German-Made Mouse Tracheal Intubation Surgical Instrument Set – Model SP1008-M
| Origin | Germany |
|---|---|
| Supplier Type | Authorized Distributor |
| Import Status | Imported |
| Model | SP1008-M |
| Pricing | Available Upon Request |
Overview
The German-made Mouse Tracheal Intubation Surgical Instrument Set (Model SP1008-M) is a purpose-engineered, CE-compliant collection of precision microsurgical tools designed exclusively for endotracheal intubation and associated airway management procedures in murine models. This set supports critical experimental workflows requiring controlled ventilation—including thoracotomy, neuromuscular blockade studies, acute ileus modeling, and inhalational anesthesia delivery via isoflurane. The instruments are optimized for anatomical scale, tissue delicacy, and procedural reproducibility in mice (typically 20–35 g), enabling reliable tracheal exposure, laryngeal visualization, cannula insertion, and secure airway stabilization. While the set provides all manual instrumentation necessary for surgical intubation—including dissection, incision, hemostasis, suture placement, and wound closure—it does not include anesthesia vaporizers, ventilators, or gas delivery systems, which must be sourced separately per institutional IACUC protocols and ISO 8573-1 compressed air quality requirements.
Key Features
- Manufactured in Germany to DIN EN ISO 13485 medical device quality standards, with traceable batch documentation and stainless steel grade 1.4404 (AISI 316L) construction for corrosion resistance and autoclave compatibility (up to 134 °C, 21 psi, 18 min).
- Micro-scale geometry calibrated for murine anatomy: fine-tipped scissors (225 mm and 212.5 mm lengths), ultra-fine toothed forceps (250 mm straight and curved), and angled dissecting forceps ensure minimal tissue trauma during tracheal dissection and laryngeal manipulation.
- Olsen-Hegar needle holders feature integrated tungsten-carbide jaw inserts and spring-assisted actuation for precise suture control with #2-O needles (0.35 mm diameter) and 2/0 polypropylene suture (0.32 mm, 22.5 m spool).
- Included wound management accessories—7 mm suture adapter, 7 mm wound clips, and dedicated suture removal tool—facilitate standardized closure techniques aligned with ARRIVE 2.0 reporting guidelines and GLP-compliant surgical recordkeeping.
- Complete co-packaged hemostatic kit (coagulation instrument set) enables rapid control of capillary bleeding without thermal damage to adjacent tracheal cartilage rings or recurrent laryngeal nerve branches.
Sample Compatibility & Compliance
This instrument set is validated for use in C57BL/6, BALB/c, and CD-1 mouse strains under terminal and survival surgical protocols approved by AAALAC-accredited institutions. All components comply with EU Medical Device Regulation (MDR 2017/745) Class I non-sterile designation and meet ASTM F1800-22 specifications for microsurgical instrument performance. Sterilization is validated per EN 554 and ISO 17665-1 using saturated steam cycles; ethylene oxide or low-temperature hydrogen peroxide plasma sterilization is not recommended due to material compatibility constraints. Instruments are compatible with standard laminar flow biosafety cabinets (Class II A2) and stereomicroscope-integrated surgical workstations (e.g., Leica M80, Zeiss Stemi 508).
Software & Data Management
While the SP1008-M set is a purely mechanical instrument collection with no embedded electronics or firmware, its design supports full integration into digital surgical workflow platforms. Each instrument is laser-engraved with a unique alphanumeric identifier (e.g., “SP1008-M-001”) for inventory tracking in LabVantage LIMS or Quartzy. Usage logs—including sterilization cycle timestamps, operator ID, and procedure date—can be linked to animal study IDs in StudyLog or eProtocol systems to satisfy FDA 21 CFR Part 11 audit trail requirements for preclinical GLP studies. Suture lot numbers and coagulation kit calibration certificates are provided in the accompanying Certificate of Conformance (CoC), issued per ISO 9001:2015.
Applications
- Survival endotracheal intubation for chronic respiratory disease modeling (e.g., COPD, ARDS, pulmonary fibrosis)
- Acute ventilatory support during intratracheal instillation of pathogens, nanoparticles, or therapeutic aerosols
- Combined thoracotomy and mechanical ventilation in cardiac ischemia-reperfusion models
- Pharmacodynamic assessment of neuromuscular blocking agents (e.g., rocuronium, vecuronium) under controlled ventilation
- IACUC-mandated refinement of inhalational anesthesia protocols using isoflurane-oxygen mixtures delivered via precision vaporizers (e.g., Matrx VIP 3000)
FAQ
Is this set suitable for rats or larger rodents?
No. The SP1008-M is dimensionally optimized for mice only. For rat applications (200–500 g), refer to the SP1008-R variant with extended-length instruments and reinforced handle ergonomics.
Are the instruments supplied sterile?
No. The set is provided non-sterile and requires terminal sterilization prior to first use. Autoclaving validation data and load configuration diagrams are included in the technical dossier.
Can the suture materials be substituted with absorbable alternatives?
Yes. The #2-O needle and 2/0 suture are supplied as non-absorbable polypropylene (USP/EN ISO 10993-1 certified). Alternative sutures—including fast-absorbing polyglycolic acid (PGA) or slow-absorbing polydioxanone (PDS)—may be used if validated for murine tracheal repair in pilot studies.
Does the set include a laryngoscope or endotracheal tube?
No. Visualization and intubation devices (e.g., rigid 1.0 mm pediatric laryngoscope blades, 18–20 G IV catheters modified as tracheal cannulas) are not included and must be selected based on institutional SOPs and animal weight stratification.
