Aseeker-600 Accelerated Solvent Extractor
| Brand | KEZHE SHANGHAI |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Direct Manufacturer |
| Regional Classification | Domestic (China) |
| Model | Aseeker-600 |
| Instrument Category | Solid-Liquid Extraction |
| Temperature Range | Ambient to 200 °C (±0.5 °C) |
| Pressure Range | 0–20 MPa (±0.3 MPa) |
| Extraction Cell Volumes | 10 mL / 20 mL / 40 mL |
| Throughput | 6 samples in 20 min |
| Dimensions (W×D×H) | 770 mm × 608 mm × 755 mm |
| Weight | 95 kg |
| Solvent Consumption per Sample | 5–200 mL |
| Pump Flow Rate | 0.1–50 mL/min |
| Power Requirement | 100–240 VAC ±10 %, 50–60 Hz |
| Max Power Consumption | 1.7 kW |
| Gas Supply | Lab-grade nitrogen, 0.4–1 MPa |
| Solvent Mixing Capability | Up to 4 solvents |
| Collection Vial Capacity | 250 mL |
| Cleaning Stations | 6 |
| Sample Contact Materials | PEEK, PTFE, 316L stainless steel, ceramic |
Overview
The Aseeker-600 Accelerated Solvent Extractor is a high-throughput, fully automated solid-liquid extraction system engineered for precision, reproducibility, and regulatory compliance in analytical laboratories. It operates on the principle of accelerated solvent extraction (ASE®), applying elevated temperature and pressure to enhance solubility and mass transfer kinetics—enabling rapid, efficient recovery of analytes from solid or semi-solid matrices without thermal degradation. By maintaining solvent above its boiling point while remaining in the liquid phase (via pressurization), the Aseeker-600 achieves extraction efficiencies comparable to Soxhlet but in <5% of the time. Designed for routine use in environmental monitoring, food safety testing, pharmaceutical quality control, and agricultural residue analysis, it supports standardized workflows aligned with U.S. EPA Method 3545A, Chinese National Standard GB 23200.9–2016, and HJ 834–2017 for semi-volatile organic compounds (SVOCs) in soil and sediment.
Key Features
- Six independent extraction channels with individual inlet/outlet valves and pressure transducers—ensuring zero cross-contamination and uninterrupted operation if one channel requires maintenance;
- Integrated real-time nitrogen supply monitoring; automatic alerting and process suspension upon detected pressure drop below threshold;
- Dual-layer safety architecture: mechanical overpressure relief (20 MPa rated) and electronic overtemperature cutoff (200 °C max, ±0.5 °C stability);
- On-board post-extraction filtration: extract solution is automatically filtered through inert frits into collection vials prior to transfer;
- Modular solvent management system with four-channel gradient mixing, programmable rinse cycles, and dedicated waste routing to separate solvent recovery or disposal containers;
- PEEK, PTFE, 316L stainless steel, and ceramic wetted-path components—chemically resistant across acidic, basic, and halogenated solvent systems (e.g., acetone, dichloromethane, ethyl acetate, hexane);
- Intuitive 10.1-inch capacitive touchscreen interface with preloaded method templates, audit-trail-enabled user authentication, and configurable run logs;
- Low solvent consumption profile (5–200 mL per sample) reduces operational cost and hazardous waste generation;
- Compact footprint (770 mm × 608 mm × 755 mm) optimized for standard laboratory benchtop integration without external chillers or exhaust hoods.
Sample Compatibility & Compliance
The Aseeker-600 accommodates heterogeneous solid and semi-solid samples—including soils, sediments, sludges, plant tissues, animal feed, powdered pharmaceuticals, and composite food matrices—within standardized extraction cells (10 mL, 20 mL, 40 mL). Its temperature and pressure control fidelity (±0.5 °C, ±0.3 MPa) meets the instrumental performance criteria specified in ISO 13877, ASTM D7689, and USP <2021> for extraction validation. The system supports GLP- and GMP-aligned data integrity requirements through timestamped method execution logs, operator ID tracking, and non-modifiable raw data export (CSV, PDF). When configured with optional network connectivity, it complies with FDA 21 CFR Part 11 for electronic records and signatures, including role-based access control and full audit trail retention.
Software & Data Management
Control and monitoring are executed via KEZHE’s proprietary ASE-Link™ software, compatible with Windows 10/11 and deployable on local workstations or centralized lab servers. The software provides method development wizards for solvent selection, temperature ramping, static/dynamic cycle definition, flush volume optimization, and purge duration calibration. All extraction parameters—including real-time pressure curves, temperature profiles, and pump flow traces—are logged at 1 Hz resolution and stored with SHA-256 hash verification. Data exports support LIMS integration via ASTM E1384-compliant XML schemas and include metadata fields for sample ID, analyst, instrument serial number, calibration status, and environmental ambient conditions. Remote diagnostics and firmware updates are supported over secure HTTPS with TLS 1.2 encryption.
Applications
- Environmental analysis: pesticide residues (organochlorines, organophosphates), PAHs, PCBs, dioxins, and phthalates in soil, sediment, and biosolids per EPA 3545A and HJ 834–2017;
- Food safety testing: fat/oil extraction for AOAC 996.06 compliance; mycotoxin recovery from cereals and nuts; veterinary drug residues in meat and dairy products;
- Pharmaceutical R&D: active pharmaceutical ingredient (API) recovery from excipient blends, residual solvent quantification in solid dosage forms;
- Agricultural research: nutrient leaching studies, herbicide dissipation kinetics in field-collected rhizosphere samples;
- Industrial QC: polymer additive extraction (antioxidants, plasticizers) from thermoplastics and elastomers prior to GC-MS or HPLC analysis.
FAQ
What extraction methods does the Aseeker-600 support?
It supports static, dynamic, and multiple-cycle ASE protocols—including pre-rinse, static hold, flush, and purge phases—with customizable timing, temperature, pressure, and solvent composition.
Is method validation documentation available?
Yes—KEZHE provides IQ/OQ documentation packages, system suitability test (SST) procedures, and traceable calibration certificates for temperature, pressure, and flow sensors.
Can the system be integrated into an automated sample preparation line?
The Aseeker-600 features RS-232, Ethernet, and optional PLC-compatible dry-contact I/O for synchronization with robotic autosamplers or fraction collectors.
What maintenance intervals are recommended?
Valve actuation cycles and pressure sensor calibration are tracked in-system; preventive maintenance is scheduled every 500 runs or 12 months, whichever occurs first.
Does it comply with green chemistry principles?
Yes—the reduced solvent volume (vs. Soxhlet or ultrasonic extraction), energy-efficient heating design, and closed-loop solvent handling minimize environmental impact and align with ACS Green Chemistry Principles #2 and #9.
