Yoyi LHS-250SC Temperature and Humidity Controlled Chamber (250 L Vertical Environmental Test Chamber)

Overview

The Yoyi LHS-250SC is a vertically oriented, microprocessor-controlled temperature and humidity chamber engineered for precise environmental simulation in laboratory and industrial quality assurance settings. It operates on the principle of active thermoelectric and vapor-phase humidification control, integrating forced-air convection with optimized airflow distribution to maintain stable thermal and hygrometric conditions across its 250 L working volume. Designed for reproducible long-term exposure testing, the chamber supports standardized stability studies, accelerated aging protocols, shelf-life validation, and environmental stress screening in accordance with international regulatory frameworks—including pharmaceutical stability testing (ICH Q1), material durability assessment (ASTM D4332, ISO 22309), and biocompatibility preconditioning (ISO 10993-12). Its dual-layer insulated door with sealed observation window minimizes thermal leakage during visual monitoring, while the stainless-steel interior—featuring seamless, radius-corner construction—ensures cleanability and resistance to corrosion from repeated condensation cycles.

Key Features

• Stainless-steel interior chamber with mirror-finish surface and fully rounded internal corners for enhanced sanitation and residue-free cleaning.
• CFC-free refrigeration system utilizing R134a and R406a blends, delivering energy-efficient cooling performance with low global warming potential (GWP).
• Integrated ultrasonic-free electric heating rod humidification system with built-in water reservoir, calibrated against traceable humidity sensors meeting ISO/IEC 17025 reference standards.
• Intelligent PID control architecture supporting up to 99 programmable cycles, each comprising 30 user-defined segments with independent setpoints for temperature, humidity, and duration (max. 99 h 99 min per segment).
• High-efficiency air circulation design with rear-mounted centrifugal blower and directional ductwork, ensuring ≤±1 °C temperature uniformity and ≤±5 %RH humidity uniformity at steady state (per GB/T 2424.6–2006 test methodology).
• Mobile chassis with four swivel casters and locking leveling feet, enabling secure repositioning without compromising vibration isolation or operational stability.
• Large backlit LCD interface with intuitive menu navigation, real-time parameter display, and password-protected configuration access for audit-ready operation.

Sample Compatibility & Compliance

The LHS-250SC accommodates a broad range of sample formats—including Petri dishes, vials, trays, electronic assemblies, polymer specimens, and packaged medical devices—within its adjustable stainless-steel shelving system (standard configuration: two load-bearing shelves, height-adjustable in 25 mm increments). The chamber’s structural integrity and environmental fidelity have been validated under no-load conditions per GB/T 10586–2006 (Wet Heat Test Chamber Technical Requirements) and GB/T 2424.6–2006 (Performance Verification of Temperature/Humidity Chambers). It meets essential criteria for GLP-compliant laboratories, including data traceability, alarm logging, and deviation reporting. Optional RS485 communication interface enables integration into centralized environmental monitoring systems compliant with FDA 21 CFR Part 11 requirements when paired with validated third-party software platforms.

Software & Data Management

While the embedded controller provides local program execution and real-time parameter visualization, optional RS485 serial connectivity supports bidirectional communication with external PC-based data acquisition systems. Users may export time-stamped temperature/humidity logs (CSV format) for post-test analysis or integrate chamber status signals into SCADA environments. The controller retains full operational history—including power interruption events, alarm triggers, and manual override records—for minimum 30 days without external storage. For regulated environments, optional embedded printer (thermal, 58 mm width) delivers hard-copy audit trails synchronized with chamber timestamps, satisfying documentation requirements under ISO 13485 and EU Annex 11.

Applications

• Pharmaceutical stability testing (ICH Q1A–Q1E), including long-term, intermediate, and accelerated conditions.
• Biological sample conditioning prior to microbiological assay or cell culture initiation.
• Material aging studies for polymers, adhesives, coatings, and elastomers under controlled thermo-hygrometric stress.
• Electronics reliability testing: moisture sensitivity level (MSL) preconditioning per J-STD-020 and JEDEC standards.
• Food packaging permeability evaluation and shelf-life modeling under variable RH profiles.
• Textile and leather conditioning per ASTM D1776 and ISO 139 for tensile, colorfastness, and dimensional stability testing.
• Environmental qualification of medical devices per ISO 11607-1 and AAMI TIR17.

FAQ

What is the maximum allowable ambient operating temperature for the LHS-250SC?
The chamber is rated for continuous operation in ambient environments between 15 °C and 30 °C, with relative humidity not exceeding 80 %RH (non-condensing), as specified in GB/T 10586–2006.
Does the unit support validation documentation (IQ/OQ/PQ)?
Yes—Yoyi provides factory calibration certificates traceable to NIM (National Institute of Metrology, China), along with standard OQ test protocols aligned with GB/T 2424.6–2006. Custom IQ/PQ support is available upon request with qualified third-party service partners.
Can the chamber operate continuously at 60 °C and 85 %RH?
Yes—the LHS-250SC is designed for uninterrupted operation across its full specified range; however, sustained operation at extreme upper limits may reduce compressor duty cycle longevity and requires adequate ventilation clearance (≥100 mm on all sides).
Is the humidity sensor field-replaceable and NIST-traceable?
The integrated capacitive humidity sensor is user-serviceable and supplied with a calibration certificate referencing national metrological standards; annual recalibration is recommended for GxP applications.
What safety protections are built into the system?
Standard safeguards include over-temperature cut-off (independent mechanical limiter), compressor high-pressure shutdown, door-open alarm, water reservoir dry-run protection, and real-time fault code display on the main interface.