SOCOREX Acura 835 Adjustable Volume Single-Channel Pipette
| Brand | SOCOREX |
|---|---|
| Origin | Switzerland |
| Model | 835 |
| Pipette Type | Manual Single-Channel |
| Volume Range | 0.2–10 mL |
| Maximum Capacity | 10 mL |
| Accuracy | ±0.5% at maximum volume |
| Sterilization | Full-unit autoclavable at 121 °C |
| Compliance | CE-marked, conforms to IVD Directive 98/79/EC |
| Weight | ~120 g (varies by volume setting) |
| Tip Compatibility | Universal conical tips (including filtered and low-retention), Pasteur pipette adapters for 2 mL and 5 mL glass capillaries |
Overview
The SOCOREX Acura 835 is a high-precision, manually operated single-channel adjustable-volume pipette engineered for reproducible liquid handling across broad volumetric ranges—from 0.2 mL to 10 mL. Designed and manufactured in Switzerland, it employs an air-displacement principle with a precisely calibrated piston mechanism, ensuring traceable performance aligned with ISO 8655:2022 (Pipettes — Calibration and Performance Testing). Its robust stainless-steel and high-grade polymer architecture supports rigorous laboratory workflows, including GLP-compliant sample preparation, clinical diagnostics, biopharmaceutical QC, and academic research requiring volumetric integrity at the milliliter scale. Unlike fixed-volume or electronic alternatives, the Acura 835 delivers full manual control without dependency on batteries or software—ideal for environments where simplicity, reliability, and regulatory transparency are paramount.
Key Features
- Human-Centered Ergonomics: Weighing approximately 120 g at mid-range settings, the Acura 835 features a balanced center-of-gravity design and low plunger activation force (≤1.8 N at 10 mL), reducing operator fatigue during repetitive dispensing tasks.
- JUSTIP™ Tip Ejector Adjustment: The height-adjustable tip ejector accommodates variations in tip cone geometry—including universal, low-binding, and filtered tips—ensuring consistent ejection force and minimizing tip retention or slippage.
- Full-Unit Autoclavability: All components—including the shaft, plunger, and tip cone—are rated for 121 °C, 20 min steam sterilization per EN 285, enabling seamless integration into sterile microbiology, cell culture, and cleanroom workflows.
- Intuitive Volume Setting & Locking Mechanism: A dual-action top dial allows rapid, tactile volume adjustment with visual feedback via a large, front-facing digital window. An integrated mechanical lock prevents accidental volume drift during operation or transport.
- User-Accessible Calibration System: The built-in calibration interface requires no tools: users can adjust internal piston displacement directly via a removable calibration rod, facilitating in-lab verification and traceable adjustments compliant with ISO 8655 Annex C.
- Pasteur Pipette Adapters: Optional 2 mL and 5 mL glass capillary compatibility extends utility beyond standard polypropylene tips—critical for viscous, volatile, or particulate-laden samples where tip adsorption or aerosol generation must be minimized.
Sample Compatibility & Compliance
The Acura 835 handles aqueous solutions, buffers, diluted acids/bases, ethanol/water mixtures, and cell suspensions within its specified viscosity and vapor pressure limits (≤500 cP; ≤40 kPa at 20 °C). It is validated for use with certified low-retention and filter tips meeting ISO 8655-5 requirements. Regulatory compliance includes CE marking under Directive 98/79/EC (In Vitro Diagnostic Medical Devices), adherence to RoHS 2011/65/EU, and conformity with ISO 9001-certified manufacturing processes. While not inherently 21 CFR Part 11 compliant (as it lacks electronic audit trails), its mechanical calibration system supports GxP-aligned documentation when paired with lab-specific SOPs and calibration logs.
Software & Data Management
As a fully manual instrument, the Acura 835 operates independently of software or connectivity protocols. However, its calibration traceability aligns with data integrity frameworks: each adjustment is physically recorded in lab notebooks or LIMS via documented procedures referencing ISO 8655 calibration protocols. Users may integrate the pipette into electronic quality management systems (eQMS) by linking calibration events to unique serial numbers and assigning responsibility via signature-based log entries. SOCOREX provides NIST-traceable calibration certificates upon request from accredited service centers—supporting FDA audit readiness and internal QA audits.
Applications
- Preparation of standard curves and dilution series in ELISA, qPCR, and immunoassay workflows
- Transfer of culture media, reagents, and harvest supernatants in mammalian and microbial cell culture
- Volumetric dosing in pharmaceutical stability studies and excipient blending
- Calibration of spectrophotometric cuvettes and HPLC vials requiring precise 1–10 mL additions
- Field-deployable liquid handling in mobile labs or resource-limited settings where power independence is essential
FAQ
Is the Acura 835 compatible with non-SOCOREX tips?
Yes—its conical tip interface meets ISO 8655-3 dimensional specifications, ensuring interoperability with major third-party tip brands. However, optimal accuracy and leak-free operation are guaranteed only with SOCOREX-certified tips or those validated per ISO 8655-5.
What is the recommended calibration frequency?
Per ISO 8655-6 and industry best practice, calibration should occur every 6 months under routine use. High-frequency or high-risk applications (e.g., clinical diagnostics) may require quarterly verification. Always recalibrate after autoclaving, mechanical impact, or observed performance deviation.
Can the pipette be used with viscous or volatile liquids?
For liquids >20 cP, reverse pipetting technique is advised. Volatile solvents (e.g., acetone, chloroform) require pre-wetting and rapid dispensing to minimize evaporation error; use of positive-displacement tips is recommended for sustained accuracy.
How do I verify seal integrity before calibration?
Attach a new tip, aspirate distilled water to nominal volume, hold vertically for 15 seconds—if no droplet forms at the tip aperture, the seal is intact. If leakage occurs, inspect tip cone cleanliness, O-ring lubrication, and piston alignment.
Does the Acura 835 support GLP/GMP documentation?
Yes—its mechanical design enables unambiguous calibration records, serial-number traceability, and user-defined calibration logs. When combined with controlled documentation practices (e.g., dated signatures, version-controlled SOPs), it fulfills core GLP requirements for equipment qualification and performance monitoring.
