ANYAN CYZDCQ-6 Automated Liquid-Liquid Extractor with Vertical Oscillation

Overview

The ANYAN CYZDCQ-6 Automated Liquid-Liquid Extractor is an engineered solution for reproducible, operator-safe liquid-phase extraction in regulated laboratory environments. It operates on a closed-loop pneumatic agitation principle: controlled compressed air induces vigorous vertical oscillation between aqueous and organic phases within standardized separatory funnels, promoting interfacial mass transfer through repeated collision and dispersion—without manual shaking or venting. This method eliminates direct human exposure to volatile, toxic, or corrosive solvents (e.g., chloroform, hexane, MTBE), aligning with occupational health standards such as OSHA 29 CFR 1910.1200 and EU CLP Regulation (EC) No 1272/2008. The system supports full automation of the entire extraction workflow—including reagent dosing, phase mixing, gravity-driven settling, aqueous/organic layer separation, waste discharge, and internal cleaning—reducing analyst intervention to loading/unloading only. Its architecture is designed for compliance-ready operation in environmental testing labs (EPA Method 1664, ISO 11348), pharmaceutical QC (USP <1058>, ICH Q2(R2)), and food safety analysis (AOAC 993.14).

Key Features

• 6-position independent processing station with individual parameter control per channel—enabling heterogeneous sample sets in a single run.
• 7-inch industrial-grade color TFT touchscreen with intuitive HMI interface; all parameters (extraction time, cycle count, oscillation intensity, rest interval, wash duration) are programmable with password-protected user profiles.
• Pneumatically driven vertical oscillation mechanism with adjustable pressure regulation (0–6 bar), ensuring consistent energy input across viscosity ranges (1–500 mPa·s).
• High-precision peristaltic metering pumps for automated, gravimetrically verified delivery of both sample and extractant—minimizing volumetric error (<±0.5% RSD at 10 mL).
• Integrated stainless-steel telescopic waste collection tray with built-in vacuum-assisted filtration; dual-stage activated carbon adsorption modules for exhaust gas (VOCs, H₂S, Cl₂) and spent liquid effluent treatment.
• Wide-bore, wide-angle pressurized spray nozzles deliver uniform 360° interior rinsing of separatory funnels (250–2000 mL capacity), validated for >98% residual solvent removal per cycle (per ASTM D7213).
• Six independent pressure-regulated circuits with overload protection (overcurrent, overvoltage, ground-fault interrupt), conforming to IEC 61010-1:2010 safety requirements.
• Modular quick-release clamping system for rapid interchange of funnel holders—compatible with standard ASTM D3412-compliant glass or PTFE-lined separatory funnels.
• Remote monitoring capability via Ethernet/Wi-Fi with optional SMS alert integration (configurable via web-based API); audit trail logging enabled for GLP/GMP environments.

Sample Compatibility & Compliance

The CYZDCQ-6 accommodates routine liquid-liquid extraction protocols for priority pollutants in water, wastewater, soil leachates, and biological matrices. Validated applications include EPA Methods 1664 (n-hexane extractable material), 508.1 (organochlorine pesticides), 525.3 (semivolatile organics), and ISO 11348-3 (toxicity assessment). All fluid-contact surfaces are constructed from chemically inert materials: PTFE valves, borosilicate glass funnels, and EPDM gaskets. The system meets CE marking requirements (2014/30/EU EMC Directive, 2014/35/EU LVD), and its data integrity architecture supports FDA 21 CFR Part 11 compliance when paired with validated third-party LIMS software.

Software & Data Management

Embedded firmware provides real-time process visualization, event-triggered logging (start/stop, fault, alarm), and exportable CSV reports containing timestamped parameter sets, cycle counts, and error codes. Audit trail functionality records user ID, action type, and modification time for every configuration change. Optional PC-based AnyanControl™ Suite enables method library management, remote scheduling, and trend analysis of extraction efficiency metrics across batches. Data encryption (AES-256) and role-based access control ensure alignment with ISO/IEC 27001 information security frameworks.

Applications

• Environmental monitoring: oil & grease (TPH), phenols, PAHs, PCBs, and anionic surfactants in surface water and groundwater.
• Pharmaceutical impurity profiling: isolation of genotoxic nitrosamines from drug substance intermediates.
• Food safety: determination of pesticide residues (organophosphates, carbamates) in fruit/vegetable extracts.
• Metallurgical process control: selective recovery of cobalt/nickel from hydrometallurgical leach solutions.
• Academic research: kinetic studies of partition coefficients (log P) under controlled agitation intensity and contact time.

FAQ

What types of separatory funnels are compatible with the CYZDCQ-6?
Standard tapered-glass funnels (250 mL, 500 mL, 1000 mL, and 2000 mL) with PTFE stopcocks and matching clamp adapters are supported. Custom PTFE-lined funnels may be used upon validation.
Does the system support unattended overnight operation?
Yes—equipped with thermal cutoff, pressure relief valves, and auto-shutdown on fault detection, it is certified for continuous 24-hour operation in Class II laboratory environments.
How is extraction efficiency quantified and verified?
Efficiency is calculated from recovery rates of certified reference materials (e.g., NIST SRM 1643e) spiked into matrix blanks; the instrument’s programmable “efficiency index” (0–999) correlates with % recovery normalized to theoretical yield.
Can the system integrate with existing LIMS or ELN platforms?
Via RESTful API or OPC UA protocol; pre-built connectors available for Thermo Fisher SampleManager, LabVantage, and Benchling.
Is validation documentation provided for IQ/OQ/PQ protocols?
Yes—factory-issued Installation Qualification (IQ) and Operational Qualification (OQ) templates are included; Performance Qualification (PQ) support is available through Anyan’s Application Support Team.