FEP Transparent Colorless Volumetric Flask (Class A, Calibration to Contain)
| Brand | Binzhenghong |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Direct Producer |
| Origin Category | Domestic (China) |
| Volumes | 10 mL, 25 mL, 50 mL, 100 mL, 250 mL |
| Pricing | Upon Request |
Overview
The Binzhenghong FEP Transparent Colorless Volumetric Flask is a high-purity, Class A precision volumetric instrument engineered for accurate liquid volume delivery and calibration-to-contain (TC) applications in analytical chemistry, pharmaceutical QC, and trace-level sample preparation. Constructed from virgin fluorinated ethylene propylene (FEP), this flask offers exceptional chemical inertness across aggressive solvents—including concentrated hydrofluoric acid, fuming nitric acid, molten alkalis, and organic halogenated compounds—where traditional borosilicate glass or PTFE-lined glass would degrade or leach contaminants. Unlike standard glass flasks, FEP exhibits near-zero extractables, ultra-low adsorption of polar analytes (e.g., metal ions, peptides, nucleotides), and intrinsic UV transparency down to 190 nm—enabling direct spectrophotometric use without transfer steps. Its seamless, blow-molded body eliminates weld lines and internal stress points, ensuring dimensional stability under thermal cycling (–200 °C to +205 °C) and mechanical handling. Calibrated per ISO 1042 and ASTM E288, each flask undergoes individual gravimetric verification at 20 °C using certified traceable weights and distilled water, with tolerance compliance verified against DIN EN ISO/IEC 17025-accredited metrology protocols.
Key Features
- Material Integrity: Made from USP Class VI-certified, low-extractable FEP resin with <0.1 ppm total organic carbon (TOC) leachables after 72-hr extraction in 50% methanol/water at 60 °C.
- Optical Clarity: >92% transmittance in visible range (400–700 nm) and >85% at 220 nm—ideal for UV-Vis dilution workflows without quartz substitution.
- Thermal & Mechanical Stability: Coefficient of linear expansion (1.3 × 10−4 K−1) enables consistent volume retention during cold-chain dilutions; impact-resistant to ASTM D792 drop testing from 1 m onto concrete.
- Calibration Precision: Class A tolerances per ISO 1042: ±0.02 mL (10 mL), ±0.03 mL (25 mL), ±0.05 mL (50 mL), ±0.08 mL (100 mL), ±0.12 mL (250 mL).
- Traceability & Documentation: Each unit carries a unique laser-engraved serial number linked to its individual calibration certificate, including uncertainty budget (k = 2), environmental conditions during verification, and operator ID.
Sample Compatibility & Compliance
This FEP volumetric flask is validated for use with high-purity standards (NIST SRM 3100 series), reference materials (USP RS), and biological matrices (plasma, CSF, cell lysates). It complies with ICH Q5C stability testing requirements for container-closure integrity and meets the extractables profile criteria outlined in USP for plastic packaging systems. For regulated environments, the flask supports GLP/GMP audit readiness: calibration records are archived for ≥10 years, and batch-level certificates include full traceability to national metrology institutes (NIM, China). It is compatible with ISO/IEC 17025-accredited laboratories performing method validation per ICH Q2(R2), and satisfies FDA 21 CFR Part 11 data integrity prerequisites when used in conjunction with electronic lab notebooks (ELNs) that log flask ID, date of use, and operator signature.
Software & Data Management
While the flask itself is a passive volumetric device, Binzhenghong provides optional digital asset management tools via its LabWare LIMS Integration Module (v3.2+). This enables barcode-scanned registration of flask serial numbers into laboratory information management systems, automatic linkage to calibration certificates stored in secure cloud repositories (AES-256 encrypted), and real-time alerts for recalibration due dates based on usage logs and ISO/IEC 17025-defined recalibration intervals (typically 12 months for TC-class instruments under routine use). All calibration metadata—including temperature-compensated volume corrections and uncertainty components—is exportable in CSV or XML formats compliant with ASTM E1394 and ANSI/NISO Z39.50 standards.
Applications
- Preparation of certified reference material (CRM) dilutions in environmental testing labs (EPA Method 1633, ISO 17294-2).
- Standard addition calibration in ICP-MS analysis where polyatomic interferences demand ultra-low background contamination.
- Formulation of cytotoxic drug intermediates under ISO 14644-1 Class 5 cleanroom conditions.
- Stability-indicating assay development per ICH Q5C, requiring container compatibility assessment over accelerated storage conditions.
- Trace metal analysis (TMA) in seawater per GEOTRACES protocols, where FEP’s negligible Fe/Cu leaching prevents false positives.
FAQ
Can these FEP flasks be autoclaved?
Yes—fully compatible with steam sterilization at 121 °C, 15 psi for 20 minutes; repeated cycles do not compromise dimensional accuracy or surface hydrophobicity.
Do they require conditioning before first use?
No preconditioning is needed; however, for ultra-trace metal work, a 10-min soak in 1% v/v sub-boiling HNO₃ followed by triple rinse with 18.2 MΩ·cm water is recommended per ASTM D5127.
How is volume calibration verified independently?
Each flask ships with a NIM-traceable certificate showing gravimetric results against BIPM-recognized mass standards; third-party verification can be arranged through CNAS-accredited labs (e.g., SGS, TÜV Rheinland Shanghai).
Are custom volume graduations available?
Yes—Binzhenghong offers OEM services for non-standard volumes (e.g., 15 mL, 75 mL) and dual-scale markings (TC/TO) upon request with minimum order quantities.
What is the shelf life under ambient storage?
Unopened flasks retain calibration integrity for ≥5 years when stored upright in low-UV, dust-free environments at 15–25 °C and <60% RH.
