Agilent Certified Refurbished 6410 Triple Quadrupole LC/MS System
| Brand | Agilent Technologies |
|---|---|
| Origin | Singapore |
| Manufacturer | Agilent Technologies |
| Origin Category | Imported |
| Model | 6410 |
| Product Type | Mass Spectrometer |
| Warranty | 1 Year |
| Certification | Agilent Certified Refurbished Program |
Overview
The Agilent Certified Refurbished 6410 Triple Quadrupole LC/MS System is a high-performance, robust liquid chromatography–mass spectrometry platform engineered for precise quantitative analysis in regulated and research environments. Based on Agilent’s proven triple quadrupole architecture, the system operates via electrospray ionization (ESI) or atmospheric pressure chemical ionization (APCI), enabling selective reaction monitoring (SRM) with exceptional specificity and linear dynamic range. The 6410 integrates seamlessly with Agilent 1200 Series HPLC systems and delivers reproducible quantitation across complex matrices—including biological fluids, environmental extracts, and pharmaceutical formulations—without compromising data integrity or method transferability. As a certified refurbished unit, it undergoes Agilent’s standardized refurbishment protocol aligned with original factory specifications, ensuring compliance with ISO/IEC 17025 traceability requirements for instrument qualification.
Key Features
- Factory-certified refurbishment performed exclusively by Agilent-authorized service engineers in Singapore
- Full replacement of consumable components—including ion source parts, detector assemblies, vacuum pumps, and electronics modules—with genuine Agilent OEM parts
- Comprehensive operational verification: system suitability testing per Agilent Application Note 5991-3539EN, including mass accuracy (< ±0.2 Da), SRM sensitivity (≤5 fg on-column caffeine), and retention time stability (RSD < 0.3% over 24 h)
- Complete mechanical and cosmetic renewal: new front panel, updated firmware (vB.07.00 or later), and re-calibrated vacuum manifold assembly
- Inclusion of essential startup accessories: ESI/APCI source kits, calibration standards (tuning mix), and system validation report documenting pre- and post-refurbishment performance metrics
- One-year limited warranty covering parts, labor, and remote diagnostics—identical in scope to Agilent’s new-instrument warranty
Sample Compatibility & Compliance
The 6410 supports broad sample compatibility across small-molecule applications, including residual solvent analysis, impurity profiling, pharmacokinetic (PK) bioanalysis, and environmental contaminant screening. Its ion optics and collision cell design minimize matrix suppression effects while maintaining >95% signal recovery in plasma and urine extracts following protein precipitation or solid-phase extraction. The system meets critical regulatory expectations for analytical instrument qualification (AIQ) under USP , ASTM E2500-13, and ICH Q2(R2). When operated with Agilent OpenLab CDS software and configured with audit trail, electronic signatures, and user access controls, it satisfies FDA 21 CFR Part 11 and EU Annex 11 requirements for data governance in GLP and GMP laboratories.
Software & Data Management
The refurbished 6410 ships with Agilent MassHunter Workstation Software (Quantitative Analysis B.08.00 or higher), supporting automated method development, batch processing, and customizable report generation. All data files are stored in vendor-native .d format, fully compatible with Agilent’s enterprise-scale data management solutions—including OpenLab ECM and MassHunter Quant Database. Audit trail functionality records all parameter changes, acquisition events, and processing actions with timestamps and operator IDs. Optional integration with Agilent’s Intelligent Reporting Engine enables real-time QC charting (e.g., control charts, trend analysis) directly within the acquisition interface, facilitating continuous process verification per ICH Q5E principles.
Applications
- Regulatory bioanalysis: validated PK/PD studies compliant with FDA Bioanalytical Method Validation Guidance (2018)
- Food safety testing: multi-residue pesticide screening in fruits, vegetables, and dairy per EU SANTE/11312/2021 guidelines
- Environmental monitoring: quantification of PFAS, PAHs, and endocrine disruptors in water and soil extracts at sub-ppt levels
- Pharmaceutical quality control: assay of active pharmaceutical ingredients (APIs), degradation products, and genotoxic impurities per ICH Q3A–Q3D
- Clinical toxicology: confirmation and quantitation of drugs of abuse, opioids, and novel psychoactive substances in forensic specimens
FAQ
What documentation accompanies the certified refurbished 6410 system?
A complete Certificate of Refurbishment, System Validation Report (including pre- and post-refurbishment performance data), and Agilent’s Standard Terms and Conditions for Refurbished Equipment are provided.
Can this system be integrated into an existing Agilent OpenLab CDS environment?
Yes—the 6410 is fully interoperable with OpenLab CDS v2.4 or later and supports centralized user management, method synchronization, and electronic record archiving.
Is installation and training included?
Installation and operator training are optional value-added services available through Agilent’s Global Field Service organization; pricing and scheduling are coordinated post-purchase.
Does the 1-year warranty cover preventive maintenance?
The warranty covers repair or replacement of defective parts and associated labor but does not include scheduled preventive maintenance visits; those are available under separate support contracts.
Are spare parts and consumables still available for the 6410 platform?
Yes—Agilent maintains full parts availability for the 6410 through its global logistics network, with typical lead times of ≤5 business days for critical components such as ion sources and detector assemblies.
