DNA Synthesizer
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| Brand | Cytiva |
|---|---|
| Origin | Sweden |
| Model | ÄKTA oligosynt™ |
| Type | Fully Automated Solid-Phase Oligonucleotide Synthesizer |
| Synthesis Scale Range | 40 nmol to 1 µmol |
| Reagent Delivery Precision | ≤2% RSD |
| System Footprint | 600 × 650 × 700 mm (W × D × H) |
| Integrated Sensor Suite | Pressure, Mass Flow, Temperature, UV Absorbance, Conductivity |
| Compliance | Designed for GLP/GMP-aligned process development environments |
| Brand | Cytiva |
|---|---|
| Origin | Sweden |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | ÄKTA oligosynt™ |
| Price Range | USD 14,000 – 140,000 (est.) |
| Principle | Electrochemical Phosphoramidite Synthesis |
| Type | High-Throughput Benchtop Synthesizer |
| Synthesis Scale | 10 µmol – 12 mmol |
| Brand | Cytiva |
|---|---|
| Origin | Sweden |
| Instrument Type | High-Throughput |
| Synthesis Scale Range | 10–1800 µmol |
| Explosion-Proof Design | Yes |
| Industrial-Grade Components | Yes |
| Regulatory Compliance | GMP-Ready, Supports FDA 21 CFR Part 11 & EU Annex 11 |
| Software Platform | UNICORN® v7.x or later |
| Scalability | Linear lab-to-commercial scale-up |
| Annual Production Capacity | Up to hundreds of kilograms (kg/yr), extendable to metric tons under continuous operation |
| Brand | Cytiva |
|---|---|
| Origin | Sweden |
| Model | OligoProcess™ |
| Synthesis Scale | 10–1800 mmol per run |
| Regulatory Compliance | FDA 21 CFR Part 11, GMP-ready architecture |
| Software Platform | UNICORN 7.x or later |
| Column Technology | Flow-through synthesis columns (compatible with ÄKTA oligopilot plus and OligoPilot 400) |
| Construction | Industrial-grade, explosion-proof certified components |
| Application Scope | Clinical-phase development through commercial-scale cGMP manufacturing |
| Brand | JIZHOU |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Product Origin | Domestic (China) |
| Model | JZ-Series Fixed-Volume Stainless Steel Oligo Synthesis Columns |
| Volumes | 1.2 mL, 6.3 mL, 12 mL, 24 mL, 48 mL |
| Material | ASTM F138-certified 316L stainless steel |
| Column Dimensions | As per JZ-1001 to JZ-1005 specification table |
| Filter Type | Sintered metal frit (porosity: 5–10 µm) |
| Pressure Rating | ≤10 bar (static), compatible with standard phosphoramidite chemistry delivery systems |
| Sealing | Dual O-ring (FKM/Viton®) static seal assembly |
| Brand | JIZHOU |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Country of Origin | China |
| Model | Oligo Series |
| Pressure Rating | 2 MPa |
| Internal Diameter Options | 35 mm, 50 mm, 70 mm, 100 mm, 140 mm, 200 mm, 350 mm |
| Bed Height Range | 0–150 mm (standard), 50–300 mm (long-bed variants) |
| Column Volume Range | 10–100 mL (for 35 mm ID) |
| Weight | 2–270 kg (model-dependent) |
| Material Compatibility | Resistant to anhydrous acetonitrile, dichloromethane, pyridine, triethylamine, and other reagents used in phosphoramidite-based solid-phase oligonucleotide synthesis |
| Brand | Cytiva |
|---|---|
| Origin | Sweden |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | OligoPilot |
| Pricing | Available Upon Request |
| Brand | Sepure Instruments |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | OEM Manufacturer |
| Instrument Type | Low-Throughput Synthesizer |
| Coupling Efficiency | DNA >99% |
| Oligonucleotide Length Range | 5–80 bases |
| Synthesis Scale | 50 µmol – 9 mmol |
| UV Detector Wavelength Range | 200–800 nm (4-channel simultaneous detection) |
| Max Operating Pressure | 2 MPa |
| Pump Type | High-Precision Dual Plunger Pumps |
| Flow Rate | ≤ 2 × 100 mL/min |
| Column Reactor Count | 7 |
| Standard Monomer Inlets | 12 |
| Waste Outlets | 8 |
| System Protection | Inert Gas (N₂/Ar) Purge |
| Power Supply | 220 VAC / 600 W |
| Dimensions (W×H×D) | 583 × 614 × 523 mm |
| Included Accessories | PEEK/PTFE Tubing Kit, Installation Manual, User Manual, Fittings, Basic Tool Set |
| Brand | TSIKER |
|---|---|
| Origin | Beijing, China |
| Manufacturer | TSIKER Biotech Co., Ltd. |
| Model | Syn-AJY-5L |
| Pressure Rating | 550 kPa (safety limit) with triple safety protection |
| Max Operating Pressure | 600 kPa (auto rapid vent) |
| Temperature Control Range | Ambient to 90 °C |
| Throughput | Dual 96-well plates (192 oligonucleotide strands per run) |
| Deprotection Efficiency | ≥99% under standard 90 °C / 2 h protocol |
| Dimensions | 600 × 400 × 400 mm (L×W×H) |
| Weight | 40 kg |
| Safety Features | Electronic overpressure alarm, automatic gas cutoff, mechanical pressure relief valve |
| End-of-cycle Alert | Audible tone |
| Brand | TSIKER |
|---|---|
| Origin | Beijing, China |
| Manufacturer | Yes |
| Type | Domestic |
| Model | Syn-CHY-192 |
| Pricing | Upon Request |
| Brand | TSIKER |
|---|---|
| Origin | Beijing, China |
| Manufacturer | Tsingke Biotech Co., Ltd. |
| Type | Low-throughput synthesizer |
| Coupling Efficiency | ≥99% |
| Max. Oligo Length | 200 nt |
| Channels | 12 independent synthesis columns |
| Scale Range | 10 nmol – 100 µmol per column |
| Cycle Time | ≤6 s per coupling step |
| Base Bottle Positions | 10–28 |
| Auxiliary Reagent Positions | 6–9 |
| Dimensions (L×W×H) | 850 × 550 × 1050 mm |
| Weight | 34 kg |