Anyan AYAN-DC48S 48-Position Automated Nitrogen Evaporator with Water Bath Heating

Overview

The Anyan AYAN-DC48S is a laboratory-grade automated nitrogen evaporator engineered for precise, reproducible solvent removal in analytical sample preparation workflows. It operates on the principle of gentle inert-gas displacement—introducing controlled streams of high-purity nitrogen across the surface of heated liquid samples to accelerate solvent evaporation while minimizing thermal degradation and analyte loss. Unlike dry-block systems, this model employs a thermostatically regulated water bath heating system, ensuring superior temperature homogeneity and reduced risk of localized overheating—a critical advantage when processing thermolabile compounds such as pesticides, pharmaceutical actives, or endogenous metabolites. Designed for compliance-critical environments, the AYAN-DC48S supports method traceability through embedded data logging, programmable temperature profiles, and secure operational parameters—all aligned with GLP and ISO/IEC 17025 laboratory management expectations.

Key Features

• 48-position modular sample block accommodating standard 16 mm OD test tubes (customizable bore diameters available upon request)
• 7-inch high-resolution capacitive touchscreen interface with intuitive navigation and real-time status feedback
• 50-segment programmable temperature control enabling complex ramp/soak protocols for optimized analyte recovery
• Independent electromagnetic valve control for each gas channel—ensuring consistent flow distribution and eliminating cross-contamination risks
• Dual-sealed transparent observation doors with internal forced-air recirculation, eliminating volatile leakage without requiring external fume hood integration
• Auto-pressure regulation system maintaining uniform nitrogen delivery across all 48 channels, reducing gas consumption by up to 35% versus manual manifold setups
• Built-in non-volatile memory storing ≥100 user-defined methods with timestamps, temperature logs, and runtime history for audit-ready documentation
• Front and side dual-view transparent windows enabling unobstructed visual monitoring of sample volume reduction and surface agitation

Sample Compatibility & Compliance

The AYAN-DC48S is validated for use with common organic solvents including acetonitrile, methanol, ethyl acetate, hexane, and dichloromethane—provided flash points exceed 100 °C. It is not intended for use with highly flammable solvents (e.g., diethyl ether, petroleum ether) or corrosive reagents (strong acids/bases), which may compromise gasket integrity and sensor longevity. All electrical components conform to IEC 61010-1 safety standards for laboratory equipment. The unit features grounded three-pin power input and internal insulation monitoring to prevent electric shock hazards during water bath operation. While not certified under FDA 21 CFR Part 11, its parameter-locking function, audit trail-capable data storage, and password-protected configuration menus support alignment with GMP/GLP documentation requirements for QC laboratories conducting residue analysis per AOAC, EPA Method 525.3, or ISO 17025-accredited procedures.

Software & Data Management

No proprietary software installation is required—the AYAN-DC48S operates autonomously via its onboard firmware. All method parameters—including setpoint temperature, dwell time, pressure setpoint, and segment sequence—are configured directly on the touchscreen and retained in EEPROM memory after power cycling. Each run generates a timestamped log entry recording actual bath temperature every 10 seconds, total elapsed time, and final shutdown condition. Export functionality is not provided; however, users may manually transcribe critical parameters into LIMS or ELN systems using standardized nomenclature (e.g., “AYAN-DC48S_RunID_20240522_T100_P0.45_t15”). For laboratories implementing digital workflow validation, the device’s deterministic behavior—repeatable thermal response, fixed valve actuation timing, and stable pressure regulation—enables straightforward IQ/OQ protocol development.

Applications

• Pesticide residue analysis in food and agricultural commodities (AOAC 2007.01, EN 15662)
• Environmental monitoring of PAHs, PCBs, and organochlorine compounds in soil/water extracts (EPA 8270, ISO 18856)
• Pharmaceutical impurity profiling and stability-indicating assay sample cleanup (ICH Q2(R2))
• Clinical toxicology specimen preparation prior to GC-MS or LC-MS/MS analysis
• Natural product isolation workflows requiring low-temperature concentration of heat-sensitive terpenoids or glycosides
• Forensic drug screening where quantitative recovery of volatile analytes (e.g., cannabinoids, benzodiazepines) is essential

FAQ

Is the AYAN-DC48S compatible with ISO/IEC 17025 accredited laboratories?
Yes—its stable thermal performance, programmable repeatability, and built-in data logging support method validation and ongoing equipment verification per ISO/IEC 17025 clause 6.4.3.
Can I use glass vials with conical bottoms?
Only if they fit securely within the 16 mm-diameter heated wells; conical-bottom vials must maintain vertical alignment and full contact with the bath medium to ensure uniform heating.
What maintenance intervals are recommended?
Inspect O-rings and valve seals every 6 months; clean water bath chamber weekly with deionized water and mild detergent; calibrate temperature sensor annually using a NIST-traceable reference thermometer.
Does the unit include nitrogen gas supply or regulators?
No—users must provide external Grade 5.0 (99.999%) nitrogen with an inline pressure regulator capable of delivering 0–0.8 MPa at ≤10 L/min total flow.
How is overheating prevented during extended runs?
The system incorporates dual redundant thermal cutoffs: one mechanical bimetal switch at 105 °C and one electronic PID-based overtemperature lockout triggered at 102 °C, both disabling heating until manual reset.