Allsheng KD200 Visual Nitrogen Evaporator

Overview

The Allsheng KD200 Visual Nitrogen Evaporator is an engineered dry-block thermal concentrator designed for high-throughput, oxygen-sensitive sample preparation in analytical chemistry, pharmaceutical development, and clinical research laboratories. It operates on the principle of inert gas-assisted solvent evaporation: nitrogen gas—delivered via individually adjustable stainless-steel needles—is directed tangentially across the surface of heated samples, accelerating solvent removal while minimizing oxidative degradation and analyte loss. Unlike rotary evaporation, which processes one or few samples sequentially under vacuum, the KD200 enables parallel concentration of up to 12 samples under ambient pressure, significantly reducing turnaround time in LC-MS, GC-MS, ELISA, steroid hormone profiling, and drug metabolism studies. Its transparent front panel and vertically adjustable gas manifold allow real-time visual monitoring of solvent meniscus recession—a critical advantage when optimizing recovery of thermolabile or low-concentration analytes.

Key Features

• Dry-block heating system with PTFE-coated aluminum block ensures uniform thermal distribution and rapid heat-up (≤30 minutes from 40°C to 150°C)
• High-resolution digital PID controller with 0.1°C display resolution and programmable setpoint stability (±1.0°C at 40–50°C; ±1.5°C at 100–150°C)
• 12 independently controllable gas delivery channels, each equipped with a precision needle valve for optimized flow per tube—eliminating cross-contamination and nitrogen waste
• Vertically and laterally adjustable gas manifold accommodates tube diameters from 10 mm to 20 mm (Φ10–Φ20 mm), supported by interchangeable modular blocks (BD01–BD07)
• Integrated safety architecture: over-temperature cut-off, self-diagnostic fault reporting, audible/visual alarm, and automatic shutdown upon thermal excursion
• Real-time dual-display interface showing current temperature and remaining countdown time (1 min – 99 h 59 min)
• Compact footprint (280 × 240 × 500 mm) and rear-mounted gas inlet enable seamless integration into fume hoods during toxic solvent evaporation (e.g., chloroform, hexane, ethyl acetate)

Sample Compatibility & Compliance

The KD200 accepts standard 10–20 mL glass or polypropylene tubes—including conical-bottom centrifuge tubes and culture tubes—with optional adapter blocks ensuring secure positioning and consistent needle-to-surface distance. Its design supports routine use in regulated environments: temperature logs are manually recordable for GLP documentation, and the instrument’s deterministic thermal response aligns with ISO 17025 clause 6.4.3 (equipment suitability) and USP guidance on analytical instrument qualification. While not inherently 21 CFR Part 11 compliant (lacking electronic audit trail), it serves as a validated component within broader Part 11–compliant workflows when paired with external data capture systems.

Software & Data Management

The KD200 operates via embedded firmware without proprietary software dependency—ensuring long-term operational continuity and minimizing IT validation burden. All parameters (set temperature, timer duration, and real-time readings) are retained in non-volatile memory during power interruption. For laboratories requiring electronic records, the device supports integration with LIMS or ELN platforms via external USB data loggers or RS-232 interfaces (optional accessory). Temperature calibration certificates (traceable to NIST standards) are available upon request for IQ/OQ documentation packages.

Applications

• Routine concentration of extracts prior to LC-MS/MS analysis in bioanalytical labs (e.g., plasma, urine, tissue homogenates)
• Preparative cleanup in pesticide residue testing (AOAC 2007.01, EN 15662)
• Hormone quantification workflows requiring minimal derivatization (cortisol, testosterone, estradiol)
• High-throughput sample prep for forensic toxicology screening panels
• Stability-indicating method development where thermal history must be controlled and documented
• Environmental analysis of PAHs, PCBs, and organochlorine pesticides in soil/water extracts

FAQ

Is the KD200 suitable for use with flammable solvents?
Yes—when operated inside a certified fume hood with appropriate nitrogen supply pressure regulation (typically 10–30 psi), it safely handles ethanol, methanol, acetone, and ethyl acetate. Never exceed manufacturer-specified gas inlet pressure.
Can I calibrate the temperature sensor myself?
The unit includes a reference port for external PT100 probe verification. Full calibration requires factory service or third-party accredited lab per ISO/IEC 17025; field checks using traceable reference thermometers are recommended quarterly.
What maintenance is required?
Monthly inspection of needle tips for clogging, annual cleaning of heating block grooves with isopropyl alcohol, and biannual verification of gas line integrity and valve responsiveness.
Does it support external timer triggering or remote start?
No native Ethernet or digital I/O; however, the power input can be controlled via programmable relay modules integrated into building automation or lab-wide scheduling systems.
Are replacement modules available for non-standard tube formats?
Custom adapter plates (e.g., for 24-well plates or microcentrifuge tubes) can be fabricated upon engineering review—contact Allsheng Technical Support with dimensional specifications and thermal load requirements.