Masterflex L/S Programmable Peristaltic Pump Model 07575-10

Overview

The Masterflex^® L/S Programmable Peristaltic Pump Model 07575-10 is an industrial-grade, microprocessor-controlled fluid transfer system engineered for precision, repeatability, and operational flexibility in regulated laboratory and pilot-scale process environments. Operating on the fundamental principle of peristalsis—where rollers compress elastomeric tubing against a curved housing to generate positive displacement—the pump delivers pulse-free, contamination-free fluid handling without valves, seals, or wetted metal components. This design ensures complete fluid isolation, making it ideal for sterile, corrosive, viscous, shear-sensitive, or particulate-laden media. The L/S platform integrates a brushless DC motor with closed-loop speed control, enabling stable rotational speeds across its full 0.1–600 rpm range and delivering flow rates from 0.001 mL/min up to 3400 mL/min—dependent on tubing selection and pressure conditions. Its modular architecture supports single- or multi-channel configurations, facilitating parallel processing, reagent blending, or sequential dispensing in applications ranging from analytical sample preparation to bioprocess fluid routing.

Key Features

• High-accuracy programmable dispensing: Set target volume (0.001–9999 mL), inter-dispense interval (up to 99 h 59 min 59 s), and cycle count (1–9999) via intuitive front-panel interface with seven-language support—including English, Chinese, Spanish, French, German, Italian, and Japanese.
• Speed stability and resolution: ±0.1% speed accuracy across the operating range; achieves ±0.01 rpm resolution at low speeds (e.g., 100 rpm) and ±0.1 rpm at maximum speed (600 rpm), critical for low-flow gravimetric calibration and micro-volume delivery.
• Bidirectional operation: Enables forward/reverse pumping for tube priming, backflushing, and residual liquid recovery—supporting GMP-compliant cleaning-in-place (CIP) protocols.
• Keypad lock function: Prevents inadvertent parameter changes during unattended operation or shared-lab use.
• Analog and digital I/O: Accepts 0–20 mA, 4–20 mA, and 0–10 V control signals for integration into PLC-based automation systems; supports remote start/stop and direction reversal via external logic or SCADA interfaces.
• Robust mechanical design: IP33-rated enclosure provides protection against vertically falling water droplets and solid objects >2.5 mm; constructed for continuous-duty operation under ambient lab conditions (10–40 °C, <80% RH non-condensing).
• Comprehensive pump head ecosystem: Compatible with over 20 interchangeable pump heads—including Easy-Load® 3 (for rapid tubing changeover), high-pressure variants (rated to 10.2 bar), PTFE-lined models for aggressive solvents, and multi-channel options (2-, 4-, 6-, 8-, 12-, 24-, 28-, and 32-channel) for parallelized workflows.

Sample Compatibility & Compliance

The Model 07575-10 accommodates a broad spectrum of tubing materials certified for pharmaceutical, food, and chemical applications—including platinum-cured silicone (e.g., Saint-Gobain Tygon® 3350, SPX50), fluoropolymer-reinforced elastomers (PharMed® BPT, Chem-Durance®), and FDA-compliant PVC and polyolefin compounds. Tubing inner diameters span 0.02 mm to 9.6 mm, enabling optimization for viscosity, pressure, and flow precision requirements. All configurations comply with ISO 9001:2000 quality management standards and carry ETL and CE marks for electrical safety. While not intrinsically rated for hazardous locations, optional PTFE-sealed pump heads and chemically inert tubing meet ASTM D2000 and USP Class VI requirements for extractables and leachables in drug product manufacturing. The system supports audit-ready documentation when paired with validated software platforms compliant with FDA 21 CFR Part 11 and EU Annex 11 guidelines.

Software & Data Management

Although the Model 07575-10 operates as a standalone instrument with embedded firmware, it is fully compatible with Masterflex’s optional PC-based control suite (Masterflex Connect™), which enables centralized configuration, real-time monitoring, and export of time-stamped operation logs (start/stop timestamps, total volume dispensed, error codes). When integrated with LIMS or MES platforms via Modbus RTU or analog signal mapping, the pump contributes traceable data to electronic batch records. Built-in memory retains one user-defined calibration profile per tubing size—allowing volumetric correction based on fluid density and tubing elasticity—essential for meeting USP <1058> analytical instrument qualification (AIQ) criteria. Keypad lock status, direction state, and current RPM are logged internally for GLP/GMP audit trails.

Applications

• Automated liquid handling in QC/QA labs: Precise filling of vials, syringes, and microtiter plates for dissolution testing, content uniformity assays, and standard solution preparation.
• Bioprocessing: Feed and harvest control in perfusion bioreactors; buffer and media transfer in downstream purification skids.
• Environmental testing: Continuous sampling of wastewater streams, groundwater monitoring, and automated reagent addition in titration systems.
• Chemical synthesis: Controlled addition of moisture-sensitive or pyrophoric reagents; metered dosing in flow chemistry reactors.
• Food & beverage R&D: Flavor concentrate blending, pH-adjustment acid/base dosing, and sterile fill simulation studies.
• Academic research: Teaching fluid mechanics principles, calibrating flow sensors, and developing microfluidic interface modules.

FAQ

What tubing sizes and materials are supported?
The pump accepts tubing with inner diameters from 0.02 mm to 9.6 mm, including Tygon® LFL, C-Flex®, PharMed®, Viton®, Norprene®, and platinum-cured silicones—each selected for compatibility with specific chemical, temperature, and regulatory requirements.
Can this pump be integrated into a GMP-compliant manufacturing environment?
Yes—when used with validated tubing, calibrated flow profiles, and connected to audit-trail-capable software (e.g., Masterflex Connect™ with 21 CFR Part 11 mode enabled), the system supports IQ/OQ/PQ protocols and meets ALCOA+ data integrity principles.
Is bidirectional operation suitable for cleaning protocols?
Absolutely—reversing flow aids in clearing residual fluid from tubing and prevents cross-contamination between batches, aligning with FDA guidance on equipment cleaning validation.
How is flow accuracy maintained across varying viscosities?
Users perform volumetric calibration using known-density fluids and store correction factors per tubing size; the pump applies these offsets automatically during programmed dispensing.
Does the pump support multi-channel synchronization?
When equipped with multi-head controllers (e.g., Model 07523-90 base unit), up to 32 channels can operate in synchronized or independent modes—enabling complex fluid routing strategies without external timing hardware.