Anyan AYAN-300LB High-Flow 5-Nines PSA Nitrogen Generator

Overview

The Anyan AYAN-300LB is a high-capacity, on-site nitrogen generation system engineered for continuous, reliable production of high-purity nitrogen gas (up to 99.999%) via Pressure Swing Adsorption (PSA) technology. Designed for demanding laboratory, analytical, and industrial applications—including LC-MS, GC carrier gas supply, inert blanketing, and controlled-atmosphere packaging—the unit integrates all essential subsystems into a single skid-mounted platform: an oil-free scroll air compressor, refrigerated air dryer, multi-stage filtration (including a dedicated activated carbon oil scavenger), dual-tower PSA separation module, air receiver tank, nitrogen buffer tank, and real-time monitoring instrumentation. The core separation mechanism relies on the selective adsorption of oxygen, CO₂, moisture, and trace hydrocarbons onto carbon molecular sieve (CMS) beds under elevated pressure, followed by rapid depressurization to regenerate the adsorbent—enabling uninterrupted nitrogen delivery with stable purity, pressure, and flow.

Key Features

• Integrated air compression and purification: Eliminates dependency on external compressed air sources; includes oil-free scroll compressor, refrigerated dryer (−20 °C dew point), and three-stage filtration (particulate, coalescing, and catalytic carbon oil removal) to protect CMS integrity.
• Dual-tower parallel PSA architecture: Ensures continuous nitrogen output with zero interruption during tower regeneration cycles; optimized valve sequencing and pressure equalization minimize energy consumption and extend CMS service life.
• Real-time process monitoring: Built-in electrochemical nitrogen purity analyzer (0–100% O₂ equivalent, resolution 0.001%) and thermal mass flow meter (0–300 L/min, ±1.5% FS accuracy) provide live digital readouts on the front-panel HMI.
• Robust mechanical design: Heavy-duty steel frame with castor wheels and locking brakes enables secure positioning and repositioning in shared lab or pilot-plant environments; vibration-dampened mounting reduces acoustic emission (<65 dB(A) at 1 m).
• Stabilized gas delivery: Air receiver tank buffers compressor pulsation and stabilizes feed pressure to the PSA module; nitrogen buffer tank dampens purity and pressure fluctuations, delivering consistent gas quality required for sensitive instrumentation.
• Customizable purity configuration: Available in four certified purity grades—99.0%, 99.9%, 99.99%, and 99.999%—each validated per ISO 8573-1:2010 Class 2:2:2 (for 99.999% grade) and calibrated against NIST-traceable reference standards.

Sample Compatibility & Compliance

The AYAN-300LB is compatible with all standard laboratory gas interfaces (CGA-580, BS4365, DIN 477), and supports integration with OEM analytical instruments requiring regulated nitrogen supply (e.g., Thermo Fisher, Agilent, Waters). Its internal filtration meets ISO 8573-1 Class 2 for solid particles (≤0.1 µm), Class 2 for water (−40 °C pressure dew point), and Class 1 for oil aerosol (<0.01 mg/m³). All electrical components comply with IEC 61000-6-3 (EMC) and IEC 61000-6-2 (immunity); the control system supports optional audit trail logging aligned with FDA 21 CFR Part 11 requirements when paired with compliant third-party data acquisition software.

Software & Data Management

The embedded microprocessor controller features a 7-inch capacitive touchscreen HMI with multilingual interface (English, German, French, Chinese). It records operational parameters—including inlet pressure, tower differential pressure, purity value, flow rate, runtime hours, and alarm history—for up to 30 days locally. Data export is supported via USB 2.0 (CSV format) or optional RS-485 Modbus RTU protocol for integration into centralized facility monitoring systems (BMS/SCADA). Firmware updates are performed offline via SD card; no cloud connectivity or remote access is implemented by default, ensuring data sovereignty and network isolation per GLP/GMP laboratory policy.

Applications

• Gas chromatography (GC) and GC-MS carrier gas supply, meeting ASTM D6299 and USP <621> specifications for baseline stability and retention time reproducibility.
• LC-MS mobile phase sparging and instrument purge gas, where sub-ppm oxygen and hydrocarbon levels prevent ion source contamination and signal drift.
• Inert atmosphere creation for glove boxes, sample storage cabinets, and reaction vessels in synthetic chemistry and battery R&D labs.
• Blanketing of solvents and reagents in pharmaceutical manufacturing cleanrooms (ISO Class 5–8), supporting ICH Q5C stability protocols.
• Calibration gas blending systems requiring stable, low-moisture nitrogen as diluent or balance gas.

FAQ

What purity grades are available, and how is purity verified?
The AYAN-300LB is factory-configured for one of four purity levels: 99.0%, 99.9%, 99.99%, or 99.999%. Each grade undergoes 72-hour continuous validation using a certified paramagnetic oxygen analyzer traceable to NIST SRM 2628; final certification report includes measured O₂, H₂O, and total hydrocarbon content per ISO 8573-1 Annex B.
Can the unit operate unattended for extended periods?
Yes—designed for 24/7 operation with automatic fault detection, pressure-loss shutdown, and CMS saturation alerts. Scheduled maintenance intervals are defined by runtime hours (e.g., filter replacement every 2000 h, CMS rejuvenation every 20,000 h under nominal load).
Is external cooling water required?
No—the refrigerated air dryer uses closed-loop R134a refrigerant with ambient air condensation; no chilled water connection is needed.
Does the system meet GMP documentation requirements?
The base unit provides IQ/OQ documentation templates and calibration certificates for critical sensors. Full GMP-compliant validation (including PQ and change control) is supported through Anyan’s qualified service engineers upon request.
What is the expected lifetime of the carbon molecular sieve?
Under specified inlet air quality (ISO 8573-1 Class 2:2:2) and proper maintenance, CMS service life exceeds 8 years (≥70,000 operating hours) with <5% performance degradation in nitrogen yield or purity.