ANJIE AJ-600 Automated Liquid Dispensing System

Overview

The ANJIE AJ-600 Automated Liquid Dispensing System is an integrated laboratory workstation engineered for precise, repeatable, and traceable preparation of standardized liquid solutions in analytical, quality control, and method development environments. It operates on a gravimetric and volumetric hybrid dispensing principle—leveraging calibrated peristaltic or piston-driven fluid handling modules, real-time weight feedback (when interfaced with external analytical balances), and closed-loop temperature regulation to ensure compositional fidelity across batch preparations. Designed for compliance-sensitive workflows, the AJ-600 supports unattended operation for multi-step dilution, spiking, standard addition, and buffer formulation tasks—reducing manual intervention, minimizing operator-induced variability, and strengthening data integrity in GLP- and GMP-aligned laboratories.

Key Features

• Full-color capacitive touchscreen interface with context-aware navigation and multilingual support (English default), enabling rapid method selection, parameter adjustment, and real-time status monitoring.
• Integrated temperature-controlled sample chamber with Peltier-based heating/cooling, maintaining setpoints from 4 °C to 60 °C at ±1 °C stability—critical for thermally sensitive analytes, enzyme substrates, or volatile organic standards.
• Automated magnetic or overhead stirring mechanism synchronized with dispensing events to ensure homogeneity prior to final volume verification or transfer.
• Self-purging headspace liquid-path architecture: eliminates manual priming or air-bubble management by automatically evacuating residual gas from tubing and manifolds between runs using programmable vacuum and positive-pressure cycles.
• Onboard cleaning protocol suite—including solvent flush, water rinse, and dry-purge sequences—triggered automatically post-run or scheduled via calendar-based maintenance timers.
• Embedded method library supporting ≥10 user-configurable protocols; each stores volume targets, temperature setpoints, stir duration, cleaning steps, and metadata tags for version control and reusability.
• Comprehensive electronic log system compliant with ALCOA+ principles: timestamps all user logins, method executions, parameter edits, error alerts, and cleaning cycles—with immutable storage and export capability (CSV/Excel) for internal audit or regulatory review.

Sample Compatibility & Compliance

The AJ-600 accommodates aqueous, organic, and mixed-solvent systems within ISO Class 5–7 cleanroom-compatible enclosures (optional). Fluid contact materials include chemically resistant PTFE, PEEK, and borosilicate glass—validated for compatibility with HPLC-grade solvents, dilute acids/bases, and common pharmaceutical excipients. The system meets general requirements for ISO/IEC 17025:2017 clause 5.9 (method validation), supports traceability per ASTM E2500-13 (good practice for equipment qualification), and provides configurable audit trails aligned with FDA 21 CFR Part 11 Subpart B (electronic records and signatures) when deployed with validated IT infrastructure and access controls.

Software & Data Management

AJ-600 firmware includes embedded Linux-based control software with local storage (≥8 GB flash memory) and USB 3.0/RS-232/Ethernet connectivity options. Method files and logs are exportable without proprietary software dependencies. Optional PC-based companion software (AJ-Control Suite v2.x) enables remote scheduling, centralized fleet management, SOP-linked workflow enforcement, and integration with LIMS via HL7 or RESTful API. All data exports retain native timestamps, user IDs, instrument serial numbers, and digital signatures where enabled—facilitating direct ingestion into ELN platforms or statistical process control dashboards.

Applications

• Preparation of certified reference material (CRM) dilutions for ICP-MS, AAS, and IC calibration curves.
• Automated spike recovery studies in environmental testing labs (e.g., EPA Method 200.8, ISO 17294-2).
• Formulation of mobile phase blends and gradient eluents in HPLC/UHPLC method development.
• Reconstitution and serial dilution of biologics standards under cold-chain conditions (4 °C hold mode).
• QC batch release testing for pharmaceutical intermediates requiring strict volumetric consistency (USP <1251>).
• High-throughput sample spiking for food safety labs performing mycotoxin or pesticide residue analysis (AOAC 2012.01, EN 15662).

FAQ

Does the AJ-600 support integration with third-party balances or autosamplers?
Yes—via RS-232 or Ethernet, the system accepts real-time mass input from METTLER TOLEDO, Sartorius, and Shimadzu analytical balances, and can trigger external autosampler tray advancement using TTL or relay outputs.
Is validation documentation provided for IQ/OQ/PQ protocols?
ANJIE supplies a vendor-qualified User Requirement Specification (URS) template and factory-tested OQ checklists; site-specific PQ must be performed by the end user per ISO/IEC 17025 or internal SOPs.
Can dispensing accuracy be verified independently?
Yes—the system includes a built-in gravimetric verification mode that prompts sequential dispense-and-weigh cycles using an external balance, generating deviation reports against target volumes.
What maintenance intervals are recommended?
Daily: visual inspection of tubing and seals; weekly: headspace purge cycle validation; quarterly: pump tubing replacement and temperature sensor calibration using NIST-traceable references.
Is remote troubleshooting supported?
With customer consent and secure VPN access, ANJIE’s technical support team may initiate encrypted remote sessions via TeamViewer Embedded for firmware diagnostics and configuration review.