OMNI International GLH 850 Digital Benchtop Homogenizer
| Brand | OMNI International |
|---|---|
| Origin | USA |
| Model | GLH 850 |
| Instrument Type | Probe-type Rotor-Stator Homogenizer |
| Dimensions (W×D×H) | 69.9 × 69.9 × 216 mm |
| Sample Volume Range | 0.2–5000 mL |
| Motor Power | 850 W |
| Speed Range | 5000–25,000 rpm |
| Compatible Probe Diameters | 5, 7, 10, 20, 30 mm (stainless steel) |
Overview
The OMNI International GLH 850 Digital Benchtop Homogenizer is an engineered solution for high-efficiency mechanical homogenization in life science, pharmaceutical, clinical, and industrial laboratories. Utilizing the proven rotor-stator principle—where a rapidly rotating probe generates intense shear, cavitation, and turbulent flow within the sample—the GLH 850 delivers consistent particle size reduction, cell lysis, emulsification, and dispersion across diverse matrices. Its 850 W brushless motor ensures stable torque delivery across the full speed range (5,000–25,000 rpm), enabling reproducible processing of viscous, fibrous, or particulate-laden samples—including mammalian tissues, plant material, microbial cultures, and suspension-based formulations. Designed for benchtop integration, the compact footprint (69.9 × 69.9 × 216 mm) supports modular lab layouts while maintaining ergonomic accessibility and operational safety.
Key Features
- Digital speed control with real-time RPM display and ±50 rpm accuracy, ensuring method reproducibility between operators and shifts.
- Intelligent thermal management system prevents motor overheating during extended operation, supporting uninterrupted processing of sequential samples.
- Quick-release probe coupling mechanism allows tool-free, single-hand attachment and removal of stainless-steel or Omni Tip probes—minimizing downtime during multi-sample workflows.
- Three-stage safety interlock: (1) lid-sensor activation, (2) probe-insertion detection, and (3) over-speed/over-temperature shutdown—compliant with IEC 61010-1 for laboratory equipment safety.
- Non-slip rubberized base and low-noise acoustic housing (<65 dB at 1 m) reduce vibration transmission and ambient noise, suitable for shared or ISO Class 7 cleanroom-adjacent environments.
Sample Compatibility & Compliance
The GLH 850 accommodates sample volumes from 0.2 mL to 5,000 mL using a comprehensive probe library. Stainless-steel probes (5–30 mm diameter) are validated for high-intensity applications involving tough biological tissues, frozen samples, or abrasive suspensions; wide-window variants (e.g., G7-115STW) provide coarser homogenization for rapid pre-processing steps. The Omni Tip line—available in soft-tissue, hard-tissue, and high-efficiency composite configurations—offers sterility assurance via autoclaving (121°C, 20 min, 15 psi) or gamma irradiation (25 kGy), meeting ISO 11137 requirements. Each Omni Tip is individually barcoded and traceable to lot-specific biocompatibility testing per USP and . The system supports GLP-compliant documentation when paired with OMNI’s optional audit-trail-enabled software (see Software & Data Management).
Software & Data Management
While the GLH 850 operates as a standalone instrument with intuitive front-panel controls, it is fully compatible with OMNI’s Homogenizer Control Suite (v3.2+), a Windows-based application enabling method storage, parameter logging (RPM, time, probe ID, operator tag), and export to CSV or PDF for regulatory submissions. When configured with optional USB data-logging module, the system records timestamped operational events—including start/stop, speed changes, and fault codes—with tamper-evident digital signatures aligned with FDA 21 CFR Part 11 requirements for electronic records and signatures. All firmware updates are digitally signed and verified prior to installation, ensuring integrity throughout the device lifecycle.
Applications
- Pre-analytical sample preparation for downstream molecular assays (DNA/RNA extraction, protein solubilization).
- Homogenization of pharmacopeial reference standards (USP , ) and generic drug suspensions.
- Cell disruption for enzyme activity studies, organelle isolation, and vaccine antigen release.
- Emulsion stabilization trials in food science and cosmetic formulation development.
- Environmental sample processing (soil slurry homogenization, biofilm dissociation from filtration membranes).
FAQ
What probe types are recommended for sterile, single-use applications?
Omni Tip disposable probes (e.g., model 30750, 32750H) are gamma-irradiated and certified pyrogen-free, validated for use in ISO 5 laminar flow hoods and cGMP manufacturing environments.
Can the GLH 850 be integrated into automated liquid handling platforms?
Yes—via optional RS-232 or TTL-level trigger interface, enabling synchronization with robotic arms or programmable timers for unattended batch processing.
Is calibration required for routine operation?
Routine calibration is not mandated; however, annual verification of speed accuracy against NIST-traceable tachometer is recommended per ISO/IEC 17025 quality systems.
How does the GLH 850 compare to rotor-stator homogenizers with analog dials?
Digital speed regulation eliminates mechanical drift and provides ±0.5% setpoint stability over time—critical for SOP-driven labs requiring inter-laboratory comparability.
Are replacement parts and service support available globally?
OMNI International maintains authorized service centers in North America, EMEA, and APAC regions, with probe inventory stocked regionally to ensure ≤72-hour dispatch for critical spares.
