Hanuo ULT-40-328L Ultra-Low Temperature Freezer
| Brand | Hanuo |
|---|---|
| Origin | Shanghai, China |
| Model | ULT-40-328L |
| Effective Volume | 328 L |
| Internal Dimensions (W×D×H) | 509 × 519 × 1393 mm |
| External Dimensions (W×D×H) | 673 × 676 × 1886 mm |
| Power Supply | 220 V, 50 Hz |
| Rated Power | 620 W |
| Operating Temperature Range | –10 °C to –40 °C |
| Net Weight | 128 kg |
Overview
The Hanuo ULT-40-328L is a vertically oriented ultra-low temperature freezer engineered for reliable, energy-efficient long-term storage of biological specimens, reagents, vaccines, and diagnostic samples at stable temperatures between –10 °C and –40 °C. Unlike cryogenic freezers operating below –60 °C, this model targets applications where deep freezing is required—but not at liquid nitrogen or ultra-deep cryo levels—making it ideal for blood banks, clinical laboratories, public health institutes, and life science research facilities requiring consistent thermal integrity without excessive energy demand. Its dual-stage cascade refrigeration system ensures rapid pull-down times and high thermal stability (< ±2 °C uniformity across the chamber), while the microprocessor-controlled PID temperature management system continuously monitors and adjusts compressor output, defrost cycles, and fan speed to maintain setpoint accuracy under variable ambient conditions (10–32 °C).
Key Features
- Vertically configured cabinet design with ergonomic door opening and full-height internal shelving for optimal space utilization in constrained laboratory environments.
- High-efficiency cascade refrigeration architecture using environmentally compliant R404A/R23 mixed refrigerants, minimizing global warming potential (GWP) relative to legacy systems.
- Triple-layer insulated door with magnetic gasket seal and vacuum-insulated panel (VIP) technology in side walls and ceiling to reduce heat ingress and improve energy efficiency (≤1.8 kWh/24h typical consumption).
- Real-time temperature logging via built-in RS485 interface; compatible with Modbus RTU protocol for integration into centralized lab monitoring networks (e.g., LabVantage, Thermo Fisher SampleManager).
- Alarm system with audible/visual alerts for high-temperature deviation (>±3 °C), door ajar, power failure, and sensor fault—configurable thresholds support ISO 15197 and CLIA-compliant operational protocols.
- Stainless steel interior (304 grade) with rounded corners and seamless welds for easy decontamination and compliance with biosafety Level 2 (BSL-2) cleaning standards.
Sample Compatibility & Compliance
The ULT-40-328L accommodates standard specimen storage configurations including cryoboxes (e.g., 10×10 grid formats), racked cryovials (0.5–5.0 mL), plasma bags, tissue cassettes, and pre-filled syringes. Its uniform temperature distribution meets ASTM F745-22 requirements for performance verification of low-temperature medical refrigerators. The unit is CE-marked per EN 61000-6-3 (EMC) and EN 61000-6-1 (immunity), and conforms to IEC 61010-1:2010 for safety in laboratory equipment. While not certified to FDA 21 CFR Part 11 out-of-the-box, its data logging function supports audit-ready traceability when paired with validated third-party software enabling electronic signature and change control workflows aligned with GLP/GMP documentation practices.
Software & Data Management
Embedded firmware supports local data retention of up to 30 days of 10-minute interval temperature records (timestamped, non-volatile memory). Optional Ethernet or Wi-Fi module enables remote access via secure HTTPS web interface or SNMP v3 polling. Exportable CSV logs include ambient temperature, compressor run time, defrost frequency, and alarm history—structured to align with LIS/LIMS ingestion templates. Firmware updates are performed via USB drive with cryptographic signature verification to prevent unauthorized modification, supporting regulatory readiness for CAP inspections and ANVISA/CFDA audits.
Applications
- Blood bank inventory management: long-term preservation of red blood cells, platelet concentrates, and frozen plasma units per AABB Standards.
- Vaccine cold chain staging: interim holding of mRNA, viral vector, and adjuvanted vaccines prior to distribution under WHO PQ guidelines.
- Biobanking operations: archival storage of human tissue sections, PBMC isolates, and FFPE blocks where –40 °C provides sufficient stabilization without ice recrystallization risk associated with repeated freeze-thaw.
- QC/QA laboratories: controlled environment for stability testing of pharmaceutical excipients and diagnostic reagents per ICH Q1A(R2).
- Marine bioprospecting: onboard storage of deep-sea microbial isolates and environmental DNA samples during extended research cruises.
FAQ
What is the recommended ambient operating temperature range for this freezer?
The unit is rated for continuous operation in ambient environments between 10 °C and 32 °C with maximum relative humidity ≤80% non-condensing.
Does the ULT-40-328L support external temperature monitoring integration?
Yes—via RS485 Modbus RTU port; optional gateway modules enable BACnet/IP or MQTT publishing for building management system (BMS) interoperability.
Is validation documentation (IQ/OQ/PQ) provided with the unit?
Factory-installed IQ/OQ documentation is available upon request; PQ protocols must be executed on-site by qualified personnel per ISO/IEC 17025 requirements.
Can the internal shelving be reconfigured for custom rack systems?
All shelves are adjustable on 25-mm pitch rails and support static loads up to 35 kg per shelf; third-party racks require mechanical compatibility verification prior to installation.
What maintenance intervals are recommended?
Condenser coil cleaning every 3 months in dusty environments; annual calibration of temperature sensors against NIST-traceable reference probes; compressor oil analysis every 24 months under continuous operation.
