Acmer 150F Flow-Mode Peristaltic Pump

Overview

The Acmer 150F Flow-Mode Peristaltic Pump is a precision-engineered laboratory peristaltic pump designed for accurate, pulse-free, and contamination-free fluid transfer in analytical, bioprocessing, and quality control environments. Utilizing the fundamental principle of peristalsis—where rollers compress flexible tubing to displace fluid—the 150F delivers consistent volumetric delivery without internal valves, seals, or wetted metal parts. This architecture eliminates cross-contamination risk and ensures compatibility with aggressive solvents, biological suspensions, cell cultures, and particulate-laden media. Its compact footprint (W × D × H: 220 × 180 × 240 mm) and low-noise brushless DC motor support integration into fume hoods, glove boxes, and automated liquid handling platforms. The pump meets essential mechanical reliability standards for continuous operation under GLP-compliant workflows and is routinely deployed in applications requiring traceable, repeatable dosing across pharmaceutical development, environmental sample preparation, and academic research labs.

Key Features

• High-resolution 3.0-inch HD TFT touchscreen with intuitive icon-based navigation and real-time parameter feedback—including instantaneous flow rate (mL/min), rotational speed (rpm), elapsed time, and dispensed volume.
• Three operational modes: Flow Mode (direct setpoint entry for flow or rpm), Timer Mode (programmable run duration with auto-stop), and Volume Mode (precise delivery of user-defined volumes with automatic termination).
• Multi-tubing calibration protocol supporting up to five tubing size configurations (ID 1.6–6.4 mm); enables correction of non-linear flow response across the full dynamic range.
• In-run parameter adjustment: Operators may modify flow rate or speed during active pumping without interrupting fluid continuity—critical for gradient elution, titration, or adaptive sampling protocols.
• RS-485 serial interface compliant with Modbus RTU protocol for bidirectional communication with PLCs, SCADA systems, or LIMS; supports remote start/stop, speed ramping, and status polling.
• Dedicated analog input (0–5 V or 4–20 mA) and digital I/O terminals for external trigger synchronization, enabling seamless integration into multi-instrument workflows.

Sample Compatibility & Compliance

The 150F accommodates a broad spectrum of fluid types—including aqueous buffers, organic solvents (e.g., acetonitrile, isopropanol), viscous polymer solutions (up to 5,000 mPa·s), and shear-sensitive biological samples—by virtue of its tubing-isolated fluid path. Compatible tubing materials include platinum-cured silicone (for general use), Tygon® E-3603 (for ozone and UV resistance), and PharMed® BPT (USP Class VI and FDA-compliant for pharmaceutical contact). Pump head options—F154, F156, and TH15—are engineered for optimal occlusion consistency and roller alignment, ensuring long-term flow stability (< ±1.5% RSD over 8 hours per ASTM D7281). While not certified to IEC 61000-6-2/4 or UL 61010-1 out-of-the-box, the device complies with CE marking requirements for electromagnetic compatibility and low-voltage safety when operated within specified ambient conditions (10–40 °C, <80% RH non-condensing).

Software & Data Management

The 150F operates as a standalone instrument but supports audit-ready data capture via optional PC software (Acmer PumpLink v2.1). This application logs timestamped operational records—including mode selection, setpoints, actual flow deviations, calibration events, and error codes—with export to CSV or PDF. All configuration changes are stored with user ID and system timestamp, satisfying basic ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate) for regulated environments. Though not natively 21 CFR Part 11 compliant, the firmware architecture allows integration with validated third-party electronic lab notebooks (ELNs) or chromatography data systems (CDS) that enforce electronic signature and role-based access controls.

Applications

• Automated reagent dispensing in ELISA and PCR setup workflows.
• Continuous feed of mobile phase or standards in HPLC and IC systems.
• Controlled nutrient or acid/base addition in bioreactor pH and DO control loops.
• Low-flow sampling in online water quality monitoring stations (e.g., nitrate, phosphate analyzers).
• Calibration standard delivery in gravimetric and spectrophotometric validation procedures per ISO/IEC 17025.
• Microfluidic chip priming and perfusion in organ-on-chip platforms.

FAQ

What tubing sizes are supported—and how do they affect flow accuracy?
The 150F supports inner diameters from 1.6 mm (13#) to 6.4 mm (25#). Smaller IDs yield higher resolution at low flows (e.g., 0.0013 mL/min with 13#), while larger IDs enable high-volume throughput (up to 260 mL/min with TH15 and 25# tubing). Accuracy is optimized through tubing-specific calibration routines.
Can the pump be integrated into a GMP manufacturing environment?
Yes—when paired with USP Class VI tubing and operated under documented calibration and maintenance schedules, the 150F supports GMP-aligned processes. Full 21 CFR Part 11 compliance requires integration with a validated host system.
Is firmware upgrade capability available?
Yes. Firmware updates are delivered via micro-USB and preserve all user-configured parameters and calibration coefficients.
What is the maximum allowable backpressure?
The pump is rated for continuous operation at ≤200 kPa (2 bar) with standard silicone tubing; performance degrades above this threshold due to tubing rebound limitations.
Does the pump support programmable ramping or multi-step profiles?
Not natively—but complex sequences can be executed via RS-485 commands issued from an external controller using Modbus function codes 06 (preset single register) and 16 (preset multiple registers).