ISMATEC REGLO ICC Series Independent-Channel Peristaltic Pump Model 78001-60
| Brand | Cole-Parmer |
|---|---|
| Origin | USA |
| Model | 78001-60 |
| Flow Rate Range | 0.001–35 mL/min per channel |
| Speed Range | 1–100 rpm |
| Pressure Rating | 14.5 psi (1.0 bar) |
| Channels | 2 |
| Roller Configuration | 8-roller, 3-roller head per channel |
| Power Supply | 100–240 VAC, 50/60 Hz |
| Control Interface | USB, front-panel keypad |
| Flow Direction | Bidirectional per channel |
| Accuracy | ±1% of setpoint |
Overview
The ISMATEC REGLO ICC Series Independent-Channel Peristaltic Pump Model 78001-60 is an engineered solution for precise, flexible fluid handling in analytical laboratories, bioprocessing development, and continuous-flow chemistry applications. Based on the fundamental principle of peristaltic displacement—where rollers compress a flexible tubing segment to generate positive displacement—the 78001-60 delivers high reproducibility and contamination-free operation without requiring valves or seals in contact with the fluid path. Designed for multi-stream protocols, this dual-channel pump enables fully independent control of flow rate (0.001–35 mL/min) and direction (forward/reverse) on each channel, eliminating cross-talk and enabling asynchronous operation. Its compact benchtop footprint integrates seamlessly into automated workstations, HPLC auxiliary systems, cell culture perfusion setups, and reagent dispensing modules where spatial constraints and operational autonomy are critical.
Key Features
- True independent-channel control: Each of the two channels operates with dedicated speed, direction, and start/stop commands—no shared motor or controller logic.
- Bidirectional flow capability per channel: Supports recirculation, backflushing, and reversible dosing without manual tubing reconfiguration.
- High-precision 8-roller peristaltic head with three-roller compression geometry: Optimized for consistent occlusion and reduced pulsation across the full 1–100 rpm range.
- USB 2.0 interface compliant with standard CDC ACM class drivers: Enables plug-and-play integration with Windows, Linux, and macOS hosts; supports SCPI-like command syntax for script-driven automation.
- Front-panel keypad with real-time LCD display: Allows standalone operation with intuitive parameter entry, channel selection, and status monitoring—including elapsed run time and current RPM.
- Pump tube cassette system: Pre-assembled, factory-calibrated tubing sets (e.g., PharMed BPT, Tygon LFL, or Viton-compatible options) reduce setup time and minimize human error during replacement.
- ±1% flow accuracy (at steady-state, calibrated with specified tubing): Achieved through factory-trimmed motor encoder feedback and channel-specific flow correction algorithms.
Sample Compatibility & Compliance
The 78001-60 maintains compatibility with a broad spectrum of chemically resistant tubing materials, including silicone, fluoropolymer-lined elastomers, and pharmaceutical-grade thermoplastics—enabling safe handling of aqueous buffers, organic solvents, cell suspensions, and mildly abrasive slurries. As a Class I, Division 2 electrical device per UL/CSA 61010-1, it meets international safety requirements for laboratory instrumentation. While not intrinsically rated for hazardous locations, its design conforms to ISO/IEC 17025-relevant traceability practices for calibration documentation. The pump supports GLP-compliant workflows when used with audit-trail-capable host software (e.g., LabVIEW or custom Python-based controllers), and its deterministic flow behavior aligns with USP guidance for analytical instrument qualification.
Software & Data Management
The pump communicates via ASCII-based serial protocol over USB virtual COM port, supporting both manual command-line interaction and programmatic control using Python (pySerial), MATLAB Instrument Control Toolbox, or LabVIEW VISA drivers. Built-in non-volatile memory retains user-defined channel presets (up to 10 per channel), including ramp profiles, dwell times, and directional sequences. Data logging is performed externally by the host system; no internal storage is provided—ensuring data sovereignty and simplifying 21 CFR Part 11 validation pathways. Firmware updates are delivered via Cole-Parmer’s official support portal and require signed binary verification before installation.
Applications
- Multi-solvent gradient delivery in preparative chromatography systems.
- Simultaneous feeding of nutrient and waste streams in perfusion bioreactors (e.g., CHO or HEK293 cultures).
- Automated calibration standard delivery for ICP-MS and AA spectrometers.
- Controlled reagent addition in flow synthesis reactors with real-time stoichiometric balancing.
- Parallel sample dilution and spiking in environmental water analysis labs adhering to EPA Method 200.8.
- Microfluidic interface priming and buffer exchange in organ-on-chip platforms.
FAQ
Can the 78001-60 be integrated into a PLC-controlled environment?
Yes—via RS-232 (optional adapter) or USB-to-Modbus RTU gateways, enabling direct linkage to Allen-Bradley, Siemens, or Beckhoff PLCs using standard register mapping.
Is tubing calibration required for each new lot?
While factory calibration covers nominal tubing dimensions, lot-specific recalibration is recommended when switching to tubing from a different manufacturer or material grade to maintain ±1% accuracy.
Does the pump support timed dispensing with volume-based termination?
Yes—host software can calculate dispense duration from flow rate and target volume; the pump accepts TTL-level external trigger signals for synchronized start/stop events.
What maintenance intervals are specified for the 8-roller head assembly?
Cole-Parmer recommends visual inspection every 500 operating hours and roller bearing replacement every 5,000 hours under continuous 24/7 operation at ≤60 rpm.
Is firmware version history publicly documented?
Yes—release notes, known issues, and backward compatibility matrices are published in the product support section of Cole-Parmer’s global technical library.

