Circular Dichroism Spectrometer
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| Brand | Applied Photophysics |
|---|---|
| Origin | United Kingdom |
| Instrument Type | Circular Dichroism (CD) Spectrometer |
| Model Designation | Chirascan |
| Compliance | CE, UKCA |
| Optical Path | Dual-beam, photoelastic modulator (PEM)-based |
| Wavelength Range | 170–900 nm |
| Temperature Control Range | −40 °C to +120 °C (with optional cryostat & Peltier units) |
| Data Acquisition Rate | Up to 500 points/sec |
| Signal-to-Noise Ratio | <0.005 mdeg (at 220 nm, 1 nm bandwidth, 1 s time constant) |
| Brand | Applied Photophysics |
|---|---|
| Origin | United Kingdom |
| Manufacturer Type | Authorized Distributor |
| Product Category | Imported Instrument |
| Model | Chirascan CPL |
| Instrument Type | Circular Dichroism / Circularly Polarized Luminescence Spectrometer |
| Optical Path Configurations | 90° and 180° fluorescence detection modes |
| Excitation Range | 170–900 nm (deep-UV capable with N₂ purge) |
| Monochromator | F/7 double-prism design |
| Polarization Optics | Dual high-fidelity polarization prisms |
| Data Acquisition | Digital signal processing (DSP) architecture with adaptive integration time control |
| Sample Compatibility | Liquids, powders, films, gels, turbid suspensions, and opaque solids |
| Compliance | Designed for GLP/GMP-aligned workflows |
| Brand | Applied Photophysics |
|---|---|
| Origin | United Kingdom |
| Manufacturer Type | Authorized Distributor |
| Instrument Type | Circular Dichroism (CD) and Synchronous Fluorescence Spectrometer |
| Model | Chirascan Plus |
| Detection Technology | Large-Area Avalanche Photodiode (LAAPD) Detector |
| Wavelength Range | 170–900 nm (CD), 200–900 nm (Fluorescence) |
| Sensitivity | Enhanced vs. standard Chirascan (LAAPD-enabled) |
| Automation | Optional unattended high-throughput configuration |
| Brand | Applied Photophysics |
|---|---|
| Origin | United Kingdom |
| Instrument Type | Circular Dichroism (CD) Spectrometer |
| Model | Chirascan Q100 CD |
| Detection Range | 170–1700 nm |
| Optical Design | Dual Rochon Prism Monochromator |
| Detector Options | LAAPD (1200 nm), InGaAs (up to 1700 nm) |
| Automation Level | Fully Integrated, Unattended Operation |
| Compliance | Designed for GLP/GMP-aligned biophysical characterization |
| Brand | Applied Photophysics |
|---|---|
| Origin | United Kingdom |
| Model | Stopped-Flow Accessory for Chirascan CD Spectrometer |
| Instrument Type | Circular Dichroism (CD) |
| Dead Time | ≤1.5 ms |
| Cuvette Volume | 20 µL (switchable 2 mm / 10 mm pathlength) |
| Compatibility | Fully integrated with Chirascan series CD spectrometers |
| Detection Modes | Stopped-flow CD, absorption, fluorescence, fluorescence polarization, diode array, quench-flow |
| Optional Modules | Multi-channel rapid mixing system, dual fluorescence detection, time-resolved absorption |
| Brand | Applied Photophysics |
|---|---|
| Origin | United Kingdom |
| Manufacturer Type | Authorized Distributor |
| Product Category | Imported Instrument |
| Model | Chirascan V100 |
| Instrument Type | Circular Dichroism (CD) Spectrometer |
| Price Range | USD 170,000 – 390,000 (estimated FOB UK) |
| Brand | Applied Photophysics |
|---|---|
| Origin | United Kingdom |
| Model | SX20 |
| Instrument Type | Stopped-Flow CD/Fluorescence/Absorption Spectrometer |
| Compliance | Designed for GLP/GMP-aligned laboratories |
| Software | Pro-Data acquisition and kinetic analysis suite (FDA 21 CFR Part 11 compliant audit trail optional) |
| Detector Options | Photodiode array, dual photomultiplier tubes, fluorescence polarization module, CD-compatible stopped-flow cell |
| Mixing Systems | Single-, double-, or triple-syringe configurations |
| Temperature Control | ±0.1 °C over 5–40 °C range |
| Data Acquisition Rate | Up to 100 kHz (depending on detector configuration) |
| Brand | Applied Photophysics |
|---|---|
| Origin | United Kingdom |
| Model | SX20 |
| Instrument Type | Circular Dichroism (CD) Stopped-Flow Spectrometer |
| Detection Principle | Far-UV to Near-UV CD spectroscopy (170–450 nm) |
| Flow Precision | ≤1% RSD per injection |
| Dead Time | <1.0 ms (with optimized cell and drive system) |
| Temperature Control Range | 4–80 °C (±0.1 °C stability) |
| Data Acquisition Rate | Up to 20,000 points/sec (CD signal at single wavelength) |
| Compliance | ASTM E2915, ISO/IEC 17025–compliant operation framework, supports 21 CFR Part 11–ready audit trail via KineticStudio software |
| Brand | Applied Photophysics |
|---|---|
| Origin | United Kingdom |
| Model | SX20 |
| Instrument Type | Circular Dichroism (CD) Stopped-Flow Spectrometer |
| Application Domain | Transient Kinetics, Pre-Steady-State Reaction Analysis |
| Compliance Context | ASTM E259, ISO 17025 (for kinetic method validation), GLP/GMP-ready data audit trail support |
| Brand | Applied Photophysics |
|---|---|
| Origin | United Kingdom |
| Model | SX20 |
| Instrument Type | Circular Dichroism (CD) Stopped-Flow Spectrometer |
| Detection Options | Diode Array, Dual Fluorescence, Fluorescence Polarization, Quench-Flow, Multi-Channel Sequential Mixing, CD-Stopped-Flow Module |
| Brand | Bio-logic |
|---|---|
| Origin | France |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | EKKO |
| Price Range | USD 68,000 – 136,000 (est.) |
| Instrument Type | Circular Dichroism (CD) Spectrometer |
| Wavelength Range | 185–850 nm |
| Spectral Bandwidth | 1 nm (full range) |
| Noise Level | ≤ 0.05 mdeg |
| Plate Formats | Standard 96-well microplates (optional 384-well support) |
| Modulation Frequency | 50 kHz |
| Single-Wavelength Throughput | ~2 min per 96-well plate |
| Multi-Wavelength Scan (e.g., 210–350 nm, 5 nm step) | ~30 sec per well (~50 min total) |
| Full-Spectrum Scan (185–850 nm, 1 nm step) | ~11 min per well (~18 h total) |
| Brand | Bio-Logic |
|---|---|
| Origin | France |
| Model | MOS-450 |
| Instrument Type | Circular Dichroism (CD) Spectrometer |
| Light Sources | 150 W Xenon Lamp + 150 W Mercury-Xenon Lamp |
| Wavelength Range | 165–900 nm |
| Wavelength Accuracy | ±0.1 nm (165–900 nm) |
| Optical System | Dual Grating (1200 grooves/mm) |
| Stray Light | < 2 × 10⁻⁴ % (at 200 nm) |
| Noise Level (CD) | 0.01 mdeg |
| Baseline Stability | < 0.01 mdeg/hr |
| Data Acquisition Rate | 10 µs to 1000 s per point |
| Stopped-Flow Unit | Triple-/Quadruple-Channel Mixing, Independent Stepper-Motor Control per Channel |
| Minimum Injection Volume | 10 µL |
| Flow Rate per Channel | 0.01–1.0 mL/s |
| Mixing Ratio Range | Continuously Adjustable from 1:1 to 1:100 |
| Minimum Dead Time | 0.25 ms (with micro-volume detection cell) |
| Expandable Modules | Cryo-Quench, Sub-Zero Stopped-Flow, Temperature-Jump (T-Jump), Auto-Titration, In-Situ Micro-Conductivity Detection |
| Brand | Bio-Logic |
|---|---|
| Origin | France |
| Model | MOS-500 |
| Instrument Type | Circular Dichroism (CD) Spectrometer |
| Light Sources | 150 W Xenon Lamp + 150 W Mercury-Xenon Lamp |
| Detection Modes | CD, UV-Vis Absorption, Fluorescence CD (FCD), Linear Dichroism (LD), Fluorescence Anisotropy |
| Wavelength Range | 163–950 nm (extendable to 1250 nm) |
| Wavelength Accuracy | ±0.1 nm (163–1250 nm) |
| Optical System | Dual Grating Monochromator |
| Stray Light | <2 × 10⁻⁶ at 200 nm |
| Baseline Stability | 0.007 mdeg/hr |
| Maximum Scan Speed | 12,000 nm/min |
| Solid Sample Capability | Integrated Integrating Sphere for Diffuse Reflectance |
| Stopped-Flow Unit | Triple- or Quadruple-Channel Mixing with Independent Stepper-Motor Control |
| Minimum Injection Volume | 10 µL |
| Flow Rate Range | 0.01–40 mL/s |
| Mixing Ratio Range | Continuously Adjustable from 1:1 to 1:100 |
| Mixer Type | Spherical High-Efficiency Mixing Cell |
| Dead Time | 0.2 ms (with Microcell Accessory) |
| Expandable Modules | Cryo-Quench, Sub-Zero Stopped-Flow, Temperature-Jump (T-Jump), Automated Titration, Microconductivity Detection |
| Brand | BioTools |
|---|---|
| Origin | USA |
| Model | ChiralIR-2X |
| Instrument Type | Vibrational Circular Dichroism (VCD) Spectrometer |
| Spectral Range | 4000–850 cm⁻¹ (standard), optional extension to 10,000 cm⁻¹ (NIR) |
| Baseline Drift | < 2 × 10⁻⁵ AU |
| Signal-to-Noise Ratio | >3.6× improvement over single-source systems |
| Detector Continuous Operation | 30–48 hours |
| Optical Path | Fully automated alignment and calibration |
| Data Acquisition | Digital signal processing (no lock-in amplifiers or analog filtering required) |
| Sample Stage | SyncRoCell™ rotating sample cell platform |
| DualPEM™ capability | Optional upgrade for solid-sample VCD correction |
| Brand | Applied Photophysics |
|---|---|
| Origin | United Kingdom |
| Manufacturer Type | Authorized Distributor |
| Product Origin | Imported |
| Model | Hellma NexIII Cuvette Cleaning Solution |
| Instrument Category | Circular Dichroism (CD) Spectrometry |
| Price Range | USD 260–1,300 (ex-works, excluding VAT & shipping) |