ANYAN AYAN-DC48S Fully Enclosed Water Bath Nitrogen Evaporator

Overview

The ANYAN AYAN-DC48S Fully Enclosed Water Bath Nitrogen Evaporator is an engineered solution for controlled, gentle solvent removal in analytical and environmental laboratories. It operates on the principle of inert gas-assisted evaporation: high-purity nitrogen is delivered through precision-adjustable nozzles positioned above sample tubes immersed in a thermostatically regulated water bath. This dual-control architecture—combining uniform conductive heating (via water medium) with laminar nitrogen flow—enables reproducible concentration of heat-sensitive analytes without thermal degradation or oxidation. Unlike dry-block evaporators, the water bath design ensures exceptional temperature homogeneity across all 48 sample positions (±1 °C), critical for inter-sample comparability in multi-analyte workflows such as pesticide residue screening or pharmaceutical impurity profiling. The fully enclosed chamber with dual-sealed access door minimizes ambient contamination, reduces nitrogen consumption, and contains volatile organic compounds—making it suitable for installation in standard laboratory fume hoods compliant with ANSI/AIHA Z9.5 ventilation standards.

Key Features

• 7-inch capacitive touchscreen interface with intuitive navigation, supporting five preconfigured evaporation modes (e.g., ramp-hold, gradient, constant-flow) and up to 50 programmable temperature/time segments.
• Independent pressure control per gas channel via calibrated needle valves, enabling precise nitrogen flow adjustment from 0 to 330 mL/min with real-time visual feedback on the display.
• Modular, interchangeable sample blocks accommodating tubes from 10 mm to 29 mm outer diameter; height-adjustable nozzle array with lockable vertical positioning for optimal gas impingement without splashing.
• Integrated exhaust fan system with activated carbon filter option (accessory) to capture residual vapors, supporting compliance with OSHA permissible exposure limits (PELs) for solvents such as hexane or ethyl acetate.
• Dual-sealed viewing door with tempered safety glass provides unobstructed process monitoring while maintaining containment integrity—validated per IEC 61010-1 for electrical safety and mechanical enclosure performance.
• Over-temperature cut-off, ground-fault circuit interruption (GFCI), and automatic shut-down upon door opening ensure adherence to GLP-aligned operational safety protocols.

Sample Compatibility & Compliance

The AYAN-DC48S is validated for use with common extraction solvents including acetonitrile, methanol, dichloromethane, and ethyl acetate—but explicitly excludes substances with flash points below 100 °C (e.g., diethyl ether, petroleum ether) or strongly corrosive media (pH 11). Its stainless steel water bath vessel and PTFE-coated internal surfaces resist chemical attack under routine operating conditions. The instrument conforms to ISO/IEC 17025 requirements for equipment qualification in accredited testing laboratories and supports audit-ready documentation when paired with optional electronic logbook software. All electrical components meet CE marking directives (2014/30/EU EMC and 2014/35/EU LVD), and the enclosure design facilitates cleaning validation per FDA Guidance for Industry: Process Validation (2011).

Software & Data Management

While the base unit operates via embedded firmware, optional USB data logging enables timestamped export of temperature setpoints, actual bath temperatures, elapsed time, and gas pressure readings in CSV format. This raw dataset supports retrospective analysis for method transfer documentation and satisfies minimum ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate) required under 21 CFR Part 11 when used with validated third-party LIMS integration. The touchscreen interface retains the last 10 executed methods—including user ID input fields—to support multi-user environments under GxP-regulated quality systems.

Applications

This evaporator is routinely deployed in:

• Pesticide residue analysis (AOAC 2007.01, EN 15662) for fruits, vegetables, and cereals, where matrix complexity demands consistent, low-oxidation concentration prior to GC-MS/MS injection.
• Environmental water testing (EPA Methods 508.1, 8081B) involving trace-level organochlorine extraction from drinking water and wastewater matrices.
• Clinical and forensic toxicology workflows requiring parallel processing of plasma or urine samples prior to LC-MS quantification of benzodiazepines or opioids.
• Pharmaceutical stability studies (ICH Q5C) where residual solvent removal from lyophilized intermediates must avoid polymorphic transformation.
• Food authenticity testing (e.g., melamine detection in dairy products per ISO/TS 22002-1), where nitrogen blanking prevents artifact formation during derivatization steps.

FAQ

Is the AYAN-DC48S suitable for flammable solvents with flash points below 100 °C?

No. Operation with solvents such as diethyl ether, pentane, or carbon disulfide is strictly prohibited due to explosion risk. Only solvents with flash points ≥100 °C are permitted.

Can the water bath be filled with alternatives to deionized water?

Only deionized or distilled water is recommended. Tap water introduces mineral deposits that impair heater efficiency and accelerate corrosion; glycerol/water mixtures are not supported.

What maintenance intervals are required for GLP-compliant operation?

Perform visual inspection of seals and tubing weekly; clean the water bath chamber and nozzles biweekly using 70% isopropanol; verify temperature calibration quarterly using NIST-traceable RTD probes.

Does the unit support remote monitoring via Ethernet or Wi-Fi?

No. The AYAN-DC48S lacks network connectivity. Remote oversight requires external industrial PLC integration or standalone data loggers with analog output modules.

Is validation documentation available for IQ/OQ/PQ protocols?

Yes. Factory-issued DQ/IQ templates and calibration certificates (including as-found/as-left data for temperature and pressure sensors) are provided with each shipment. Custom OQ protocols can be developed jointly with ANYAN’s technical support team.