BRAND Titrette® 4760251 Digital Burette Dispenser
| Brand | BRAND® |
|---|---|
| Origin | Germany |
| Model | 4760251 |
| Capacity | 25 mL |
| Accuracy (A) | ≤ ±0.07% / ≤ ±18 µL |
| Coefficient of Variation (CV) | ≤ 0.025% / ≤ 6 µL |
| Compliance | DIN EN ISO 385 |
| Interface | RS232 (optional) |
| Power | Battery-operated (no external power required) |
Overview
The BRAND Titrette® 4760251 Digital Burette Dispenser is a precision-engineered, portable electronic burette designed for quantitative liquid dispensing in analytical, quality control, and routine laboratory applications. Unlike traditional glass burettes or motor-driven titrators, the Titrette® operates on a mechanical–electronic hybrid principle: it uses a high-precision glass syringe barrel combined with an integrated optical encoder system to detect plunger displacement in real time. This enables true volumetric measurement—not inferred from time or pump speed—but directly traced to calibrated glass volume graduation per ISO 385. Its self-contained, battery-powered architecture eliminates dependency on AC power, making it suitable for field use, cleanrooms, gloveboxes, or confined benchtop environments where electrical outlets are unavailable or restricted. The device delivers traceable, repeatable dispense volumes across its full 25 mL range, with metrological performance validated against DIN EN ISO 385 Class A tolerances—ensuring equivalence to certified Class A glass burettes in both accuracy and reproducibility.
Key Features
- Optical displacement sensing with dual-axis encoder for real-time volume tracking and direction detection (dispense vs. refill)
- Manual rotary control knob enabling tactile, stepless adjustment—from single-drop precision to rapid bulk dispensing—without mode-switching buttons
- High-contrast LCD display showing volume to three decimal places (e.g., 12.345 mL) when dispensing ≤20 mL; auto-scaling resolution maintains readability across the full range
- Integrated Easy Calibration function supporting single-point or multi-point verification using certified weights or gravimetric standards
- Programmable auto-shutdown after 10 minutes of inactivity to extend battery life; low-battery indicator alerts prior to operational interruption
- Modular design with tool-free disassembly: glass barrel, PTFE-coated piston, and sealing components are accessible for cleaning, sterilization (autoclavable up to 121°C), or replacement
- RS232 serial interface (optional accessory) compliant with standard laboratory data acquisition protocols for direct export to LIMS or spreadsheet software
Sample Compatibility & Compliance
The Titrette® 4760251 is compatible with aqueous solutions, organic solvents (including ethanol, acetone, and chloroform), dilute acids and bases, and viscous liquids up to 500 mPa·s (e.g., glycerol/water mixtures). Its chemically resistant materials—including borosilicate glass (Duran®), FEP/PTFE seals, and stainless-steel drive mechanism—ensure long-term stability and minimal adsorption or leaching. All volumetric performance specifications conform to DIN EN ISO 385:2021 (Class A), and the device supports GLP/GMP documentation workflows through optional audit-trail-capable software interfaces. While not intrinsically rated for hazardous area use, its spark-free mechanical operation makes it suitable for solvent-rich fume hood environments.
Software & Data Management
When equipped with the RS232 interface and optional Titrette® Control Software (v3.2+), the 4760251 supports bidirectional communication: users can predefine dispensing sequences, store calibration logs with timestamps and operator IDs, and export raw volume data in CSV format. The software enforces user-level access control (administrator/operator modes) and records all parameter changes, fulfilling basic requirements for 21 CFR Part 11 compliance when deployed with appropriate IT infrastructure (e.g., electronic signatures, audit trails, and secure storage). No cloud connectivity or proprietary firmware updates are required—firmware remains static unless explicitly upgraded via certified service centers.
Applications
- Standardized acid–base titrations in food & beverage QA (e.g., titratable acidity in dairy per ISO 8586, SH units)
- Redox and complexometric titrations in environmental testing (e.g., COD, hardness, chloride determination per APHA/ISO methods)
- In-process control during pharmaceutical manufacturing (e.g., residual solvent quantification, excipient blending verification)
- Calibration of pipettes and automated liquid handlers using gravimetric validation protocols (ISO 8655-6)
- Field-based water quality assessment where portability, battery operation, and ISO-compliant accuracy are critical
FAQ
Does the Titrette® 4760251 require external power or charging?
No—it operates exclusively on two AA alkaline batteries (included), providing >10,000 full-range dispenses per set. Rechargeable NiMH batteries are not recommended due to voltage drift affecting encoder accuracy.
Can the device be calibrated in-house without specialized equipment?
Yes—using the built-in Easy Calibration routine and certified reference weights (e.g., ASTM E542 Class M1), users can perform full-range verification at any time without sending the unit to a service lab.
Is the 25 mL glass barrel interchangeable with other Titrette® models?
No—the 4760251 uses a proprietary 25 mL barrel with integrated optical scale and encoder coupling; barrels are not cross-compatible across capacity variants (e.g., 10 mL or 50 mL models).
What maintenance intervals are recommended for routine use?
Daily visual inspection of seals and piston smoothness; monthly cleaning with isopropanol and distilled water; annual verification of accuracy if used ≥20 times per day in regulated environments.
Does the RS232 interface support modern USB-to-serial adapters?
Yes—standard FTDI- or CH340-based USB-RS232 adapters are fully compatible; no drivers beyond OS-native CDC ACM support are required on Windows/macOS/Linux.
