Hanuo HND400 Visual Nitrogen Evaporator

Overview

The Hanuo HND400 Visual Nitrogen Evaporator is a precision-engineered dry-block concentrator designed for reproducible, oxygen-free solvent evaporation in analytical sample preparation workflows. It operates on the principle of controlled nitrogen gas impingement—directing a laminar, adjustable stream of inert gas across the surface of heated liquid samples to accelerate solvent volatilization while minimizing thermal degradation and oxidation. Unlike water-bath evaporators, the HND400 employs a solid aluminum heating block with high thermal conductivity and uniform heat distribution, enabling rapid temperature equilibration and stable setpoint maintenance across all 12 sample positions. Its transparent front panel and recessed tube slots allow uninterrupted visual monitoring of sample volume reduction—a critical feature for endpoint determination in quantitative residue analysis. The system is engineered for compliance with routine laboratory quality requirements, supporting trace-level analyte recovery in regulated environments where process consistency and documentation integrity are essential.

Key Features

• Dry-block heating architecture with machined aluminum module (single interchangeable block) ensuring fast thermal response and ±0.5°C uniformity across all positions
• Microprocessor-based PID temperature control with digital display (0.1°C resolution), programmable setpoint range from ambient +5°C to 160°C
• Independent, height-adjustable gas nozzles (200 mm vertical travel) with individual flow regulation—enabling precise gas delivery without cross-contamination
• Integrated visual observation zone: recessed tube slots and optically clear front shield permit real-time assessment of solvent meniscus and concentration endpoint
• Modular tube compatibility: seven standardized aluminum blocks available (10.5–20.5 mm diameter, 50 mm depth), each supporting 12 samples
• Programmable timer with dual-mode operation: fixed-duration (1–99 h 59 min) or continuous run; auto-shutdown upon timer expiry
• Safety-certified design: over-temperature protection, grounded chassis, and low-EMI power supply compliant with IEC 61010-1 for laboratory use

Sample Compatibility & Compliance

The HND400 accommodates standard borosilicate glass test tubes, culture tubes, and conical-bottom vials within the specified diameter and depth ranges. Its inert nitrogen environment preserves thermolabile compounds—including pesticides, endocrine disruptors, pharmaceutical metabolites, and volatile organic compounds—during concentration. The instrument supports method development aligned with ASTM D5845 (pesticide residue analysis), ISO 17025 documentation practices, and GLP-compliant sample preparation protocols. While not inherently 21 CFR Part 11–validated, its digital temperature logging (via optional RS232/USB interface) enables integration into validated lab information management systems (LIMS) when paired with audit-trail-capable software. All electrical components meet CE marking requirements for EMC and safety (EN 61326-1, EN 61010-1).

Software & Data Management

The HND400 operates as a standalone instrument with embedded firmware controlling temperature, timing, and gas delivery logic. For data traceability, an optional serial or USB interface permits connection to host PCs running third-party acquisition software (e.g., LabVIEW, Python-based logging tools). Temperature setpoints, actual block readings, timer status, and error codes can be streamed at user-defined intervals (1–60 s), generating timestamped CSV logs suitable for QC review and regulatory submission. No proprietary software is bundled; this open-architecture approach ensures compatibility with existing laboratory informatics infrastructure and avoids vendor lock-in during method transfer or multi-instrument fleet deployment.

Applications

• Residue analysis: Pre-concentration of pesticide extracts from fruits, vegetables, cereals, and plant matrices prior to GC-ECD or LC-MS/MS quantification
• Environmental testing: Cleanup and concentration of PAHs, PCBs, and organochlorines from drinking water, groundwater, and wastewater extracts
• Clinical and forensic toxicology: Solvent exchange and volume reduction of plasma, urine, or tissue homogenates prior to derivatization or instrumental analysis
• Pharmaceutical R&D: High-throughput sample cleanup in dissolution testing, stability studies, and herbal extract standardization
• Food safety screening: Concentration of mycotoxin, veterinary drug, or flavor compound extracts from dairy, alcoholic beverages, and infant formula

FAQ

What is the maximum recommended operating temperature for prolonged use?
The HND400 is rated for continuous operation up to 120°C; extended use above this temperature may reduce long-term heater element service life and affect calibration stability.
Can multiple gas sources be connected simultaneously?
No—the instrument features a single inlet manifold with integrated pressure regulator (0.1 MPa max); external gas manifolds must be used to supply multiple units.
Is calibration verification supported out-of-the-box?
Yes: the unit includes a dedicated PT100 sensor port for external reference probe insertion, enabling on-site temperature validation per ISO/IEC 17025 Section 6.4.10.
Are replacement heating blocks available for non-standard tube formats?
Custom-machined aluminum blocks can be ordered directly from Hanuo Engineering Services, subject to minimum order quantity and lead time confirmation.
Does the system include gas filtration or moisture removal?
No—users must supply laboratory-grade nitrogen (≥99.998% purity) with inline particulate and hydrocarbon filters; optional desiccant traps are recommended for humidity-sensitive applications.