Cole-Parmer PX10-600 High-Flow Peristaltic Pump

Overview

The Cole-Parmer PX10-600 High-Flow Peristaltic Pump is an industrial-grade fluid transfer solution engineered for continuous, contamination-free operation in demanding laboratory, pilot-scale, and light process environments. Based on the positive displacement peristaltic principle—where rollers compress flexible tubing against a curved housing to generate flow—the PX10-600 eliminates fluid contact with mechanical components, ensuring absolute isolation of the pumped medium. This design inherently prevents cross-contamination, eliminates the need for valves or seals, and supports sterile, shear-sensitive, abrasive, or highly viscous media handling without degradation. The pump integrates a brushless DC motor with precision PWM (Pulse Width Modulation) control, delivering high torque output at low vibration levels and exceptional energy efficiency. Its robust 304 stainless steel YZ45 pump head provides long-term resistance to corrosion and mechanical wear, while the IP31-rated enclosure ensures reliable performance under standard indoor laboratory conditions.

Key Features

• High-torque brushless DC motor with closed-loop speed regulation for stable flow across full 1–600 rpm range
• 4-digit LED display with intuitive rotary knob for real-time speed setting and direction reversal
• YZ45 pump head compatible with both Masterflex 73 and 82 tubing sizes—enabling scalable flow capacity from 0.7 to 13.8 L/min
• Modular dual-head configuration support: two YZ45 heads can be mechanically and electrically synchronized to double volumetric throughput
• Standard platinum-cured silicone tubing (1 m included) certified for USP Class VI, ISO 10993, and FDA-compliant applications
• Optional analog I/O interfaces (4–20 mA current loop, 0–5 V voltage signal) for integration into SCADA, DCS, or PLC-based automation systems
• No routine maintenance required: no lubrication, no gear replacement, no seal servicing—only periodic tubing inspection and replacement

Sample Compatibility & Compliance

The PX10-600 accommodates a broad spectrum of tubing chemistries, enabling compatibility with aggressive solvents, biological buffers, pharmaceutical formulations, food-grade liquids, and industrial slurries. Compatible tubing families include Masterflex Platinum-Cured Silicone (standard), Viton® fluoroelastomer, C-Flex® thermoplastic elastomers, and Saint-Gobain Tygon® and Pharmed® series—each selected for specific chemical resistance, biocompatibility, or regulatory compliance profiles. All recommended tubing options meet applicable standards including USP Class VI, ISO 10993-5 (cytotoxicity), and FDA 21 CFR §177.2600 for indirect food contact. When configured with validated tubing and operated within specified speed and pressure limits, the system supports GLP and GMP-aligned workflows requiring documented traceability and reproducibility.

Software & Data Management

While the PX10-600 operates as a standalone instrument with local analog control, its optional 4–20 mA and 0–5 V interfaces enable seamless integration into centralized data acquisition platforms. When connected to compliant DAQ hardware and software (e.g., LabVIEW™, Ignition SCADA, or custom Python-based logging tools), users can record real-time speed, direction, and runtime data with timestamped audit trails. For regulated environments, external software may be configured to enforce 21 CFR Part 11-compliant electronic signatures, user access controls, and immutable data archiving—provided the host system implements appropriate validation protocols. No proprietary firmware or cloud connectivity is embedded; all control logic remains transparent and deterministic.

Applications

• Continuous feed of culture media, buffers, or harvest streams in bioreactor and tangential flow filtration (TFF) systems
• High-volume reagent dispensing in automated assay platforms and clinical analyzers
• Transfer of food-grade syrups, dairy products, or flavor concentrates in pilot-scale processing lines
• Recirculation of cleaning solutions (CIP) or sanitants in hygienic loop configurations
• Delivery of abrasive slurries (e.g., ceramic suspensions, mineral dispersions) in materials science labs
• Controlled dosing of pH adjusters or coagulants in water treatment research setups

FAQ

What tubing sizes are supported by the PX10-600?
The PX10-600 with YZ45 pump head accepts both Masterflex 73 (9.6 × 15.6 mm ID × OD) and 82 (12.7 × 19.1 mm) tubing dimensions.
Can two pump heads be operated simultaneously from one driver?
Yes—the PX10-600 driver supports mechanical and electrical synchronization of up to two YZ45 heads for parallel flow paths and doubled throughput.
Is the pump suitable for sterile applications?
When used with USP Class VI-certified platinum-cured silicone or equivalent single-use tubing, and installed in aseptic enclosures, the PX10-600 meets requirements for closed-system fluid transfer in cell therapy and vaccine manufacturing workflows.
Does the unit comply with electromagnetic compatibility (EMC) directives?
The PX10-600 conforms to IEC 61326-1 (industrial EMC) and carries CE marking for use in EU laboratories; full test reports are available upon request.
What is the expected service life of the tubing at maximum speed?
Typical platinum-cured silicone tubing lifespan at 600 rpm ranges from 100–300 hours depending on fluid chemistry, temperature, and compression settings—validated per ASTM D412 tensile testing after extended duty cycles.