ADVANTEC CCP-10-E1D Polypropylene Melt-Blown Depth Filter Cartridge
| Brand | ADVANTEC (TAMASAKI, Kyoto, Japan) |
|---|---|
| Origin | Japan |
| Model | CCP-10-E1D |
| Nominal Pore Size | 10 µm |
| Effective Filtration Area | 550 cm² |
| Max Operating Pressure | 0.39 MPa @ 25°C |
| Max Operating Temperature | 60°C |
| Construction Material | Polypropylene (Melt-Blown) |
| Dimensions | Ø77 mm × 102 mm (L) |
| Inlet/Outlet | 1/4" NPT Male |
| Packaging | 85 × 85 × 130 mm, 180 g |
Overview
The ADVANTEC CCP-10-E1D is a high-performance, melt-blown polypropylene depth filter cartridge engineered for reliable particulate removal in critical laboratory, pharmaceutical, and industrial fluid processing applications. Designed using proprietary thermally bonded polypropylene microfibers, this cartridge operates on the principle of depth filtration—where contaminants are captured throughout the three-dimensional fiber matrix rather than solely at the surface. This architecture provides superior dirt-holding capacity, extended service life, and consistent flow performance under variable challenge loads. Its nominal pore rating of 10 µm ensures efficient retention of suspended solids—including rust, scale, polymer agglomerates, and process-generated particulates—while maintaining low differential pressure buildup across a wide range of aqueous and chemically aggressive streams.
Key Features
- Melt-blown polypropylene construction with narrow fiber diameter distribution and high void volume (>80%), enabling high contaminant loading capacity and prolonged operational cycle life.
- Chemical resistance validated across broad pH range (pH 1–14) and compatibility with common organic solvents (e.g., alcohols, acetone, hydrocarbons), dilute acids (HCl, HNO₃), and alkalis (NaOH).
- No binder or surfactant additives—minimizing extractables and ensuring compliance with USP and ISO 10993-12 for non-cytotoxic, non-leachable filtration components.
- Robust mechanical integrity: rated for continuous operation up to 0.39 MPa at 25°C and short-term exposure to 60°C, suitable for ambient and mildly elevated temperature processes.
- Standardized 1/4″ NPT male end caps facilitate direct integration into modular filter housings compliant with ASME B16.5 Class 150 flange interfaces or threaded SAE J514 adapters.
Sample Compatibility & Compliance
The CCP-10-E1D demonstrates proven compatibility with purified water (PW), water for injection (WFI) pre-filtration, buffer solutions, cell culture media, solvent-based cleaning agents, and low-viscosity process intermediates. It is routinely deployed upstream of membrane filters (e.g., 0.45 µm or 0.22 µm PVDF/PES) to protect final sterilizing-grade membranes from premature clogging. The cartridge meets ISO 9001-certified manufacturing controls and conforms to JIS Z 8801-1 for particle retention testing methodology. While not individually certified to FDA 21 CFR Part 11, its material traceability, lot-specific CoA documentation, and extractables profile support qualification under GMP/GLP environments when installed in validated filtration trains.
Software & Data Management
As a passive mechanical filtration component, the CCP-10-E1D does not incorporate embedded electronics or digital connectivity. However, it integrates seamlessly into automated filtration systems equipped with pressure transducers, flow meters, and SCADA/HMI platforms. Differential pressure monitoring across the cartridge enables predictive maintenance scheduling—typical end-of-life thresholds are defined as ΔP ≥ 0.2 MPa at rated flow rate. Batch records, replacement logs, and integrity test data (e.g., forward flow or bubble point) can be archived within LIMS or MES platforms per Annex 11 requirements. ADVANTEC provides full material declarations (IMDS-compliant), RoHS/REACH statements, and extractables testing reports upon request for regulatory submissions.
Applications
- Prefiltration of liquid chromatography mobile phases and sample preparation solvents in analytical labs.
- Clarification of fermentation broths and harvest streams prior to ultrafiltration or chromatography in bioprocessing.
- Particulate control in clean steam condensate return loops and HVAC humidification systems.
- Protection of high-value downstream components including diaphragm pumps, precision nozzles, and optical sensors in semiconductor wet benches.
- Final polishing of cosmetics and personal care formulations where color stability and clarity are critical quality attributes.
FAQ
Is the CCP-10-E1D suitable for sterile filtration?
No—this is a prefilter rated at 10 µm nominal retention and is not intended for microbial removal. It must be used upstream of a 0.22 µm sterilizing-grade membrane filter.
Can it be autoclaved?
No—polypropylene melt-blown cartridges are not designed for repeated steam sterilization. Maximum continuous exposure is 60°C; autoclaving (121°C) will cause irreversible structural collapse.
What is the recommended maximum flow rate?
Flow rate depends on system pressure drop, viscosity, and particle load. At 0.39 MPa inlet pressure and 25°C, typical maximum flux is 12–15 L/min for water-like fluids; consult ADVANTEC’s application engineering team for process-specific sizing.
Does it comply with USP Class VI biological reactivity standards?
While the base polypropylene resin meets USP and cytotoxicity requirements, full USP Class VI certification requires device-level testing. ADVANTEC supplies material-level biocompatibility data supporting qualification under ISO 10993-5/-10 frameworks.
Are replacement cartridges supplied with lot-specific certificates of analysis?
Yes—each production lot includes a CoA documenting dimensional verification, weight, differential pressure baseline, and extractables screening results, traceable to JIS Z 3101 calibration standards.
