BXM-75M Benchtop High-Pressure Steam Sterilizer

Overview

The BXM-75M Benchtop High-Pressure Steam Sterilizer is an ISO-compliant, microprocessor-controlled autoclave engineered for reliable terminal sterilization of heat-stable laboratory materials using saturated steam under pressure. It operates on the validated principle of moist-heat sterilization—leveraging steam penetration at elevated temperature and pressure to irreversibly denature microbial proteins and nucleic acids. Designed for routine use in academic laboratories, quality control facilities, and small-scale bioprocessing units, the system delivers consistent lethality (F₀ ≥ 12 min) across heterogeneous loads including culture media, glassware, stainless-steel instruments, textiles, and sealed containers (e.g., serum bottles, vials). Its integrated pre-vacuum cycle ensures complete air removal prior to steam admission—critical for achieving uniform thermal distribution in dense or porous loads where cold-air pockets would otherwise impede sterilization efficacy per ISO 17665-1 and EN 285 standards.

Key Features

• Pre-vacuum air removal cycle (adjustable frequency: 2–99 cycles) to maximize steam penetration into complex or densely packed loads
• Pulsed vacuum drying function with residual moisture <1%, eliminating post-sterilization transfer and secondary contamination risk
• BRIGHT II touchscreen HMI with intuitive icon-based navigation, real-time graphical process display, and multilingual interface support
• 16 programmable user-defined cycles—each storing temperature, pressure, time, F₀, and phase sequence—for repeatable, SOP-driven operation
• Integrated sample temperature probe (standard) enabling direct monitoring of load core temperature—supporting validation and process verification per USP & ISO 11134
• Double automatic water replenishment system with dual inlet options (tap or purified water), coupled with low-water auto-shutdown and alarm
• SUS304 stainless-steel chamber and baskets with mirror-finish interior for corrosion resistance and ease of cleaning; no internal heating elements—maximizing usable volume and thermal efficiency
• Passive cooling via integrated condenser + axial fan assembly, reducing post-cycle wait time by up to 40% compared to passive cooldown
• HEPA-filtered air intake during vacuum break and drying phases to prevent recontamination from ambient air
• Comprehensive safety architecture: dual mechanical/electronic door interlock, overpressure self-locking, overtemperature cutoff, dry-run protection, and fault self-diagnosis with error code logging

Sample Compatibility & Compliance

The BXM-75M accommodates a broad range of sterilizable items: liquid media (in bottles or flasks), surgical instruments, pipette tips, Petri dishes, gowns, and wrapped textile packs. Its pre-vacuum capability supports sterilization of sealed containers (e.g., crimp-top vials, screw-cap bottles) without compromising sterility assurance. The chamber’s 75 L capacity and Ø400 mm × 700 mm geometry allow vertical stacking of standard instrument trays or stacked media bottles. All sterilization cycles comply with ISO 17665-1:2017 (Moist heat sterilization of health care products), EN 285:2015 (Large steam sterilizers), and align with FDA 21 CFR Part 11 requirements when paired with optional thermal printer and audit-trail-enabled data export. Built-in data logging meets GLP/GMP documentation expectations for traceability.

Software & Data Management

Sterilization parameters—including time, temperature, pressure, F₀, vacuum cycles, and real-time load temperature—are continuously recorded and stored internally (≥1000 cycles). Data export is performed via USB flash drive in read-only, tamper-evident .CSV format—ensuring integrity for regulatory review. Optional thermal printer (SPR-type, domestic model) provides hardcopy output of full cycle curves, timestamps, and critical parameters—fully compliant with ALCOA+ principles. The system supports periodic firmware updates via USB and maintains full event logs with timestamps for maintenance history, alarm events, and operator actions.

Applications

• Routine sterilization of microbiological growth media (agar, broth) in glass or plastic containers
• Decontamination of biohazardous waste (BSL-1/2) with HEPA-filtered exhaust and negative-pressure compensation
• Preparation of sterile surgical kits, labware, and reusable PPE in research and clinical labs
• Validation support for sterilization process development—enabled by precise temperature mapping and F₀ calculation
• Media melting and holding (40–100 °C) with programmable ramp/soak profiles
• Post-sterilization drying of metal instruments, glassware, and woven fabrics without condensation residue

FAQ

What is the maximum operating temperature and pressure?

The BXM-75M achieves a maximum sterilization temperature of 135 °C at an operating pressure of 0.22 MPa (gauge), with a safety-rated design pressure of 0.25 MPa.

Does the unit support validation and compliance documentation?

Yes—integrated temperature probe, F₀ calculation, USB data export in immutable format, and optional thermal printer enable full compliance with ISO 17665, EN 285, and FDA 21 CFR Part 11 audit requirements.

Can it sterilize sealed vials or bottles?

Yes—the pre-vacuum cycle ensures thorough air evacuation, allowing saturated steam to penetrate sealed containers such as serum bottles and crimped vials without compromising sterility assurance.

Is the chamber fully drainable and cleanable?

The chamber features a seamless SUS304 interior with mirror-polished finish and zero internal heaters—facilitating rapid wipe-down, chemical disinfection, and validation-compatible cleaning protocols.

What safety certifications does it meet?

The unit conforms to IEC 61010-1 (Safety Requirements for Electrical Equipment) and incorporates redundant mechanical and electronic interlocks, overpressure relief, and real-time thermal monitoring per national electrical safety standards.