ALISN THA-1000 Temperature and Humidity Controlled Environmental Chamber

Overview

The ALISN THA-1000 is a high-stability upright environmental test chamber engineered for precise, long-term temperature and humidity control in regulated laboratory and industrial quality assurance environments. It operates on the principle of closed-loop feedback regulation using dual-sensor monitoring (HERAEUS platinum resistance thermometers and E+E capacitive relative humidity sensors) coupled with inverter-driven refrigeration and PID-fuzzy hybrid control logic. Designed to meet the stringent repeatability and traceability requirements of pharmaceutical stability testing (ICH Q1–Q5), food shelf-life validation, polymer aging studies, and material conditioning per ASTM D618 and ISO 291, the THA-1000 delivers calibrated environmental profiles across its full operational envelope (−10 °C to 85 °C; 10–98 % RH) under continuous load conditions.

Key Features

• Inverter-controlled SECOP (Danfoss) hermetic compressor and EBM axial condenser fan—enabling frost-free operation, reduced power consumption (up to 40 % lower than conventional units), and rapid recovery (<15 min) after door opening
• Monolithic polyurethane insulation (≥120 mm thickness) applied via one-shot foaming process—ensuring structural rigidity, thermal homogeneity, and minimized heat leakage
• 7-inch resistive touchscreen interface with intuitive icon-based navigation, real-time dual-parameter curve plotting, and multi-segment programmable profiles (up to 99 cycles, 24 steps per cycle)
• Immutable data integrity architecture: All sensor readings, setpoint changes, alarms, and user actions are time-stamped and stored internally with SHA-256 hashing; exportable only via encrypted U-disk in CSV format—no post-acquisition editing permitted
• Comprehensive safety suite: Over-temperature cutoff, refrigerant high-pressure protection, low-humidity dry-run prevention, water-level monitoring, door-open alert, and ground-fault circuit interruption
• Multi-point temperature offset calibration (up to 12 points)—compensating for spatial gradients without hardware modification
• Dual-glass observation door with tempered inner pane and silicone-sealed 50 mm access port—supporting external probe feedthrough and non-invasive monitoring

Sample Compatibility & Compliance

The THA-1000 accommodates diverse sample geometries and mass loads within its 1012 L stainless-steel interior (304-grade, electropolished finish). Its uniformity performance (±0.5 °C/±1.5 % RH across working volume at 25 °C/60 % RH, empty chamber) complies with ISO 16770:2021 for environmental chamber qualification. The system supports GLP/GMP-aligned workflows through built-in audit trail (16,000+ entries), role-based access control (administrator + four configurable users), and electronic signature-ready event logging. Optional IQ/OQ documentation packages are available for FDA 21 CFR Part 11 compliance validation. Calibration certificates traceable to NIM (China National Institute of Metrology) or UKAS-accredited labs may be provided upon request.

Software & Data Management

No proprietary software installation is required: raw data export occurs exclusively via FAT32-formatted USB drives in plain-text CSV with ISO 8601 timestamps and SI-unit headers. The embedded controller logs all parameters at user-selectable intervals (1 s to 60 min), including chamber setpoints, actual readings, compressor duty cycle, heater status, and alarm codes. Historical trend analysis is performed directly on the touchscreen—supporting overlay comparison of up to three datasets, zoom/pan functionality, and screenshot capture. RS-232/RS-485 interfaces enable integration into centralized SCADA or LIMS platforms using Modbus RTU protocol; no third-party drivers or middleware are needed.

Applications

• Pharmaceutical stability studies (long-term, accelerated, intermediate conditions per ICH guidelines)
• Food product shelf-life determination under controlled moisture migration conditions
• Polymer hygrothermal aging per ASTM D570 and ISO 62
• Electronics component preconditioning prior to thermal shock or HALT testing
• Biological reagent storage validation and humidity-sensitive reference material conditioning
• Calibration laboratory ambient environment control for precision weighing and dimensional metrology

FAQ

Is the THA-1000 compliant with FDA 21 CFR Part 11 for electronic records?
Yes—the system implements audit trail, electronic signatures (via password-authenticated user roles), and data immutability features aligned with Part 11 Subpart B requirements. Full validation support documentation is available.
Can the chamber operate continuously at 85 °C and 98 % RH?
Yes—its reinforced insulation, oversized condenser, and adaptive inverter control allow uninterrupted operation across the full specified range, verified per ISO 16770 Annex C.
What is the maximum allowable sample mass without compromising uniformity?
For optimal performance, total sample volume should not exceed 30 % of internal chamber volume (≤300 L); thermal mass must be pre-equilibrated to minimize transient load effects.
Does the unit support remote monitoring via Ethernet or Wi-Fi?
No native Ethernet/Wi-Fi module is included; however, RS-485 Modbus output enables connection to industrial gateways for cloud-based telemetry when integrated into existing facility networks.
Are calibration certificates included with shipment?
A factory-as-built verification report (including temperature/humidity uniformity at three standard setpoints) is supplied. NIST-traceable calibration certificates require separate ordering and on-site or return-to-factory service.