Anyan AYAN-AUTOM-12S Automated Water Bath Nitrogen Evaporator

Overview

The Anyan AYAN-AUTOM-12S Automated Water Bath Nitrogen Evaporator is an engineered solution for high-throughput, reproducible solvent removal in analytical laboratories. It operates on the principle of gentle, temperature-controlled nitrogen gas sweeping across sample surfaces immersed in a precisely regulated water bath — a method widely adopted for concentrating volatile organic compounds (VOCs), pesticides, pharmaceutical residues, and environmental analytes prior to GC, HPLC, or LC-MS analysis. Unlike dry-block evaporators, the water bath design ensures uniform thermal distribution and minimizes thermal shock or localized overheating, preserving thermally labile compounds. The system integrates optical endpoint detection, independent channel gas control, and programmable volume termination — enabling unattended operation while maintaining trace-level integrity and compliance with method validation requirements under ISO/IEC 17025 and GLP frameworks.

Key Features

• 12-position parallel processing with independent electromagnetic valve control per channel — eliminating cross-contamination and enabling heterogeneous sample protocols within a single run.
• High-precision optical sensor system calibrated for variable solvent transmittance (including colored or turbid matrices), supporting endpoint detection at near-dry, 0.5 mL, 1 mL, or 2 mL — configurable per vial via touchscreen interface.
• Dual-zone heating architecture with PID-controlled water bath (ambient to 100 °C, ±0.5 °C stability) and pre-heated nitrogen delivery (~45 °C), reducing condensation on needle tips and improving evaporation kinetics without thermal degradation.
• Hydraulic-assisted dual-seal door mechanism combined with an internal recirculating activated carbon exhaust system — ensuring containment of volatile organics and meeting OSHA PEL and laboratory fume hood equivalence standards.
• Auto-refill reservoir with level sensing and overtemperature cutoff; integrated drain and overflow ports compliant with ISO 15190:2020 laboratory safety infrastructure guidelines.
• 7-inch capacitive touchscreen HMI with multi-language support (English, Spanish, German), real-time parameter logging, and 100+ method storage capacity — each with timestamped audit trail exportable via USB.

Sample Compatibility & Compliance

The AYAN-AUTOM-12S accommodates standard 16–20 mm outer diameter test tubes, culture tubes, and volumetric glassware up to 200 mL. Its water bath platform supports round-bottom, conical, and flat-bottom vessels without adapter modification. The system complies with key international standards governing laboratory equipment safety and data integrity: IEC 61010-1 (electrical safety), EN 61326-1 (EMC), and supports FDA 21 CFR Part 11–compliant workflows when paired with validated LIMS integration. All firmware logs include immutable timestamps, user ID tags, and change history — essential for GLP/GMP audits and ISO/IEC 17025 method documentation.

Software & Data Management

No proprietary software installation is required. All configuration, monitoring, and data export are performed directly through the embedded Linux-based HMI. Each run generates a CSV-formatted log file containing start/stop times, temperature profiles, gas pressure traces, endpoint events per channel, and operator ID. Files are saved to internal flash memory (8 GB) and exportable via USB 2.0 port. Optional RS-485 Modbus RTU interface enables integration into centralized lab automation systems (e.g., LabVantage, STARLIMS) for automated job queuing and electronic batch record generation.

Applications

• Environmental testing: EPA Methods 508.1, 525.3, and 8081B for pesticide residue concentration in water, soil, and sediment extracts.
• Clinical toxicology: Preparation of urine and plasma samples for amphetamine, opioid, and benzodiazepine screening via LC-MS/MS.
• Food safety: Multi-residue analysis per EU SANTE/11813/2021 guidelines, including mycotoxin and veterinary drug extraction from milk, honey, and meat homogenates.
• Pharmaceutical QC: Residual solvent removal from API intermediates per ICH Q3C(R8), ensuring compliance with USP <467> and Ph. Eur. 2.4.24.
• Forensic chemistry: Controlled evaporation of seized drug extracts prior to GC-FID confirmation, minimizing loss of low-boiling volatiles (e.g., methanol, acetone).

FAQ

Does the AYAN-AUTOM-12S support remote monitoring or network connectivity?
No built-in Ethernet or Wi-Fi module is included; however, the RS-485 Modbus RTU port allows integration with building management systems or SCADA platforms using standard industrial gateways.
What maintenance is required for long-term optical sensor accuracy?
The optical sensors require no routine calibration; periodic cleaning of the quartz viewport with isopropanol and lint-free wipes every 200 runs is recommended to maintain signal fidelity.
Can the system be validated for GxP environments?
Yes — IQ/OQ documentation templates are provided, and the device meets hardware prerequisites for PQ execution per ASTM E2500-13. Full 21 CFR Part 11 readiness requires external LIMS or ELN integration for electronic signatures and audit trail consolidation.
Is nitrogen purity specification defined for optimal performance?
Instrument performance is validated using ≥99.998% pure nitrogen (Grade 5.0); use of lower-purity gas may accelerate moisture accumulation in pre-heating lines and necessitate more frequent desiccant replacement.
What safety certifications does the unit carry?
CE-marked per Machinery Directive 2006/42/EC and Low Voltage Directive 2014/35/EU; tested to IEC 61010-1:2010 + A1:2019 for laboratory electrical equipment safety.