ANYAN AYAN-DC36S Smart Fully Enclosed Water-Bath Nitrogen Evaporator with 36-Position Sample Capacity

Overview

The ANYAN AYAN-DC36S is a laboratory-grade, fully enclosed nitrogen evaporator engineered for precise, reproducible solvent removal under inert atmosphere. Unlike open-bay or semi-enclosed systems, this instrument employs a sealed water-bath heating architecture combined with preheated nitrogen delivery and independent pneumatic control—designed to minimize analyte loss, prevent cross-contamination, and eliminate ambient volatile emissions. Its core principle relies on controlled convective heat transfer via thermostatically regulated water bath (ambient to 100 °C), while nitrogen gas—pre-warmed to approximately 45 °C—is delivered through individually metered solenoid valves to each of the 36 sample positions. This dual thermal management strategy accelerates evaporation kinetics without inducing thermal degradation or cold condensation at the needle tip—a known source of carryover in conventional nitrogen blow-down systems.

Key Features

• 7-inch high-resolution LCD touchscreen interface with intuitive navigation, supporting multilingual UI configuration (English default) and real-time parameter monitoring.
• 50-segment programmable temperature ramping across five distinct operational modes (e.g., hold, linear ramp, step, profile, and auto-shutdown), enabling method-specific thermal protocols compliant with SOP-driven workflows.
• Fully enclosed chamber with dual-seal door system and integrated recirculating fan—eliminates need for external fume hood connection while maintaining Class II containment integrity per ISO 15190:2020 guidelines for laboratory safety.
• Preheated nitrogen inlet ensures consistent gas temperature (~45 °C) at point-of-delivery; mitigates condensation formation on concentrator needles and reduces risk of sample re-deposition or oxidation.
• Independent electromagnetic flow control per channel (36 channels) guarantees uniform pressure distribution (0–0.8 MPa range) and eliminates inter-channel variability—critical for quantitative recovery in regulated bioanalytical applications.
• Two-side transparent observation windows (front + side) and module-level visibility allow continuous visual monitoring of liquid meniscus without opening the chamber—supporting GLP-compliant process verification.
• Onboard data logging stores up to 10,000 timestamped records including setpoints, actual temperatures, runtime, and alarm events—exportable via USB for audit trail generation.

Sample Compatibility & Compliance

The AYAN-DC36S accommodates standard borosilicate glass test tubes and centrifuge vials with outer diameters ranging from 10 mm to 29 mm. Its modular support platform accepts interchangeable aluminum or stainless-steel blocks, allowing adaptation to common formats including 13 × 100 mm, 16 × 150 mm, and 29 × 150 mm configurations. The system meets mechanical safety requirements outlined in IEC 61010-1:2010 and complies with electromagnetic compatibility standards EN 61326-1:2013. While not certified for IVD or medical device use, its design supports alignment with FDA 21 CFR Part 11 when paired with validated software extensions (available upon request). All wetted components are chemically resistant to common organic solvents (e.g., acetonitrile, methanol, ethyl acetate) and compatible with USP material classification for pharmaceutical residual analysis.

Software & Data Management

The embedded firmware includes non-volatile memory for storing ≥100 user-defined methods and maintains full audit trail functionality—including operator ID tagging (via optional RFID badge integration), parameter change logs, and timestamped start/stop events. Data export is supported via USB 2.0 port in CSV format, facilitating import into LIMS platforms or statistical analysis tools such as JMP or GraphPad Prism. Optional PC-based software (ANYAN ControlSuite v3.2) provides remote monitoring, method synchronization across multiple units, and automated report generation aligned with ISO/IEC 17025 documentation requirements. All electronic records conform to ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available) for regulatory submissions.

Applications

This evaporator is routinely deployed in environmental testing labs for EPA Method 505/525 derivatization workflows, clinical research facilities for LC-MS/MS sample preparation prior to steroid hormone quantification, and food safety laboratories performing pesticide residue analysis per AOAC 2007.01. It is also validated for residual solvent testing in API manufacturing environments under ICH Q3C(R8) guidelines. Typical use cases include concentration of extracts from solid-phase extraction (SPE), QuEChERS, and liquid–liquid extraction (LLE); parallel processing of calibration standards; and high-throughput cleanup of plasma, urine, soil, and water matrices. Its sealed architecture makes it suitable for volatile organic compound (VOC) handling where exposure limits (e.g., OSHA PELs) must be strictly observed.

FAQ

Is the AYAN-DC36S compatible with nitrogen generators?

Yes—the unit accepts inlet pressure between 0.2–0.8 MPa and is compatible with both cylinder-based and membrane-type nitrogen generators meeting ISO 8573-1:2010 Class 2 purity specifications.
Can the water bath be filled with alternatives to deionized water?

Only deionized or distilled water is recommended to prevent mineral scaling and corrosion of the stainless-steel bath chamber. Ethylene glycol–water mixtures are not supported.
Does the system support 21 CFR Part 11 compliance out-of-the-box?

The base firmware supports audit trails and electronic signatures when used with validated third-party LIMS integrations; full Part 11 compliance requires documented IQ/OQ/PQ validation performed by the end user or qualified service provider.
What maintenance intervals are recommended for optimal performance?

Daily visual inspection of seals and tubing; weekly cleaning of bath chamber and viewing windows with acetone-dampened lint-free cloth; quarterly calibration verification of temperature sensor against NIST-traceable reference thermometer.
Is remote firmware update capability available?

Firmware updates are distributed via USB flash drive only—no network connectivity or cloud-based update mechanism is implemented to maintain air-gapped security in regulated environments.