Nanomedicine Production System
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| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Country of Origin | China |
| Model | Custom-Engineered |
| Pricing | Available Upon Technical Specification Review |
| Brand | Aitesen |
|---|---|
| Model | Extru25-20 |
| Max Operating Pressure | 25 MPa |
| Final Particle Size Range | 50–1000 nm |
| Batch Volume Capacity | 0–20 mL |
| Max Liposome Concentration | 200 mg/mL |
| Operating Temperature Range | 5–80 °C |
| Construction Material | SS316L |
| Membrane Diameter | 25 mm |
| Power Source | Compressed Nitrogen Gas |
| Carrier Type | Liposomes |
| Regulatory Compliance | FDA-approved elastomers (O-rings, gaskets), GMP-compatible design |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic |
| Model | MPE-L2 |
| Pricing | Available Upon Request |
| Payload Carrier Type | Lipid Nanoparticle (LNP) |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic |
| Model | MPE-L2 |
| Carrier Type | Liposomes |
| Particle Size Range | <100 nm |
| Polydispersity Index (PDI) | <0.1 |
| Flow Control | Dual-syringe Pump Driven |
| Chip Integration | Modular High-Pressure Microfluidic Chip |
| Process Mode | Continuous On-Line Preparation (OPT) |
| Compliance Framework | Designed for GMP-aligned process development and early-stage validation |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic |
| Model | MPE-L2 |
| Pricing | Available Upon Request |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic |
| Model | MPE-L2 |
| Pricing | Available Upon Request |
| Payload Carrier Type | Lipid Nanoparticle (LNP) |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic |
| Model | MPE-L2 |
| Carrier Type | Lipid Nanoparticles (LNP) |
| Sample Volume Range | Low-volume (µL–mL scale) |
| Particle Size Control Range | Down to <100 nm |
| Polydispersity Index (PDI) | <0.1 |
| Operational Mode | Continuous-flow, multi-injection capable |
| Compliance Framework | Designed for GLP-compliant process development and PAT-integrated workflows |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic |
| Model | MPE-L2 |
| Carrier Type | Liposomes |
| Particle Size Range | <100 nm |
| Polydispersity Index (PDI) | <0.1 |
| Operating Principle | Hydrodynamic Flow-Focusing & High-Pressure Impingement Emulsification |
| Sample Volume per Run | Low-volume (µL–mL scale) |
| In-Process Re-injection Capability | Yes |
| Compliance Context | Designed to support PAT-enabled process development aligned with ICH Q5A, Q5C, and USP <1289> guidelines for nanomedicine characterization |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Product Origin | Domestic (China) |
| Model | MPE-L2 |
| Carrier Type | Lipid Nanoparticle (LNP) |
| Pricing | Available Upon Request |
| Pump-Driven Architecture | Dual-Syringe Precision Injection Pumps |
| Chip-Based Processing | Customizable Microfluidic Chip Platform |
| Minimum Sample Volume | < 100 µL per run |
| Particle Size Range | Down to < 100 nm |
| Polydispersity Index (PDI) | < 0.1 achievable under optimized conditions |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Product Origin | Domestic (China) |
| Model | MPE-Lab Microfluidic Preparation System |
| Flow Rate Reproducibility Error | ≤1% |
| Minimum Working Volume | ≤200 µL |
| Maximum Single-Run Volume | 40 mL |
| Maximum Total Flow Rate | ≥180 mL/min |
| Supported Carriers | Liposomes, Lipid Nanoparticles (LNPs), Polymeric Microparticles, Micelles |
| Compatible Solvent Systems | Miscible and Immiscible Phases |
| Chip Compatibility | Customizable Microfluidic Chips |
| Control Interface | Integrated Touchscreen |
| Software | MPE Lab Microfluidic Control Suite (Lifetime Free Updates) |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Model | MPE-P1 |
| Application | Lipid Nanoparticle (LNP), Liposome, Polymeric Nanoparticle, Emulsion, and Inorganic Nanoparticle Preparation |
| Carrier Type | LNP |
| Regulatory Designation | GMP-Ready Process Development System |
| Control Interface | Integrated Touchscreen with Batch Record & Data Export Capability |
| Scalability | Pilot-Scale Continuous Manufacturing Platform |
| Particle Size Range | Down to <100 nm |
| Polydispersity Index (PDI) | <0.1 |
| Fluid Handling | Dual-Phase Precision Pumping (Phase A + Phase B) |
| Chip-Based Processing | Customizable Microchannel Architecture for Emulsification, Incubation, Size Control, and Secondary Processing |
| Compliance Framework | Engineered for alignment with FDA 21 CFR Part 11, ISO 13485, and ICH Q5A/Q5D principles |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic |
| Model | MPE-P1 |
| Quotation | Upon Request |
| Payload Carrier Type | Lipid Nanoparticles (LNP) |
| Particle Size Range | <100 nm |
| Polydispersity Index (PDI) | <0.1 |
| Flow Control | Dual-Phase Precision Syringe Pumps + High-Pressure Conveying Pump |
| Chip Integration | Customizable Microfluidic Cartridge Architecture |
| Regulatory Alignment | Designed for GMP Process Development per ICH Q5A/Q5B, ISO 13485-aligned engineering controls |
| Data Integrity | Audit-trail-enabled batch records, CSV-compliant data export |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic |
| Model | MPE-P1 |
| Carrier Type | Lipid Nanoparticle (LNP) |
| Pricing | Upon Request |
| Key Features | Integrated touchscreen HMI, batch record logging, exportable process data, high-flow/high-concentration LNP & liposome preparation, PDI < 0.1, particle size down to <100 nm |
| Compliance | Designed for GMP-aligned process development per ICH Q5A/Q5B, ISO 22442, and USP <1043> guidance |
| Software | Embedded control firmware with audit-trail-capable event logging (21 CFR Part 11–ready configuration available) |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic |
| Model | MPE-P1 |
| Carrier Type | Lipid Nanoparticles (LNP) |
| Pricing | Upon Request |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Model | MPE-P1 |
| Carrier Type | Lipid Nanoparticles (LNP) |
| Application Scope | LNP, Liposome, Polymeric Nanoparticles (e.g., PLGA, PEG-PLGA), Emulsions, Inorganic/Organic Nanoparticles (e.g., Gold NPs) |
| Particle Size Range | <100 nm |
| Polydispersity Index (PDI) | <0.1 |
| Flow Control | Dual-channel precision syringe pumps with programmable flow rate ratio and total throughput |
| Chip Interface | Standardized high-pressure microfluidic chip mount (1/4"-28 UNF) |
| Data Logging | Batch-recorded process parameters (flow rates, pressure, temperature, time) with CSV export |
| Compliance Support | Designed for GLP-compliant process development |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic |
| Model | MPE-P1 |
| Carrier Type | Lipid Nanoparticle (LNP) |
| Key Features | Integrated touchscreen interface, batch record logging, data export capability, high-concentration & high-flow-rate LNP/liposome processing, particle size control down to <100 nm, PDI < 0.1 |
| Compliance | Designed for GLP-compliant process development and scalable GMP-aligned manufacturing workflows |
| Brand | ATS |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Direct Manufacturer |
| Region Classification | Domestic (China) |
| Model | AE-o |
| Pricing | Upon Request |
| Carrier Type | Lipid Nanoparticle (LNP) |
| Brand | ATS |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Direct Manufacturer |
| Product Category | Domestic |
| Model | AE001 |
| Price Range | USD 4,200 – 11,200 (FOB) |
| Vesicle Type | Liposomes |
| Sample Volume | 2–800 mL |
| Operating Pressure | 0–1000 psi |
| Final Particle Size | 50–1000 nm |
| Filter Diameter Options | 25 mm / 47 mm / 90 mm |
| Temperature Control Range | 5–80 °C |
| Wetted Materials | 316L Stainless Steel, FDA-Certified Elastomers (O-rings, gaskets), Electropolished Surfaces (Ra ≤ 1.5 µm) |
| Compliance | GMP-Compatible Design, Cleanroom-Ready (ISO Class 5–7) |
| Brand | ATS |
|---|---|
| Origin | Canada |
| Manufacturer | ATS (Producer) |
| Product Type | Imported |
| Model | NF-1 |
| Sample Volume | 0.1–1 mL |
| Membrane Pore Sizes Available | 50, 100, 200, 400, 800, 1000 nm |
| Included Components | 2 × 1000 µL glass syringes, 1 extrusion module, 20 membranes (200 nm & 400 nm standard) |
| Temperature Compatibility | Water-bath compatible (ambient to 60 °C) |
| Residual Volume | ≤1 µL per cycle |
| Weight | <2 kg |
| Optional Upgrades | Mechanical stabilization base, nitrogen-driven pressure control system with adjustable pressure (0.1–6 bar), programmable cycle count and dwell time |
| Brand | ATS |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Direct Manufacturer |
| Product Category | Domestic |
| Model | LF-1 Pneumatic Stand |
| Carrier Type | Liposomes |
| Construction Material | Anodized Aluminum Alloy |
| Actuation Method | Pneumatically Driven Linear Force Application |
| Compatibility | Designed exclusively for ATS LF-1 Liposome Extrusion Devices |
| Brand | ATS |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Direct Manufacturer |
| Product Category | Domestic |
| Model | NANOJ EX5 |
| Price Range | USD 7,000 – 140,000 (FOB) |
| Compatible Vesicle Type | Liposomes |
| Standard Filter Pore Size | 100 nm |
| Optional Pore Sizes | 50, 200, 400, 800 nm |
| Brand | AVESTIN |
|---|---|
| Origin | Canada |
| Model | LF-50 |
| Maximum Sample Volume | 50 mL per run |
| Operating Pressure | Up to 600 psi (41 bar) |
| Membrane Stack Configuration | Up to 3 polycarbonate membranes with support liners |
| Temperature Control | Jacketed stainless steel sample chamber compatible with external thermostatic circulators |
| Compliance | Designed for GMP-compliant processing and cleanability |
| Brand | AVESTIN |
|---|---|
| Origin | Canada |
| Model | LF1 |
| Sample Volume | 0.1–1 mL |
| Membrane Pore Sizes | 50, 100, 200, 400, 800, 1000 nm |
| Operating Principle | Manual pressure-driven extrusion through polycarbonate track-etched membranes |
| Weight | <2 kg |
| Temperature Compatibility | Compatible with water bath (ambient to 60 °C) |
| Includes | Two 1 mL glass syringes, one extrusion module, fifty 100 nm membranes |
| Optional Accessories | Stabilizing base clamp, nitrogen-driven automated extrusion system |
| Brand | Brilliance |
|---|---|
| Origin | Zhejiang, China |
| Manufacturer Type | Direct Manufacturer |
| Product Origin | Domestic (China) |
| Model | Bri-WLK |
| Price Range | USD 7,000 – 70,000 |
| Chip Substrate Materials | PDMS / Borosilicate Glass / 316L Stainless Steel |
| PDMS Chip Dimensions (mm) | 70 × 20 × 2 |
| Glass Chip Dimensions (mm) | 75 × 19 × 2 |
| Microchannel Width (µm) | 30–700 |
| Nozzle Width (µm) | 30–120 |
| Common Nozzle Widths (µm) | 30, 50, 100 |
| Droplet Diameter Range (µm) | 25–300 |
| Droplet Volume Range (nL) | 0.4–10 |
| Brand | Cytiva |
|---|---|
| Origin | Switzerland |
| Model | NanoAssemblr™ Ignite™ Instrument |
| Flow Rate Range | 20–200 mL/min |
| Brand | Dolomite |
|---|---|
| Origin | United Kingdom |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | PLGA Nanoparticle Encapsulation System |
| Carrier Material | Poly(lactic-co-glycolic acid) (PLGA) |
| Encapsulation Method | Continuous-Flow Microfluidics |
| Particle Uniformity (CV) | ≤5% |
| Typical Particle Size Range | 100–500 nm |
| Encapsulation Efficiency | 30–100% |
| Batch-to-Batch Reproducibility | High |
| Compliance Context | Designed for R&D and preclinical GMP-aligned nanomedicine process development |
| Brand | Dolomite |
|---|---|
| Origin | United Kingdom |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | Polymer Nanoparticle Generation System |
| Carrier Type | Polymer |
| Flow Rate Range | 5 nL/min to >100 mL/min |
| Sample Volume Capacity | 0.5 mL to several liters |
| Maximum Operating Pressure | 0–10 bar |
| Brand | Cytiva |
|---|---|
| Origin | Switzerland |
| Model | NanoAssemblr™ Blaze™ System |
| Volume Range | 1 L (Blaze™) / up to 10 L (Blaze+™) |
| System Architecture | Closed, single-use, GMP-ready process development platform |
| Core Technology | NxGen™ microfluidic mixing |
| Regulatory Alignment | Supports FDA 21 CFR Part 11–compliant data integrity, GLP/GMP process transfer readiness |
| Disposable Components | NxGen™ single-use chips (with/without inline dilution), sterile tubing kits for external vessel integration |
| Downstream Compatibility | Integrated TFF, sterile filtration, and fill-finish workflow support |
| Scalability Pathway | Direct CPP/CQA transfer from Blaze™ → Blaze+™ → NanoAssemblr™ Production System |
| Brand | Cytiva |
|---|---|
| Origin | Switzerland |
| Manufacturer Type | Authorized Distributor |
| Product Category | Imported |
| Model | NanoAssemblr™ Commercial Manufacturing System |
| Pricing | Upon Request |
| Flow Rate Range | 6–48 L/h (dependent on disposable flow path kit) |
| Brand | Cytiva |
|---|---|
| Origin | Switzerland |
| Model | NanoAssemblr™ GMP System |
| Flow Rate Range | 60–200 mL/min (3.6–12 L/h) |