AS ONE GHW-3000 Vortex Mixer

Overview

The AS ONE GHW-3000 Vortex Mixer is a precision-engineered benchtop vortex shaker designed for consistent, repeatable sample homogenization in research, clinical, and quality control laboratories. Utilizing a high-efficiency eccentric drive mechanism, the instrument generates controlled orbital motion to induce rapid turbulent mixing—ideal for suspending precipitates, resuspending pellets, emulsifying low-viscosity solutions, and preparing samples prior to analysis (e.g., HPLC injection, ELISA plate preparation, or nucleic acid extraction). Its low-center-of-gravity mechanical architecture ensures minimal vibration transmission and operational stability—even during extended use at maximum speed—reducing risk of sample spillage and enhancing reproducibility across sequential runs.

Key Features

• Digitally displayed RPM setting with large, high-contrast LED readout—enabling rapid verification of operating speed without visual strain.
• Dual-mode operation: touch-activated mode for momentary mixing (ideal for intermittent agitation of tubes during centrifugation pauses) and continuous mode for sustained homogenization protocols.
• Robust aluminum alloy housing with anti-slip rubberized base—optimized for secure placement on laminar flow hoods, biosafety cabinets, or standard lab benches.
• Intelligent motor control system maintains consistent rotational velocity across load variations (1–50 mL tube capacity), minimizing speed drift under mechanical load.
• Compliance-ready design: fully compatible with audit-trail documentation requirements when integrated into validated workflows governed by ISO/IEC 17025, CLIA, or FDA 21 CFR Part 11–aligned environments (when paired with compliant data logging systems).

Sample Compatibility & Compliance

The GHW-3000 accommodates standard microcentrifuge tubes (0.2–2.0 mL), conical-bottom tubes (15–50 mL), and round-bottom culture tubes via its universal platform accessory. The oscillation amplitude (4 mm orbital displacement) is calibrated to deliver effective mixing without inducing excessive foaming or shear-induced denaturation in protein or cell-based samples. All electrical components conform to IEC 61010-1 Edition 3 for laboratory equipment safety, including protection against electric shock, mechanical hazards, and abnormal temperature rise. The unit carries PSE certification for the Japanese market and CE marking for European Economic Area distribution—ensuring traceable compliance with electromagnetic compatibility (EMC) and low-voltage directives.

Software & Data Management

While the GHW-3000 operates as a standalone analog-digital hybrid device without embedded firmware or network connectivity, its operational parameters—including speed setting, activation mode, and cumulative runtime—are fully documentable via external lab notebook entries or LIMS-integrated electronic batch records. For regulated environments requiring electronic audit trails, users may integrate the mixer into validated workflows using time-stamped video monitoring or IoT-enabled power-metering devices that log activation events and duration. The absence of proprietary software reduces cybersecurity surface area and simplifies qualification (IQ/OQ/PQ) activities during equipment validation per ASTM E2500 or EU Annex 15 guidelines.

Applications

• Routine resuspension of bacterial cell pellets post-centrifugation in molecular biology workflows.
• Homogenization of reagent stocks containing insoluble components (e.g., enzyme inhibitors, buffer salts, or lyophilized standards).
• Pre-analytical preparation of clinical specimens—including serum separation tubes, EDTA whole blood dilutions, and urine sediment suspensions—prior to automated immunoassay or urinalysis platforms.
• Supporting QC testing in pharmaceutical manufacturing: uniform dispersion of excipients in suspension formulations prior to viscosity or particle size analysis.
• Facilitating rapid solvent mixing in synthetic chemistry labs where inert-atmosphere vial agitation is required (when used inside gloveboxes with appropriate feedthroughs).

FAQ

What is the minimum and maximum tube volume supported?
The GHW-3000 is optimized for tubes ranging from 0.2 mL PCR strips to 50 mL conical centrifuge tubes. Effective vortexing is achieved across this range when using the included universal platform attachment.
Is speed calibration traceable to national standards?
Yes—AS ONE provides optional factory calibration certificates (NIST-traceable tachometer verification) upon request, supporting metrological traceability per ISO/IEC 17025 Clause 6.5.
Can the unit be operated inside a cold room or incubator?
It is rated for ambient operation between 5 °C and 40 °C and relative humidity ≤80% non-condensing. Extended use below 15 °C requires verification of motor lubricant performance and display responsiveness under specific environmental conditions.
Does the mixer meet FDA requirements for use in GMP environments?
The hardware design complies with general GMP facility equipment criteria (cleanability, material compatibility, absence of shedding parts). Formal GMP suitability requires site-specific risk assessment and inclusion in the facility’s equipment qualification protocol.
How often does preventive maintenance require service?
AS ONE recommends biannual visual inspection of the drive coupling and platform mounting screws; no scheduled lubrication or internal component replacement is specified within the first 5 years of typical laboratory use.