Hanuo HNDK200-2 Dry-Block Nitrogen Evaporator
| Brand | Hanuo |
|---|---|
| Origin | Shanghai, China |
| Model | HNDK200-2 |
| Heating Method | Dry-block heating |
| Temperature Range | Ambient +5 °C to 150 °C |
| Temperature Stability | ±0.5 °C (at 100 °C) |
| Tube Compatibility | 6–40 mm diameter |
| Nitrogen Flow Rate | 0–10 L/min |
| Sample Capacity | 24-position (modular configuration) |
| Heating Power | 400 W |
| Display Resolution | 0.1 °C |
| Timer Range | 0–99 h 59 min |
| Max Operating Pressure | ≤0.1 MPa |
| Dimensions (W×D×H) | 280 × 220 × 500 mm |
Overview
The Hanuo HNDK200-2 Dry-Block Nitrogen Evaporator is an engineered solution for parallel solvent removal and sample concentration in analytical laboratories. It operates on the principle of inert gas-assisted evaporation—introducing a controlled stream of nitrogen across the surface of heated liquid samples to accelerate solvent volatilization while minimizing oxidation, thermal degradation, or cross-contamination. Unlike rotary evaporation—which processes one or few samples sequentially—the HNDK200-2 enables simultaneous concentration of up to 24 samples under identical, programmable thermal and gaseous conditions. Its dry-block heating architecture ensures rapid thermal response, uniform temperature distribution across the aluminum heating module, and precise control without reliance on oil baths or water jackets. Designed for integration into regulated workflows, the system supports method reproducibility required in pharmaceutical QC, environmental testing, clinical research, and food safety laboratories.
Key Features
- Dual independent 24-position dry-block heating modules with individual temperature control and real-time LED display (0.1 °C resolution)
- Adjustable nitrogen flow per channel (0–10 L/min total), with 12 individually controllable gas outlets to minimize gas consumption during partial-load operation
- Height-adjustable gas manifold assembly: vertical positioning accommodates varying solvent levels and enables safe operation inside fume hoods when handling volatile or toxic solvents
- Interchangeable tube holders compatible with standard microcentrifuge tubes (0.2 mL to 2 mL) and wider-diameter vials (6–40 mm); standard needle length: 150 mm
- Integrated safety architecture including over-temperature cutoff, automatic fault detection with audible/visual alarm, and thermal fuse protection
- Programmable timer (0–99 h 59 min) with countdown display and auto-shutdown function
- Front-panel digital interface with intuitive navigation; no external software required for basic operation
Sample Compatibility & Compliance
The HNDK200-2 is validated for use with common organic solvents (e.g., acetonitrile, methanol, ethyl acetate, dichloromethane) and aqueous matrices encountered in LC-MS, GC-MS, ELISA, and hormone assay preparation. Its inert nitrogen environment preserves labile analytes—including steroids, catecholamines, and certain peptides—during concentration. While not certified to ISO/IEC 17025 or FDA 21 CFR Part 11 out-of-the-box, the instrument’s deterministic temperature control (±0.5 °C stability at 100 °C), traceable calibration capability, and audit-ready operational logs (via optional RS232/USB data export) support alignment with GLP and GMP documentation requirements. Users may implement SOPs referencing ASTM D7217 (for solvent residue analysis) or USP chromatographic method validation where sample prep consistency is critical.
Software & Data Management
The HNDK200-2 operates as a standalone benchtop instrument with embedded firmware controlling all thermal and pneumatic parameters. Real-time temperature and timer values are displayed continuously on a high-contrast LED screen. For laboratories requiring electronic recordkeeping, optional serial (RS232) or USB connectivity enables time-stamped parameter logging—including setpoint, actual temperature, elapsed time, and gas flow status—to external PCs running compliant LIMS or ELN platforms. No proprietary software installation is required; raw ASCII data streams can be parsed directly into Excel or validated database systems. All settings retain memory after power cycling, supporting continuity across shifts and multi-day protocols.
Applications
- Routine concentration of extracts prior to LC-MS/MS analysis in bioanalytical labs (e.g., plasma, urine, tissue homogenates)
- High-throughput cleanup in environmental monitoring—concentrating pesticide residues from QuEChERS extracts
- Preparative step in forensic toxicology workflows involving benzodiazepines, opioids, or stimulants
- Standardization of calibration standards and QC reference materials across multiple concentration levels
- Parallel evaporation of derivatized amino acids or fatty acid methyl esters (FAMEs) in nutritional analysis
- Stabilization of thermally sensitive compounds (e.g., prostaglandins, nitrosamines) where vacuum or elevated heat must be avoided
FAQ
Is the HNDK200-2 suitable for use with chlorinated solvents such as chloroform or carbon tetrachloride?
Yes—provided the system is operated inside a certified fume hood and the nitrogen supply is oil-free and filtered to ISO 8573-1 Class 2 purity. The aluminum block and stainless-steel gas manifolds resist corrosion under standard exposure conditions.
Can the heating modules be calibrated independently?
Yes. Each dry-block module includes a dedicated PT100 sensor and PID controller. External calibration using NIST-traceable thermometers is supported via the access port beneath the block surface.
What maintenance is required to ensure long-term accuracy?
Annual verification of temperature uniformity (per ASTM E220) and flowmeter linearity is recommended. Clean gas needles regularly with ethanol and inspect O-rings for compression set every six months.
Does the unit comply with CE or UL safety standards?
The HNDK200-2 meets IEC 61010-1:2010 for laboratory electrical equipment. CE marking is applied for EU market placement; UL certification is not currently held but may be pursued per customer request.
