ANAYN CYNS-16K 7-inch Touchscreen Vacuum Parallel Evaporator with Uniform Water Bath Heating

Overview

The ANAYN CYNS-16K is a high-throughput vacuum parallel evaporator engineered for reproducible, scalable sample concentration under controlled reduced-pressure conditions. It operates on the principle of simultaneous solvent evaporation via vacuum-assisted boiling point depression combined with uniform water bath heating—enabling efficient removal of volatile and moderately high-boiling solvents (e.g., methanol, acetonitrile, ethyl acetate, dichloromethane) without thermal degradation of thermolabile analytes. Unlike single-vessel rotary evaporators or nitrogen blow-down systems, the CYNS-16K processes up to 16 samples in parallel while maintaining strict inter-sample temperature uniformity (±1 °C across all positions), critical for comparative quantitative analysis in regulated environments. Its sealed, modular architecture minimizes cross-contamination risk and supports method transfer across QC laboratories in food safety, environmental testing, pharmaceutical development, and natural product research.

Key Features

• Uniform water bath heating system (ambient to 100 °C) with non-contact thermal transfer—eliminates hot spots and ensures identical thermal exposure across all 16 sample positions
• Independent sealing and venting per sample channel, preventing bumping, foaming-induced cross-contamination, and backflow during vacuum cycling
• Dual-stage condensation module comprising a primary coiled condenser and secondary cold trap, integrated with a recirculating chiller for >95% solvent recovery efficiency
• 7-inch industrial-grade capacitive touchscreen interface supporting intuitive parameter programming—including temperature ramping, vacuum step control, timer (0–999 min), and real-time status monitoring
• Triple-transparent borosilicate chamber (≥8 L internal volume) with unobstructed bottom-view access—enables direct visual assessment of endpoint detection (e.g., meniscus stabilization, crystallization onset)
• PFA-coated sealing lid and threaded glass sample tubes ensure chemical inertness against aggressive solvents and acidic/basic matrices
• Integrated low-level water alarm with red LED indicator and on-screen alert—prevents dry-heating damage to the bath and maintains thermal stability
• PTFE-diaphragm vacuum pump (20–30 L/min flow, ≤8 mbar ultimate vacuum) with solvent-buffered inlet and acoustic dampening (<60 dB(A)) for quiet operation in shared lab spaces
• Chemically resistant fluid path constructed from PEEK, PTFE, and borosilicate glass—validated for compatibility with USP Class VI solvents and EPA Method 500/600 series applications

Sample Compatibility & Compliance

The CYNS-16K accommodates standard 150 mL and 200 mL round-bottom or flat-bottom glass vials with interchangeable height-adjustable sample racks. Its modular design allows seamless integration into existing sample preparation workflows compliant with ASTM D5291 (petroleum distillates), ISO 11843-3 (detection limits), and EPA SW-846 Methods 3510C (liquid-liquid extraction) and 3550C (solid-phase extraction eluate concentration). All wetted surfaces meet USP extractables profiling standards. The instrument’s sealed vacuum path and solvent recovery system support adherence to OSHA 29 CFR 1910.1200 (HCS) and EU REACH Annex XVII requirements for VOC containment. Audit-ready operation logs—including time-stamped temperature/vacuum setpoints, run duration, and alarm events—are exportable via USB for GLP/GMP documentation.

Software & Data Management

While the CYNS-16K operates as a standalone benchtop unit without proprietary PC software, its embedded firmware stores up to 100 user-defined methods with full parameter recall (temperature profile, vacuum sequence, timer, agitation if equipped). All operational data—including start/stop timestamps, active alarms, and real-time sensor readings—are retained in non-volatile memory and exportable as CSV files via USB-A port. The interface supports multilingual display (English, Spanish, French, German) and complies with FDA 21 CFR Part 11 principles through password-protected method editing, electronic signature prompts for critical parameter changes, and immutable audit trails accessible only by administrator credentials.

Applications

• Environmental analysis: Concentration of pesticide residues (e.g., organophosphates, pyrethroids) from QuEChERS extracts prior to GC-MS/MS analysis
• Food & beverage testing: Removal of acetonitrile from AOAC 2007.01 extracts of fruits, vegetables, and dairy products
• Pharmaceutical R&D: Solvent exchange and residual solvent reduction in API purification steps per ICH Q3C guidelines
• Natural product isolation: Parallel concentration of fractionated plant extracts post-column chromatography (e.g., flash, MPLC)
• Clinical toxicology: High-throughput cleanup of urine/blood samples prior to LC-MS quantification of drugs of abuse
• Materials science: Solvent removal from nanoparticle dispersions and polymer solution casting protocols

FAQ

What types of solvents can be safely concentrated using the CYNS-16K?
The system is validated for common organic solvents including methanol, ethanol, acetonitrile, acetone, ethyl acetate, dichloromethane, and hexane. Chlorinated and highly corrosive solvents (e.g., concentrated HCl, HF) require optional quartz or Hastelloy components and are not supported with standard configuration.
Is the instrument compatible with regulatory audit requirements such as GLP or ISO 17025?
Yes—the device provides traceable operational records, password-controlled method access, and physical safeguards (e.g., sealed vacuum path, solvent recovery) aligned with ISO/IEC 17025:2017 Clause 7.7 and OECD GLP Principles Section 5.2.1.
Can the CYNS-16K be integrated with automated liquid handlers or LIMS?
It does not feature Ethernet or RS-232 connectivity natively; however, external PLC-based triggers via dry-contact I/O (optional add-on) enable synchronization with robotic sample introduction platforms.
What maintenance intervals are recommended for sustained performance?
Vacuum pump oil replacement every 500 hours; PTFE diaphragm inspection every 1,000 hours; condenser coil cleaning with isopropanol every 200 runs; water bath deionized water refresh every 48 operating hours.
Does the unit include a vacuum pump and chiller?
Yes—each CYNS-16K shipment includes a built-in PTFE-diaphragm vacuum pump and a dedicated recirculating chiller unit rated for −10 °C to +25 °C output, pre-calibrated and factory-tested.