, torque transmission fidelity, and long-term resistance to environmental oxidation or solvent exposure.
• Modular L/S drive compatibility: Designed for integration with any Masterflex L/S series drive accommodating two or more pump heads (minimum motor rating: 0.1 hp).
• Validated pressure performance: Capable of sustaining 6.9 bar continuous outlet pressure and 2.4 m suction lift—exceeding typical elastomer-based peristaltic heads.
• Traceable configuration: Supplied with one 38 cm length of Masterflex L/S 35 PTFE tubing (2.4 × 4.0 mm I.D./O.D.) and mounting hardware for immediate installation and verification.

Sample Compatibility & Compliance

This pump head is explicitly intended for use with Masterflex L/S PTFE tubing (e.g., part numbers 77390-50, 77390-60) and is incompatible with silicone, Viton®, or other elastomeric tubing due to differential compression modulus and thermal expansion characteristics. Its all-PTFE fluid path ensures compatibility with concentrated mineral acids (e.g., HNO₃, H₂SO₄), strong bases (e.g., 50% NaOH), halogenated solvents (e.g., chloroform, carbon tetrachloride), and polar aprotic media (e.g., DMF, DMSO, THF). It meets material compliance requirements for ISO 10993-5 (cytotoxicity) and USP Class VI testing when used with certified PTFE tubing. While not intrinsically rated for explosion-proof environments, its non-sparking housing materials support use in Class I, Division 2 hazardous locations when paired with appropriately certified drives. No regulatory certification (e.g., FDA 21 CFR Part 11) applies directly to the pump head itself; however, when integrated into validated GxP workflows—including those aligned with ASTM D3923 (liquid transfer accuracy) or ISO 8573-1 (compressed air purity)—its reproducible occlusion behavior supports audit-ready documentation of flow parameters.

Software & Data Management

As a mechanically actuated, analog pump head, the 77390-00 does not incorporate embedded electronics or digital interfaces. Flow rate is governed solely by drive motor speed (0.02–400 rpm) and tubing dimensions—enabling direct integration with programmable logic controllers (PLCs), LabVIEW-based DAQ systems, or third-party PID controllers via 0–10 VDC or 4–20 mA analog input signals. When used with Masterflex L/S drives equipped with encoder feedback (e.g., models 77400-20, 77400-40), rotational speed can be logged with ±0.1% repeatability over time, supporting GLP-compliant batch records. Audit trails for speed setpoints, runtime duration, and occlusion adjustments must be maintained externally through drive-level firmware or supervisory SCADA systems. Firmware updates, calibration certificates, and traceable speed verification reports are available through Cole-Parmer’s technical support portal upon request.

Applications

• High-purity reagent delivery in semiconductor wafer cleaning and photolithography lines, where metal ion leaching must remain below 1 ppt.
• Acid digestion sample introduction for ICP-MS and ICP-OES, resisting HF/HNO₃ mixtures at elevated temperatures.
• Continuous filtration of aggressive process streams in pharmaceutical API synthesis, including reaction quenching and work-up solvent transfers.
• Controlled dosing of catalysts or initiators into pressurized polymerization reactors (up to 6.9 bar).
• Environmental monitoring: Acidified preservation of aqueous samples during automated field collection, maintaining analyte stability for EPA Method 200.8 compliance.
• In-line sparging of corrosive gases (e.g., Cl₂, SO₂) into PTFE-lined absorption loops for stack emission analysis.

FAQ

Is this pump head compatible with non-PTFE tubing?
No. Only Masterflex L/S PTFE tubing (e.g., 77390-50, 77390-60) may be used. Substitution with silicone, Norprene®, or Viton® tubing will result in premature failure, inaccurate flow, and potential contamination.
What is the maximum allowable inlet vacuum when operating at full occlusion?
The pump head supports up to 2.4 m suction lift under ambient conditions. Inlet vacuum must not exceed −0.23 bar (−23 kPa) to prevent tubing collapse or loss of prime.
Can this head be sterilized in place (SIP) using steam?
No. PTFE tubing is not rated for autoclave or SIP cycles. For sterile applications, use gamma-irradiated, pre-sterilized PTFE tubing assemblies and replace after each use.
Does the pump head include tubing wear compensation?
No. Occlusion adjustment is manual and static. Users must periodically verify and re-tighten occlusion as tubing elasticity degrades over time—typically every 200–500 hours of operation depending on speed and pressure load.
What drive models are certified for use with this head at 400 rpm?
Masterflex L/S models 77400-40 (400 rpm max), 77400-60 (600 rpm max), and 77400-80 (800 rpm max) are mechanically rated for full-speed operation with this head when properly mounted and thermally managed.