ANYAN AYAN-F80 Laboratory Short-Path Molecular Distillation System
| Brand | ANYAN (Hangzhou Anyan Instrument Co., Ltd.) |
|---|---|
| Origin | Zhejiang, China |
| Manufacturer Type | Authorized Distributor |
| Country of Manufacture | China |
| Model | AYAN-F80 |
| Feed Rate | 0.5–4.0 L/h |
| Effective Evaporation Area | 0.1 m² |
| Evaporator Inner Diameter | 80 mm |
| Condensation Area | 0.15 m² |
| Compatible Collection Flasks | Standard KL/ISO-K glassware (e.g., 50–500 mL round-bottom flasks) |
Overview
The ANYAN AYAN-F80 Laboratory Short-Path Molecular Distillation System is an engineered vacuum-based liquid–liquid separation platform designed for high-value thermal-sensitive compounds. Operating under high vacuum (typically <0.1 Pa), it exploits the difference in molecular mean free path between light and heavy components—enabling separation at temperatures significantly below their atmospheric boiling points. Unlike conventional fractional or steam distillation, short-path molecular distillation minimizes thermal exposure by maintaining a very short distance (<50 mm) between the evaporating surface and the condenser, thereby reducing residence time and preventing decomposition of labile substances such as vitamins, polyunsaturated fatty acids (PUFAs), natural antioxidants (e.g., tocopherols), and pharmaceutical intermediates. The system integrates a precisely temperature-controlled heating mantle, a vertically oriented rotating wiper-film evaporator with an 80 mm internal diameter, a water-cooled condenser with 0.15 m² active surface area, and modular collection ports compatible with standard ground-glass jointed flasks.
Key Features
- Rotating wiper-film evaporator with PTFE-coated blades ensures uniform thin-film formation and consistent heat transfer across the 0.1 m² evaporation surface
- Digital PID temperature control (±0.5 °C accuracy) for both evaporator and condenser zones, independently adjustable from ambient to 250 °C
- Integrated high-vacuum system compatibility: supports ultimate pressures down to 0.01 Pa when paired with a dual-stage oil-sealed or dry scroll vacuum pump (pump not included)
- Modular design allows rapid assembly/disassembly; all wetted parts constructed from borosilicate glass 3.3 and PTFE—compliant with USP Class VI and ISO 8536 standards
- Feed rate regulation via precision peristaltic pump (0.5–4.0 L/h range), enabling reproducible thin-film thickness and stable operation across varying viscosities
- Condenser geometry optimized for high condensation efficiency: vertical orientation with double-jacket cooling channel and integrated coolant flow monitoring
Sample Compatibility & Compliance
The AYAN-F80 accommodates a broad spectrum of thermally sensitive feedstocks—including fish oil concentrates, phospholipid extracts, CBD distillates, silicone oils, and polymer precursors—without catalytic degradation. Its all-glass fluid path eliminates metal ion leaching, making it suitable for GLP-compliant purification workflows in analytical reference material preparation. While the instrument itself does not carry CE or UL certification, its mechanical and electrical architecture conforms to IEC 61010-1 safety requirements for laboratory equipment. When operated within validated parameters (vacuum level, feed rate, temperature gradient), the system supports documentation practices aligned with FDA 21 CFR Part 11 expectations for electronic records—particularly when interfaced with compliant data acquisition software.
Software & Data Management
The AYAN-F80 operates via front-panel digital interface with real-time display of evaporator temperature, condenser temperature, vacuum pressure (via optional Pirani/capacitance gauge), and feed rate. Optional RS-485 or USB-to-serial connectivity enables integration with third-party SCADA or LIMS platforms for automated logging of critical process parameters. All operational setpoints and runtime events are timestamped and stored locally on non-volatile memory (retention ≥10 years). Audit trails can be exported in CSV format for QA review, supporting traceability requirements in regulated environments where batch consistency and deviation reporting are mandatory.
Applications
- Purification of omega-3 ethyl esters (EPA/DHA) from crude fish oil hydrolysates
- Deacidification and deodorization of vegetable oil distillates (e.g., rice bran oil, sunflower oil)
- Isolation of monoglycerides and diglycerides for food emulsifier synthesis
- Recovery and concentration of natural terpenes and sesquiterpenes from essential oil fractions
- Removal of residual solvents (e.g., hexane, ethanol) from botanical extracts prior to formulation
- Preparative-scale fractionation of synthetic polymers and oligomers for GPC calibration standards
FAQ
What vacuum level is required for optimal performance?
Optimal separation occurs at ≤0.1 Pa; system performance should be verified using a calibrated vacuum gauge prior to each run.
Can the AYAN-F80 handle highly viscous feedstocks (e.g., >500 cP)?
Yes—rotating wiper design maintains film integrity up to 1,200 cP at 80 °C; pre-heating feed to reduce viscosity is recommended.
Is the condenser cooled by circulating water only, or is cryogenic cooling supported?
Standard configuration uses tap or chiller-circulated water (5–25 °C); dry ice/acetone jacketing is mechanically feasible but requires custom adapter.
How is endpoint detection managed during continuous operation?
No built-in endpoint sensor; users rely on real-time vacuum stability, distillate flow rate, and refractive index monitoring via external inline probe.
Are spare parts and consumables (e.g., wiper blades, O-rings) available through ANYAN’s global distribution network?
Yes—PTFE wiper assemblies, Kalrez® sealing kits, and standardized glass components (DIN 29, ISO-K 29/32) are stocked and ship within 5 business days ex-Zhejiang warehouse.
