Millipore Elix 100 Laboratory Pure Water System
| Brand | Millipore |
|---|---|
| Origin | France |
| Model | Elix 100 |
| Flow Rate | 100 L/h (±15%, at 7–30°C) |
| Resistivity | >5 MΩ·cm (at 25°C, temperature-compensated) |
| Conductivity | <0.2 µS/cm (at 25°C, temperature-compensated) |
| TOC | <30 ppb |
| Bacterial Count | <10 CFU/mL |
| Silica Removal Efficiency | >99.9% |
| Recovery Rate | up to 50% |
| Dimensions (H×W×D) | 73.4 × 66.2 × 44.1 cm |
| Operating Weight | 62 kg |
Overview
The Millipore Elix 100 is a high-capacity, modular laboratory pure water system engineered for continuous production of Type II analytical-grade water per ASTM D1193, ISO 3696:1995, CLSI (formerly NCCLS) guidelines, and pharmacopoeial standards including USP Purified Water and Ph. Eur. Purified Water. Operating on a multi-stage purification architecture—comprising pretreatment, reverse osmosis (RO), electrodeionization (EDI) via patented Elix continuous current deionization technology, and post-treatment with integrated UV irradiation—the system delivers consistent, low-conductivity water without chemical regeneration or downtime. Designed for integration into centralized distribution networks, the Elix 100 supports both point-of-use and loop-fed configurations, serving as primary feedwater for downstream ultra-pure systems (e.g., Milli-Q® or Super-Q® platforms) and direct applications requiring high-reliability Type II water.
Key Features
- Patented Elix continuous current deionization module enables uninterrupted resin regeneration, eliminating manual cartridge replacement and minimizing operational interruptions.
- Integrated real-time monitoring: dual-sensor conductivity/resistivity meter (temperature-compensated to 25°C) and online TOC analyzer (<30 ppb detection limit) ensure continuous compliance verification.
- UV lamp (185/254 nm) integrated in the final polishing stage suppresses microbial regrowth and photo-oxidizes trace organics, critical for cell culture media preparation and sensitive biochemical assays.
- Modular pretreatment design accommodates variable municipal feedwater quality; scalable prefilter and softening cartridges are field-replaceable without tools.
- No external softener required for most municipal supplies—reducing footprint, maintenance complexity, and total cost of ownership.
- Full-system control interface manages internal purification stages and external distribution loop parameters—including pump status, UV intensity, ASM (air sensor module) diagnostics, and loop-resistivity mapping.
Sample Compatibility & Compliance
The Elix 100 produces water meeting or exceeding international specifications for Type II laboratory water. Its output consistently achieves resistivity >5 MΩ·cm (25°C), conductivity <0.2 µS/cm, TOC <30 ppb, and bacterial load <10 CFU/mL—validated across diverse inlet conditions (including CO2-rich feedwater up to 30 ppm). The system supports GLP- and GMP-aligned workflows through audit-trail-capable logging of all critical parameters (flow, pressure, resistivity, TOC, UV dose), compliant with FDA 21 CFR Part 11 requirements when paired with compatible data management software. It is routinely deployed in regulated environments for pharmaceutical purified water generation (per USP ), QC/QA buffer preparation, and as feedwater for ISO/IEC 17025-accredited testing laboratories.
Software & Data Management
The Elix 100 features an embedded controller with Ethernet connectivity and optional integration into Millipore’s LabManager™ or third-party LIMS platforms. All operational events—including alarm triggers, maintenance alerts, sensor calibration logs, and daily performance summaries—are timestamped and exportable in CSV or PDF format. Historical data retention supports root-cause analysis during investigations and satisfies regulatory documentation requirements under ISO 9001, ISO/IEC 17025, and EU Annex 11. Optional remote monitoring enables real-time oversight of multiple Elix units across distributed lab sites, facilitating predictive maintenance scheduling and centralized quality assurance oversight.
Applications
- Preparation of microbiological growth media and sterile irrigation solutions
- Formulation of HPLC mobile phases, electrophoresis buffers, and ELISA reagents
- Feedwater supply for Milli-Q® IQ 7000, Milli-Q® Integral, or Super-Q® ultrapure systems
- Pharmaceutical manufacturing support: Purified Water (PW) for non-sterile API synthesis and equipment rinsing
- Hydroponic and plant tissue culture applications requiring low ionic background
- Calibration and validation of analytical instruments (e.g., ICP-MS, LC-MS, AAS)
- Routine cleaning of glassware and laboratory equipment where mineral residue must be minimized
FAQ
What is the maximum daily output capacity of the Elix 100 system?
The Elix 100 is rated for continuous operation delivering up to 4,000 L/day of Type II pure water under standard ambient conditions (7–30°C inlet temperature). Actual throughput depends on feedwater quality, pressure, and temperature.
Does the Elix 100 require a dedicated water softener?
No—its robust pretreatment and RO-EDI architecture tolerates typical municipal hardness levels without external softening, though optional softeners may be added for high-scaling feed sources.
Can the Elix 100 be integrated into an existing purified water distribution loop?
Yes—the system includes configurable loop interface modules (pump, ASM, TOC/resistivity sensors) and supports both pressurized and gravity-fed ring mains.
How often does the Elix continuous deionization module require service?
The Elix EDI stack operates continuously with no consumable resins; routine maintenance includes quarterly UV lamp inspection, annual RO membrane assessment, and cartridge replacement based on differential pressure and feedwater analysis.
Is the Elix 100 compliant with pharmacopoeial purified water monographs?
Yes—its validated output meets USP Purified Water, Ph. Eur. Purified Water, and JP Purified Water specifications when installed and operated per Millipore’s PQ/OQ protocols and maintained under documented SOPs.
