Masterflex L/S Programmable Peristaltic Pump with IP66 Washdown Rating

Overview

The Masterflex L/S Programmable Peristaltic Pump (Model 77975-20) is an industrial-grade, microprocessor-controlled peristaltic pumping system engineered for precision fluid handling in regulated laboratory, bioprocessing, and pilot-scale manufacturing environments. Based on the well-established roller-compression principle of peristaltic motion, this pump delivers pulse-free, non-invasive flow by sequentially compressing elastomeric tubing against a rigid track—ensuring complete fluid isolation from the drive mechanism. Its IP66-rated enclosure (equivalent to NEMA 4X) enables direct washdown with water or disinfectants, making it suitable for applications requiring frequent sanitation, such as clean-in-place (CIP) protocols, pharmaceutical buffer preparation, and food-grade transfer. The unit integrates a brushless, maintenance-free DC motor with high-torque output and thermal overload protection, supporting continuous operation across its full speed range (0.1–600 rpm) with exceptional speed stability (±0.1% accuracy). Designed for long-term reliability in demanding settings, the 316 stainless steel chassis resists corrosion from aggressive solvents, acids, and cleaning agents.

Key Features

• IP66/NEMA 4X-rated housing with fully sealed membrane keypad—enables safe, routine washdown using water, alcohol, or sodium hypochlorite solutions without risk of ingress.
• High-resolution LED display showing real-time parameters: flow rate (mL/min), rotational speed (rpm), dispensed volume (mL/L/gal), cumulative total volume, repeat count, and interval timing (up to 99 h 59 min 59 s).
• Bi-directional operation with programmable pre- and post-run tubing purge cycles—supports automated line flushing and minimizes cross-contamination between batches.
• Non-volatile memory stores calibration coefficients for up to one tubing size; retains settings after power loss.
• Programmable dispensing mode: set target volume (1–99999 units), repeat count (1–99999), and inter-dispense delay with second-level resolution.
• Analog control interface (0–20 mA / 4–20 mA / 0–10 V) enables seamless integration into PLC-based process control systems or SCADA architectures.
• Modular head compatibility: supports Easy-Load II pump head (included) for rapid tube changes and optional high-pressure, multi-channel, PTFE-lined, or sterile-configured heads.

Sample Compatibility & Compliance

The 77975-20 system accommodates a wide range of certified tubing materials—including Tygon® LFL (06429-24), Platinum-Cured Silicone (e.g., PharmaPure®, C-Flex® ULTRA), Viton®, Pharmed®, and Norprene®—each selected for specific chemical resistance, USP Class VI compliance, or extractables/leachables profiles. Tubing sizes supported span inner diameters from 0.8 mm to 9.6 mm (e.g., #13 through #36), enabling flow rates from 0.01 mL/min (microfluidic dosing) to 3400 mL/min (high-throughput transfer). All configurations meet ISO 9001:2000 quality management requirements and carry ETL and CE marks for electrical safety. When configured with validated tubing and operated under documented SOPs, the system supports GLP and GMP workflows—including FDA 21 CFR Part 11-compliant data integrity when paired with Masterflex’s optional software suite.

Software & Data Management

While the standalone 77975-20 operates via front-panel controls, it is compatible with Masterflex’s optional PC-based control software (Masterflex Connect™), which provides remote configuration, real-time monitoring, audit-trail logging, and exportable CSV reports. The software supports user-level access control, electronic signatures, and time-stamped event history—including parameter changes, start/stop events, and fault conditions—facilitating compliance with ALCOA+ data integrity principles. Analog I/O signals can be logged externally via DAQ systems for traceable process records in regulated environments.

Applications

• Pharmaceutical: Buffer/media preparation, cell culture feed, sterile filtration priming, and chromatography mobile phase delivery.
• Biotechnology: Harvest and clarification transfers, tangential flow filtration (TFF) feed, and perfusion bioreactor media exchange.
• Food & Beverage: Sanitary ingredient dosing, CIP solution circulation, and flavor concentrate blending.
• Environmental Testing: Automated sample aspiration for ICP-MS or HPLC analysis, reagent addition in automated titrators.
• Chemical Synthesis: Controlled addition of moisture-sensitive or pyrophoric reagents under inert atmosphere.
• Academic Research: Reproducible fluid handling in microreactors, organ-on-chip platforms, and custom assay automation.

FAQ

Can this pump be used in sterile or aseptic processes?
Yes—when paired with gamma-irradiated, USP Class VI-certified tubing (e.g., PharmaPure® or C-Flex® ULTRA) and installed in a laminar flow hood or isolator, the system supports aseptic fluid transfer. Optional PTFE-lined or stainless-steel pump heads further enhance compatibility.
Is tubing calibration required for each size change?
Yes—accurate volumetric dispensing requires calibration for each tubing ID and wall thickness. The drive stores one calibration profile in non-volatile memory; additional profiles may be managed externally via software.
What is the maximum backpressure the system can handle?
With the included Easy-Load II head and #36 tubing, the system sustains up to 10.2 bar (148 psi) outlet pressure—sufficient for most inline filters, packed columns, and long transfer lines.
Does the pump support regulatory-compliant audit trails?
When used with Masterflex Connect™ software and configured with password-protected user roles, electronic signatures, and immutable log files, it meets core requirements of 21 CFR Part 11 and EU Annex 11 for electronic records.
Can two pump heads be operated simultaneously from one drive?
Yes—the L/S drive supports daisy-chaining of up to two identical pump heads, enabling parallel flow paths or Y-branch splitting while maintaining synchronized speed and timing control.